Histology: tattoo, amalgam  - tattoo
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Image Name: amalgam_tattoo_1_090401   File Type: jpg
Diagnosis: TATTOO, AMALGAM / TATTOO   Category: deposition disorders /
dental/oral disorder /
hyperpigmentation
Morphology: macular / flat (macule / patch)   Organization: discrete
Pattern: solitary   Color: black
Body Site: mouth, floor of   Age: 59 years
Gender: female   Image Year: 2009
Magnification:40x   Stain: hematoxylin and eosin
Contributor: Greg Hosler, MD, PhD   First  Published: May 06, 2009
Description:The mucosa appears normal. In the submucosa, there is an ill-defined hyperpigmented area.
Comments:This 59 year old woman had a pigmented lesion biopsied from the floor of her mouth to rule out melanoma. This is a common scenario for amalgam tattoos. These lesions develop when metals from dental work leach into the soft tissues. Common metals implicated are silver, mercury, aluminum, etc. On histology, the pigment may be black, brown, or golden. The main differential diagnosis is a melanocytic lesion, like a blue nevus, but the tattoo pigment is acellular and often accentuated on elastic fibers.
Related Links:
Related Images: amalgam_tattoo_2_090401 
Other Resources: PubMed: tattoo, amalgam OMIM: tattoo, amalgam
MedlinePlus: tattoo, amalgam Archives of Dermatology: tattoo, amalgam
eMedicine: tattoo, amalgam Dermatology Online: tattoo, amalgam
PubMed: tattoo OMIM: tattoo
MedlinePlus: tattoo Archives of Dermatology: tattoo
eMedicine: tattoo Dermatology Online: tattoo
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