© 2001-05, DermAtlas | Image Name: | neurofibromatosis_1_041012 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMA, PLEXIFORM / NEUROFIBROMATOSIS / NEUROFIBROMA | Category: | genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | hand / finger | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | large spongy subcutaneous tumor of the palm and the proximal fourth finger | ||||
| Comments: | This 62-year-old man, who had multiple café au lait macules at brith, began to develop small cutaneous neurofibromas shortly before puberty. The plexiform neurofibroma on hisleft hand had been present since birth and recurred after 2 surgical excisions. He also had Lisch nodules and orthopedic complications of neurofibromatosis type 1. | ||||
| Related Images: | All related Images neurofibromatosis_4_041012 neurofibromatosis_3_041012 neurofibromatosis_2_041012 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_2_041012 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMA, PLEXIFORM / NEUROFIBROMATOSIS / NEUROFIBROMA | Category: | genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | hand / finger | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | large spongy subcutaneous tumor of the palm and the proximal fourth finger; 3-6 mm spongy pink nodules | ||||
| Comments: | This 62-year-old man, who had multiple café au lait macules at brith, began to develop small cutaneous neurofibromas shortly before puberty. The plexiform neurofibroma on hisleft hand had been present since birth and recurred after 2 surgical excisions. He also had Lisch nodules and orthopedic complications of neurofibromatosis type 1. | ||||
| Related Images: | All related Images neurofibromatosis_4_041012 neurofibromatosis_3_041012 neurofibromatosis_1_041012 | ||||
© 2001-05, DermAtlas | Image Name: | Neurofibroma_Plexiform_1_030516 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMA, PLEXIFORM / NEUROFIBROMATOSIS | Category: | genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | leg / leg | Age: | 40 years | ||
| Contributor: | Jayalath Thilak, MD | ||||
| Description: | 40 year old female patient presented with swelling of left leg .On examination she was found to have few neurofibroma nodules with plexiform neurofibroma of left leg. | ||||
| Comments: | This 40-year-old woman complained of swelling of her left leg. Examination revealed multiple nodules within a large plexiform neurofibroma. She also had multiple café au lait macules and smaller 0.5-2.0 cm cutaneous neufibromas scattered over the body. | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_2_030430 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / CAFé AU LAIT SPOT / NEUROFIBROMA, PLEXIFORM | Category: | genodermatosis/genetic disorder / hyperpigmentation / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | abdomen / chest axilla (armpit) | Age: | 5 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | soft spongy mass with overlying confluent light brown patches | ||||
| Comments: | This 5-year-old boy had increasing numnbers of café au macules and superfician cutaneous neurofibromas. He also had a solitary plexiform neurofibroma on the right side of the abdomen with a large overlying café au lait spot and loose skin. He was being treated for esotropia. There was no family history of neurofibromatosis. | ||||
| Related Images: | neurofibromatosis_1_030430 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_6_030123 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / NEUROFIBROMA, PLEXIFORM | Category: | genodermatosis/genetic disorder / neonatal dermatology / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | back / trunk arm | Age: | 48 years | ||
| Contributor: | Debabrata Bandyopadhyay, MD | ||||
| Description: | soft comrressible 5 mm to 2 cm skin colored and brown papules and nodules | ||||
| Comments: | This 48-year-old woman presented with multiple disseminated, 2 mm to 5 cm, soft, sessile, asymptomatic, skin-colored and brown papules and nodules. The lesions began to develop at puberty and gradually increased in number and size. A large lesion on her right ear obliterated the ear canal causing hearing impairment. She also had multiple café-au-lait macules and axillary and inguinal freckles that were present since early childhood. Lisch nodules were noted on her irides on ophthalmologic consultation. She was otherwise healthy. Seven family members in three generations had similar skin lesions.. | ||||
