 | Your DermAtlas query returned 2 ImagesClick on the IMAGE to see an enlargement. |
 © 2001-2009, DermAtlas | Image Name: | vasculitis_2_021113 | File Type: | jpg | |
| Diagnosis: | VASCULITIS / VASCULITIS, LEUKOCYTOCLASTIC / CRYOGLOBULINEMIA | Category: | purpura / collagen vascular disease | ||
| Body Site: | leg / shin | Age: | 43 years | ||
| Contributor: | Raquel Charles | ||||
| Description: | multiple symmetric 2-3 mm purpuric papules | ||||
| Comments: | This 43 year old woman was admitted to the hospital for evaluation of acute worsening of leg pain and weakness that started 10 months earlier. During her hospitalization she developed purpuric papules on her lower legs. A skin biopsy showed a leukocytoclastic vasculitis and direct immunofluorescence demonstrated IgG, M and C3 in dermal blood vessels consistent with polyarteritis nodosa. Laboratory studies revealed cryoglobulinemia with a monoclonal IgM kappa and polyclonal IgG, A, and M. These findings were most consistent with mixed cryoglobulinemia that is often associated with collagen vascular disease. For more details see the cme discussion. | ||||
| Related Images: | All related Images vasculitis_1_021113 vasculitis_4_021113 vasculitis_3_021113 | ||||
 © 2001-2009, DermAtlas | Image Name: | vasculitis_1_021113 | File Type: | jpg | |
| Diagnosis: | VASCULITIS / VASCULITIS, LEUKOCYTOCLASTIC / CRYOGLOBULINEMIA | Category: | purpura / collagen vascular disease | ||
| Body Site: | leg / shin | Age: | 43 years | ||
| Contributor: | Raquel Charles | ||||
| Description: | multiple symmetric 2-3 mm purpuric papules | ||||
| Comments: | This 43 year old woman was admitted to the hospital for evaluation of acute worsening of leg pain and weakness that started 10 months earlier. During her hospitalization she developed purpuric papules on her lower legs. A skin biopsy showed a leukocytoclastic vasculitis and direct immunofluorescence demonstrated IgG, M and C3 in dermal blood vessels consistent with polyarteritis nodosa. Laboratory studies revealed cryoglobulinemia with a monoclonal IgM kappa and polyclonal IgG, A, and M. These findings were most consistent with mixed cryoglobulinemia that is often associated with collagen vascular disease. For more details see the cme discussion. | ||||
| Related Images: | All related Images vasculitis_2_021113 vasculitis_4_021113 vasculitis_3_021113 | ||||
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