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 © 2001-2009, DermAtlas | Image Name: | pustular_psoriasis_2_090518 | File Type: | jpg | |
| Diagnosis: | PSORIASIS, PUSTULAR / PSORIASIS | Category: | papulosquamous eruptions / vesiculobullous eruptions | ||
| Body Site: | arm | Age: | 14 years | ||
| Contributor: | Shokri Khazal | ||||
| Description: | generalized red papules and plaques with surrounding pustules | ||||
| Comments: | This 14-year-old girl developed progressive generalized red scaly plaques with pustules around the periphery 2 weeks ago associated with fever, high white blood cell count, and general malaise. | ||||
| Related Images: | pustular_psoriasis_4_090518 | ||||
 © 2001-2009, DermAtlas | Image Name: | Neurofibromatosis_1_090518 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / CAFé AU LAIT SPOT / NEUROFIBROMA | Category: | neoplasm, benign / genodermatosis/genetic disorder / hyperpigmentation | ||
| Body Site: | chest / abdomen arm | Age: | 27 years | ||
| Contributor: | Ravi Singh | ||||
| Description: | generalized soft compressible skin colored to light brownish-purple papules and nodules | ||||
| Comments: | This 27-year-old man had an increasing number of soft tissue tumors over much of the skin surface. He had a history of hydrocephalus which was persistent despite treatment with folk remedies. | ||||
 © 2001-2009, DermAtlas | Image Name: | shagreen_patch_with_ash_leaf_macule_1_090518 | File Type: | jpg | |
| Diagnosis: | TUBEROUS SCLEROSIS / SHAGREEN PATCH / COLLAGENOMA / ASH LEAF MACULE | Category: | genodermatosis/genetic disorder | ||
| Body Site: | trunk / back | Age: | 16 years | ||
| Contributor: | Yashpal Manchanda, MD | ||||
| Description: | large soft to firm asymptomatic skin colored plaque and 1.5 X 0.5 cm hypopignmented macule | ||||
| Comments: | This mentally retarded adolescent girl with tuberous sclerosis was noted to have a shagreen patch and hypopigmented macule on her lower back at birth. She also had multiple angiofibromas on her face. | ||||
 © 2001-2009, DermAtlas | Image Name: | Pityriais_rosea_1_090518 | File Type: | jpg | |
| Diagnosis: | PITYRIASIS ROSEA | Category: | papulosquamous eruptions | ||
| Body Site: | trunk / abdomen | Age: | 28 years | ||
| Contributor: | Philip Reid | ||||
| Description: | typical fir tree pattern rash on trunk | ||||
| Comments: | This healthy young adult developed a diffuse truncal eruption comprised of round to oval annular red papules many with trailing central scale. | ||||
 © 2001-2009, DermAtlas | Image Name: | pustular_psoriasis_4_090518 | File Type: | jpg | |
| Diagnosis: | PSORIASIS, PUSTULAR / PSORIASIS | Category: | papulosquamous eruptions / vesiculobullous eruptions | ||
| Body Site: | back | Age: | 14 years | ||
| Contributor: | Shokri Khazal | ||||
| Description: | generalized red papules and plaques with surrounding pustules | ||||
| Comments: | This 14-year-old girl developed progressive generalized red scaly plaques with pustules around the periphery 2 weeks ago associated with fever, high white blood cell count, and general malaise. | ||||
| Related Images: | pustular_psoriasis_2_090518 | ||||
 © 2001-2009, DermAtlas | Image Name: | Seborrhoic_Dermatitis_Scalp_1_090518 | File Type: | jpg | |
| Diagnosis: | DERMATITIS, SEBORRHEIC | Category: | papulosquamous eruptions | ||
| Body Site: | head / scalp | Age: | 12 years | ||
| Contributor: | Ravi Singh | ||||
| Description: | scaly patches with crusts and hair loss | ||||
| Comments: | This 12-year-old boy was evaluated for crusted plaques on the sscalp associated with hair loss. The eruption cleared with homeopathic medication. | ||||
 © 2001-2009, DermAtlas | Image Name: | vulva_nevus_2_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, GENITAL / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | vulva (labia) | Age: | 10 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | The melanocytic nests are large and expansile. They are located at all positions along the retia. There is the appearance of loss of cellular cohesion within the nests. Individual melanocytes are enlarged. Mitotic activity is not appreciated. | ||||