| Related Images: | All related Images neurofibromatosis_1_030123 neurofibromatosis_2_030123 neurofibromatosis_3_030123 neurofibromatosis_4_030123 neurofibromatosis_5_030123 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_5_030123 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / NEUROFIBROMA, PLEXIFORM | Category: | genodermatosis/genetic disorder / neoplasm, benign / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | chest / trunk neck | Age: | 48 years | ||
| Contributor: | Debabrata Bandyopadhyay, MD | ||||
| Description: | soft comrressible 5 mm to 2 cm skin colored and brown papules and nodules | ||||
| Comments: | This 48-year-old woman presented with multiple disseminated, 2 mm to 5 cm, soft, sessile, asymptomatic, skin-colored and brown papules and nodules. The lesions began to develop at puberty and gradually increased in number and size. A large lesion on her right ear obliterated the ear canal causing hearing impairment. She also had multiple café-au-lait macules and axillary and inguinal freckles that were present since early childhood. Lisch nodules were noted on her irides on ophthalmologic consultation. She was otherwise healthy. Seven family members in three generations had similar skin lesions.. | ||||
| Related Images: | All related Images neurofibromatosis_1_030123 neurofibromatosis_2_030123 neurofibromatosis_3_030123 neurofibromatosis_4_030123 neurofibromatosis_6_030123 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_4_030123 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / NEUROFIBROMA, PLEXIFORM / NEUROFIBROMA | Category: | genodermatosis/genetic disorder / neoplasm, benign / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | chest / face trunk | Age: | 48 years | ||
| Contributor: | Debabrata Bandyopadhyay, MD | ||||
| Description: | soft comrressible 5 mm to 2 cm skin colored and brown papules and nodules | ||||
| Comments: | This 48-year-old woman presented with multiple disseminated, 2 mm to 5 cm, soft, sessile, asymptomatic, skin-colored and brown papules and nodules. The lesions began to develop at puberty and gradually increased in number and size. A large lesion on her right ear obliterated the ear canal causing hearing impairment. She also had multiple café-au-lait macules and axillary and inguinal freckles that were present since early childhood. Lisch nodules were noted on her irides on ophthalmologic consultation. She was otherwise healthy. Seven family members in three generations had similar skin lesions.. | ||||
| Related Images: | All related Images neurofibromatosis_1_030123 neurofibromatosis_2_030123 neurofibromatosis_3_030123 neurofibromatosis_5_030123 neurofibromatosis_6_030123 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibromatosis_3_030123 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / NEUROFIBROMA, PLEXIFORM | Category: | genodermatosis/genetic disorder / neoplasm, benign / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | ear / face | Age: | 48 years | ||
| Contributor: | Debabrata Bandyopadhyay, MD | ||||
| Description: | soft comrressible 5 mm to 2 cm skin colored and brown papules and nodules | ||||
| Comments: | This 48-year-old woman presented with multiple disseminated, 2 mm to 5 cm, soft, sessile, asymptomatic, skin-colored and brown papules and nodules. The lesions began to develop at puberty and gradually increased in number and size. A large lesion on her right ear obliterated the ear canal causing hearing impairment. She also had multiple café-au-lait macules and axillary and inguinal freckles that were present since early childhood. Lisch nodules were noted on her irides on ophthalmologic consultation. She was otherwise healthy. Seven family members in three generations had similar skin lesions.. | ||||
| Related Images: | All related Images neurofibromatosis_1_030123 neurofibromatosis_2_030123 neurofibromatosis_4_030123 neurofibromatosis_5_030123 neurofibromatosis_6_030123 | ||||
© 2001-05, DermAtlas | Image Name: | neurofibroma_1_010412 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMA, PLEXIFORM / NEUROFIBROMA / NEUROFIBROMATOSIS | Category: | lumps & bumps (plaques, nodules, tumors) / genodermatosis/genetic disorder / hyperpigmentation | ||
| Body Site: | shoulder | Age: | 13 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | fleshy hyperpigmented tumor | ||||
| Comments: | A congenital plexiform neurofibroma slowly increased in size on the shoulder of this 13 year old girl whose sister and mother have neurofibromatosis. | ||||
| Related Images: | neurofibroma_2_010412 | ||||
© DermAtlas, Johns Hopkins University; 2000-2005
Bernard A. Cohen, MD, Christoph U. Lehmann, MD
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