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| © 2001-2009, DermAtlas | Image Name: | dyschromatosisuniversalis_1_011107 | File Type: | jpg | |
| Diagnosis: | HYPERPIGMENTATION, CONGENITAL / UNIVERSAL DYSCHROMATOSIS / DYSCHROMATOSIS UNIVERSALIS | Category: | hyperpigmentation / hypopigmentation, depigmentation / genodermatosis/genetic disorder | ||
| Body Site: | trunk | Age: | 9 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | mottled confluent hyper and hypopigmented macules | ||||
| Comments: | Universal dyschromatosis (UD) is a generalized leucomelanodermia described in Japan in 1933. Transmission is dominant with variable expression. UD is characterized by alternating hypo and hyperpigmented macules of varying size. The face and the extremities are spared. The dyspigmentation resembles the pigmentary changes of xeroderma pigmentosum, but patients with UD do not demonstrate photosensitivity, defects in DNA repair or an increased risk of skin cancer. The incidence of DU is highest in the French Carribbean islands. | ||||
| Related Images: | dyschromatosisuniversalis_2_011107 | ||||
| © 2001-2009, DermAtlas | Image Name: | dyschromatosisuniversalis_2_011107 | File Type: | jpg | |
| Diagnosis: | HYPERPIGMENTATION, CONGENITAL / UNIVERSAL DYSCHROMATOSIS / DYSCHROMATOSIS UNIVERSALIS | Category: | hyperpigmentation / hypopigmentation, depigmentation / genodermatosis/genetic disorder | ||
| Body Site: | abdomen | Age: | 9 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | mottled confluent hyper and hypopigmented macules | ||||
| Comments: | Universal dyschromatosis (UD) is a generalized leucomelanodermia described in Japan in 1933. Transmission is dominant with variable expression. UD is characterized by alternating hypo and hyperpigmented macules of varying size. The face and the extremities are spared. The dyspigmentation resembles the pigmentary changes of xeroderma pigmentosum, but patients with UD do not demonstrate photosensitivity, defects in DNA repair or an increased risk of skin cancer. The incidence of DU is highest in the French Carribbean islands. | ||||
| Related Images: | dyschromatosisuniversalis_1_011107 | ||||
| © 2001-2009, DermAtlas | Image Name: | erythematoxicum_1_011107 | File Type: | jpg | |
| Diagnosis: | ERYTHEMA TOXICUM NEONATORUM | Category: | neonatal dermatology / vesiculobullous eruptions | ||
| Body Site: | cheek / face | Age: | 2 days | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | Erythema toxicum neonatorum is a benign self limited eruption that may be present at birth, more typically it occurs 24 to 48 hours after birth. 30 to 70% of newborn are affected. Lesions are firm, yellow or white pustules on a red and swollen base. Lesions may be found in face, trunk and limbs. Palms and soles are not involved. Erythema toxicum lasts about five to seven days as crops. Blood eosinophilia is seen in 20% of cases. Erythema toxicum does not usually recur. The etiology of erythema toxicum remains mysterious. | ||||
| Comments: | Erythema toxicum neonatorum is a benign self limted eruption that may be present at birth, but usually occurs 24 to 48 hours after birth. 30 to 70 percent of newborn are affected. Lesions are firm, yellow or white papules and pustules on a red urticarial edematous base. Lesions may be found on the face, trunk and limbs. Palms and soles are not usually involved. Lesions, which rapidly change from hour to hour, recur in crops for 2 to 7 days. Infants appear well without symptoms. Blood eosinophilia is seen in 20 percent of cases, and the cause is unknown. Erythema toxicum must be distinguished from more serious vesiculopustular eruptions of the newborn including staphylococcal pustulosis, herpes simplex, varicella, candidiasis, and listeriosis. | ||||
| © 2001-2009, DermAtlas | Image Name: | parvo_2_011106 | File Type: | jpg | |
| Diagnosis: | PARVOVIRUS GLOVES AND SOCKS SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | purpura / infections and infestations / reactive erythema | ||
| Body Site: | foot | Age: | 40 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | purpuric papules with confluence in some areas | ||||
| Comments: | This acute acral dermatosis was first described in 1990 occuring predominantly in adults. The hands, feets and perineum are affected by purpuric papules that may become confluent. Oral and genital ulcerations are frequently observed. Fever can follow a few days after the onset of the exanthem. This eruption was described during first infection by Parvovirus B 19, measles, Epstein-Bar virus and Cytomegalovirus infection. The eruption usually clears within 2 weeks. | ||||
| Related Images: | All related Images parvo_1_011106 Parvo_3_011106 | ||||
| © 2001-2009, DermAtlas | Image Name: | Parvo_3_011106 | File Type: | jpg | |
| Diagnosis: | PARVOVIRUS GLOVES AND SOCKS SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | purpura / infections and infestations / reactive erythema | ||
| Body Site: | foot / foot | Age: | 40 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | purpuric papules with confluence in some areas | ||||
| Comments: | This acute acral dermatosis was first described in 1990 occuring predominantly in adults. The hands, feets and perineum are affected by purpuric papules that may become confluent. Oral and genital ulcerations are frequently observed. Fever can follow a few days after the onset of the exanthem. This eruption was described during first infection by Parvovirus B 19, measles, Epstein-Bar virus and Cytomegalovirus infection. The eruption usually clears within 2 weeks. | ||||
| Related Images: | All related Images parvo_1_011106 parvo_2_011106 | ||||
| © 2001-2009, DermAtlas | Image Name: | parvo_1_011106 | File Type: | jpg | |
| Diagnosis: | PARVOVIRUS GLOVES AND SOCKS SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | purpura / infections and infestations / reactive erythema | ||