| Comments: | This 10 year old female presented with a pigmented papule on her vulva. A subset of genital nevi look unremarkable clinically but have atypical histologic features. This is well-described in the literature. Genital nevi include those on the labia, mons, perineum, penis and scrotum. The histologic features may mimic nodular melanoma. Often times, these nevi have large expansile nests, located at all positions along the retia. There is typically loss of cellular cohesion. There may be cytologic atypia, both epidermally and dermally. Rare mitoses may even be observed. Because it is rare for premenapausal women to develop vulvar melanoma, these features should be heavily scrutinized and the lesion excised if in doubt [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | vulva_nevus_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | vulva_nevus_1_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, GENITAL / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | vulva (labia) | Age: | 10 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | At low power, the epidermis is acanthotic and papillomatous. Thre is a cellular nevomelanocytic lesion, involving the epidermis and dermis. There is overall symmetry. | ||||
| Comments: | This 10 year old female presented with a pigmented papule on her vulva. A subset of genital nevi look unremarkable clinically but have atypical histologic features. This is well-described in the literature. Genital nevi include those on the labia, mons, perineum, penis and scrotum. The histologic features may mimic nodular melanoma. Often times, these nevi have large expansile nests, located at all positions along the retia. There is typically loss of cellular cohesion. There may be cytologic atypia, both epidermally and dermally. Rare mitoses may even be observed. Because it is rare for premenapausal women to develop vulvar melanoma, these features should be heavily scrutinized and the lesion excised if in doubt [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | vulva_nevus_2_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | trichoblastoma_2_090401 | File Type: | jpg | |
| Diagnosis: | TRICHOBLASTOMA / NEVUS SEBACEUS | Category: | neoplasm, adnexal, follicular / neoplasm, benign | ||
| Body Site: | scalp | Age: | 54 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | At higher power, these basaloid collections form primitive structures, with finger- or floret-like projections into the hypercellular stroma. There are scattered suggestions of papillary mesenchymal bodies, where the stroma sweeps into the basaoild structures. There is no signficant peritumoral clefting, atypia or mitotic activity. The cells are monomorphous and bland. | ||||
| Comments: | This 54 year old woman presented with a solitary plaque on her scalp. Clinically, there was a nevus sebaceus (not seen on the biopsy) with a prominent papule, which was biopsied. Trichoblastomas and other basaloid proliferations are commonly observed in association with nevus sebaceus. Some authors consider trichoblastomas to have low-grade malignant potential like a basal cell carcinoma, but the majority, if not all, are benign with a more hamartomatous quality. This is a typical example of a trichoblastoma, mimicking a BCC at low power. Trichoblastomas tend to have organoid or primitive follicular differentiation with a hypercellular and condensed stroma, and lack of peritumor clefting or significant atypia. Pigmentation is common, as in this case. | ||||
| Related Images: | trichoblastoma_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | cyclosporine_induced_gingival_enlargment_1_090518 | File Type: | jpg | |
| Diagnosis: | CYCLOSPORINE INDUCED GINGIVAL HYPERPLASIA / GINGIVAL HYPERPLASIA / DRUG REACTION / GINGIVAL HYPERPLASIA, CYCLOSPORINE INDUCED | Category: | dental/oral disorder / drug reaction / treatment complication | ||
| Body Site: | gingiva | Age: | 33 years | ||
| Contributor: | Roshna Thattankandy, MD | ||||
| Description: | thickening of the gingiva with some crusting and hemorrhage | ||||
| Comments: | This 33-year-old man complained of progressive thickening of his gums associated with bleeding and difficulty chewing food for 6 months. Two years earlier he was diagnosed with aplastic anemia and started on cyclosporine which has been associated with gingival hyperplasia. | ||||
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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD
This page was last updated: Jun-04-2009
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