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 © 2001-2009, DermAtlas | Image Name: | acral_nevus_1_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, ACRAL / NEVUS, PIGMENTED / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | toe | Age: | 33 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | Histologic sections are of acral skin. There is a fairly symmetric cellular lesion involving the epidermis and dermis. | ||||
| Comments: | This 33 year old woman presented with a pigmented papule on her 3rd toe. It was biopsied to rule out melanoma. Acral nevi are a subset of melanocytic nevocellular nevi, which can have atypical clinical and histologic findings, but are benign. Clinically, the lesions often have irregular but sharp borders, likely due to the presence of dermatoglyphs. Histologically, they may also have atypical features. The most notorious and often striking feature is upward migration of melanocytes. This can mimic the pagetoid growth of melanoma in situ. Other features include overall symmetry, maturation with syringotropism, and lack of mitotic activity or significant cytologic atypia [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | All related Images acral_nevus_3_090401 acral_nevus_2_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | acral_nevus_2_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, ACRAL / NEVUS, PIGMENTED / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | toe | Age: | 33 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | There are large expansile nevocellular nests. There is syringotropsim of the melanocytes. Significant cytologic atpyia is not appreciated. | ||||
| Comments: | This 33 year old woman presented with a pigmented papule on her 3rd toe. It was biopsied to rule out melanoma. Acral nevi are a subset of melanocytic nevocellular nevi, which can have atypical clinical and histologic findings, but are benign. Clinically, the lesions often have irregular but sharp borders, likely due to the presence of dermatoglyphs. Histologically, they may also have atypical features. The most notorious and often striking feature is upward migration of melanocytes. This can mimic the pagetoid growth of melanoma in situ. Other features include overall symmetry, maturation with syringotropism, and lack of mitotic activity or significant cytologic atypia [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | All related Images acral_nevus_3_090401 acral_nevus_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | acral_nevus_3_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, ACRAL / NEVUS, PIGMENTED / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | toe | Age: | 33 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | The melanocytes proliferate along the junction, with foci of lentiginous growth. There are large nests, positioned along the retia. In one focus, single cells and few aggregates ascend into the epidermis. These are not cytologically atypical. | ||||
| Comments: | This 33 year old woman presented with a pigmented papule on her 3rd toe. It was biopsied to rule out melanoma. Acral nevi are a subset of melanocytic nevocellular nevi, which can have atypical clinical and histologic findings, but are benign. Clinically, the lesions often have irregular but sharp borders, likely due to the presence of dermatoglyphs. Histologically, they may also have atypical features. The most notorious and often striking feature is upward migration of melanocytes. This can mimic the pagetoid growth of melanoma in situ. Other features include overall symmetry, maturation with syringotropism, and lack of mitotic activity or significant cytologic atypia [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | All related Images acral_nevus_2_090401 acral_nevus_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | herpetic_whitlow_1_090117 | File Type: | jpg | |
| Diagnosis: | HERPES SIMPLEX VIRUS INFECTION / WHITLOW | Category: | infections and infestations / vesiculobullous eruptions | ||
| Body Site: | foot / toe | Age: | 4 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | swollen red toe with clustered discrete and confluent uniform 3 mm vesicles and pustules with some crusting and erythema streaking over the top of the foot | ||||
| Comments: | This healthy 4-year-old girl developed a nontender swollen red toe with clustered vesicles and pustules. Viral culture was positive for Herpes simplex virus. She was treated with parenteral acyclovir for 2 days and completed a 7 day course orally. The lesions improved within a week with decreased edema and erythematous. The vesicles and crusts dried and peeled. | ||||
| Related Images: | All related Images herpetic_whitlow_5_090117 herpetic_whitlow_4_090117 herpetic_whitlow_3_090117 herpetic_whitlow_2_090117 | ||||
 © 2001-2009, DermAtlas | Image Name: | herpetic_whitlow_2_090117 | File Type: | jpg | |
| Diagnosis: | HERPES SIMPLEX VIRUS INFECTION / WHITLOW | Category: | infections and infestations / vesiculobullous eruptions | ||