| Body Site: | vulva (labia) / buttock perineum / genital | Age: | 40 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | purpuric papules with confluence in some areas | ||||
| Comments: | This acute acral dermatosis was first described in 1990 occuring predominantly in adults. The hands, feets and perineum are affected by purpuric papules that may become confluent. Oral and genital ulcerations are frequently observed. Fever can follow a few days after the onset of the exanthem. This eruption was described during first infection by Parvovirus B 19, measles, Epstein-Bar virus and Cytomegalovirus infection. The eruption usually clears within 2 weeks. | ||||
| Related Images: | All related Images Parvo_3_011106 parvo_2_011106 | ||||
| © 2001-2009, DermAtlas | Image Name: | iahe_3_011009 | File Type: | jpg | |
| Diagnosis: | INFANTILE ACUTE HEMORRHAGIC EDEMA / HENOCH SCHONLEIN PURPURA | Category: | reactive erythema / purpura | ||
| Body Site: | arm / elbow | Age: | 26 months | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | round red purpuric papules and plaques some forming large confluent and reticulated plaques on the limbs, buttocks and face with edema of the ears and extremities, particularly the hands and feet | ||||
| Comments: | This 26 month old boy developed widespread hemorrhagic papules and plaques on the extremities, buttocks and face with edema of the ears, hands and feet. Histopathologic examination of the skin showed a leukocytoclastic vasculitis and direct immunofluorescence (DIF) was negative. The skin lesions healed in 8 days without necrosis. The morphology, histopathology and course of the skin rash with negative DIF and lack of systemic disease is most consistent with infantile acute hemorrhagic edema (IAHE). Although originally described in the United States in 1913, IAHE has been generally ignored in the English literature. Unlike Henoch-Schonlein purpura, IAHE occurs in children under 2 year old and is not associated with serious visceral disease. For a good review see J Am Acad Dermatol 1991;24:17-22. (Click on the diagnosis for Pubmed search.) | ||||
| Related Images: | All related Images iahe_2_011009 iahe_1_011009 | ||||
| © 2001-2009, DermAtlas | Image Name: | iahe_1_011009 | File Type: | jpg | |
| Diagnosis: | INFANTILE ACUTE HEMORRHAGIC EDEMA / HENOCH SCHONLEIN PURPURA | Category: | reactive erythema / purpura / collagen vascular disease | ||
| Body Site: | face | Age: | 26 months | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | round red purpuric papules and plaques some forming large confluent and reticulated plaques on the limbs, buttocks and face with edema of the ears and extremities, particularly the hands and feet | ||||
| Comments: | This 26 month old boy developed widespread hemorrhagic papules and plaques on the extremities, buttocks and face with edema of the ears, hands and feet. Histopathologic examination of the skin showed a leukocytoclastic vasculitis and direct immunofluorescence (DIF) was negative. The skin lesions healed in 8 days without necrosis. The morphology, histopathology and course of the skin rash with negative DIF and lack of systemic disease is most consistent with infantile acute hemorrhagic edema (IAHE). Although originally described in the United States in 1913, IAHE has been generally ignored in the English literature. Unlike Henoch-Schonlein purpura, IAHE occurs in children under 2 years old and is not associated with serious visceral disease. For a good review see J Am Acad Dermatol 1991;24:17-22. (Click on the diagnosis for Pubmed search.) | ||||
| Related Images: | All related Images iahe_2_011009 iahe_3_011009 | ||||
| © 2001-2009, DermAtlas | Image Name: | iahe_2_011009 | File Type: | jpg | |
| Diagnosis: | INFANTILE ACUTE HEMORRHAGIC EDEMA / HENOCH SCHONLEIN PURPURA | Category: | reactive erythema / purpura / collagen vascular disease | ||
| Body Site: | buttock / thigh leg | Age: | 26 months | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | round red purpuric papules and plaques some forming large confluent and reticulated plaques on the limbs, buttocks and face with edema of the ears and extremities, particularly the hands and feet | ||||
| Comments: | This 26 month old boy developed widespread hemorrhagic papules and plaques on the extremities, buttocks and face with edema of the ears, hands and feet. Histopathologic examination of the skin showed a leukocytoclastic vasculitis and direct immunofluorescence (DIF) was negative. The skin lesions healed in 8 days without necrosis. The morphology, histopathology and course of the skin rash with negative DIF and lack of systemic disease is most consistent with infantile acute hemorrhagic edema (IAHE). Although originally described in the United States in 1913, IAHE has been generally ignored in the English literature. Unlike Henoch-Schonlein purpura, IAHE occurs in children under 2 years old and is not associated with serious visceral disease. For a good review see J Am Acad Dermatol 1991;24:17-22. (Click on the diagnosis for Pubmed search.) | ||||
| Related Images: | All related Images iahe_1_011009 iahe_3_011009 | ||||
| © 2001-2009, DermAtlas | Image Name: | papillitis_1_010930 | File Type: | jpg | |
| Diagnosis: | PAPILLITIS, ERUPTIVE FAMILIAL LINGUAL / STRAWBERRY TONGUE | Category: | mucous membrane disorders | ||
| Body Site: | tongue | Age: | 8 years | ||
| Contributor: | Patrice Plantin, MD | ||||
| Description: | diffuse symmetric red papules on the tip and dorsolateral tongue | ||||
| Comments: | An 8 year old girl developed painful red hypertrophic fungiform papillae on the tip and dorsolateral part of the tongue. The center of the tongue, lips, gingivae, palate, and throat appeared normal. The stomatitis lasted 1 week and followed by 2 weeks a similar eruption in her 2 year old sister. These findings correspond to "eruptive familial lingual papillitis" described by JP Lacour et al. Pediatr Dermatol 1997;14:13-6. | ||||
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