| Body Site: | foot / toe | Age: | 4 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | swollen red toe with clustered discrete and confluent uniform 3 mm vesicles and pustules with some crusting and erythema streaking over the top of the foot | ||||
| Comments: | This healthy 4-year-old girl developed a nontender swollen red toe with clustered vesicles and pustules. Viral culture was positive for Herpes simplex virus. She was treated with parenteral acyclovir for 2 days and completed a 7 day course orally. The lesions improved within a week with decreased edema and erythematous. The vesicles and crusts dried and peeled. | ||||
| Related Images: | All related Images herpetic_whitlow_5_090117 herpetic_whitlow_4_090117 herpetic_whitlow_3_090117 herpetic_whitlow_1_090117 | ||||
 © 2001-2009, DermAtlas | Image Name: | herpetic_whitlow_3_090117 | File Type: | jpg | |
| Diagnosis: | HERPES SIMPLEX VIRUS INFECTION / WHITLOW | Category: | infections and infestations / vesiculobullous eruptions | ||
| Body Site: | foot / toe | Age: | 4 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | swollen red toe with clustered discrete and confluent uniform 3 mm vesicles and pustules with some crusting and erythema streaking over the top of the foot | ||||
| Comments: | This healthy 4-year-old girl developed a nontender swollen red toe with clustered vesicles and pustules. Viral culture was positive for Herpes simplex virus. She was treated with parenteral acyclovir for 2 days and completed a 7 day course orally. The lesions improved within a week with decreased edema and erythematous. The vesicles and crusts dried and peeled. | ||||
| Related Images: | All related Images herpetic_whitlow_5_090117 herpetic_whitlow_4_090117 herpetic_whitlow_2_090117 herpetic_whitlow_1_090117 | ||||
 © 2001-2009, DermAtlas | Image Name: | herpetic_whitlow_4_090117 | File Type: | jpg | |
| Diagnosis: | HERPES SIMPLEX VIRUS INFECTION / WHITLOW | Category: | infections and infestations / vesiculobullous eruptions | ||
| Body Site: | foot / toe | Age: | 4 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | swollen red toe with clustered discrete and confluent uniform 3 mm vesicles and pustules with some crusting and erythema streaking over the top of the foot | ||||
| Comments: | This healthy 4-year-old girl developed a nontender swollen red toe with clustered vesicles and pustules. Viral culture was positive for Herpes simplex virus. She was treated with parenteral acyclovir for 2 days and completed a 7 day course orally. The lesions improved within a week with decreased edema and erythematous. The vesicles and crusts dried and peeled. | ||||
| Related Images: | All related Images herpetic_whitlow_5_090117 herpetic_whitlow_3_090117 herpetic_whitlow_2_090117 herpetic_whitlow_1_090117 | ||||
 © 2001-2009, DermAtlas | Image Name: | herpetic_whitlow_5_090117 | File Type: | jpg | |
| Diagnosis: | HERPES SIMPLEX VIRUS INFECTION / WHITLOW | Category: | infections and infestations / vesiculobullous eruptions | ||
| Body Site: | foot / toe | Age: | 4 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | swollen red toe with clustered discrete and confluent uniform 3 mm vesicles and pustules with some crusting and erythema streaking over the top of the foot | ||||
| Comments: | This healthy 4-year-old girl developed a nontender swollen red toe with clustered vesicles and pustules. Viral culture was positive for Herpes simplex virus. She was treated with parenteral acyclovir for 2 days and completed a 7 day course orally. The lesions improved within a week with decreased edema and erythematous. The vesicles and crusts dried and peeled. | ||||
| Related Images: | All related Images herpetic_whitlow_4_090117 herpetic_whitlow_3_090117 herpetic_whitlow_2_090117 herpetic_whitlow_1_090117 | ||||
 © 2001-2009, DermAtlas | Image Name: | acquired_digital_fibrokeratoma_1_081210 | File Type: | jpg | |
| Diagnosis: | DIGITAL FIBROKERATOMA, ACQUIRED | Category: | neoplasm, fibrohistiocytic / neoplasm, benign | ||
| Body Site: | toe / foot | Age: | 29 years | ||
| Contributor: | Yashpal Manchanda, MD | ||||
| Description: | 1 cm scaly skin colored nodule | ||||
| Comments: | This 29-year-old man complained of an asymptomatic growth on his right fourth toe for 2 years. A biopsy confirmed the diagnosis of acquired digital fibrokeratoma. | ||||
 © 2001-2009, DermAtlas | Image Name: | traumatized_wart_2_080823 | File Type: | jpg | |
| Diagnosis: | NEVUS, PIGMENTED / HEMORRHAGE / TACHE NOIR / TRAUMA | Category: | hyperpigmentation / purpura | ||
| Body Site: | toe | Age: | 40 years | ||
| Contributor: | Sherry Guralnick Cohen, CRNP-F | ||||
| Description: | 1 X 0.6 cm brown plaque studded with multiple tiny black papules | ||||
| Comments: | This dark pigmented lesion on the right second toe was initially diagnosed as a melanoma. On closer observation with magnification and dermoscopy, it was apparent that this was a traumatized nevus. Biopsy revealed an innocent compound pigmented nevus with hemorrhage. | ||||
| Related Images: | traumatized_wart_1_080823 | ||||
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