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DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_4_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_2_090818  papular_urticaria_3_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_3_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_2_090818  papular_urticaria_4_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_2_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_3_090818  papular_urticaria_4_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_1_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_2_090818  papular_urticaria_3_090818  papular_urticaria_4_090818 

DermAtlas: ANKLE - pyoderma gangrenosum
© 2001-2009, DermAtlas
Image Name: pyoderma_ganrenosum_1_090617   File Type: jpg
Diagnosis: PYODERMA GANGRENOSUM   Category: ulcer /
reactive erythema
Body Site: ankle / foot / foot   Age: 12 years
Contributor: Yung Kelly    
Description: healing ulcers and scars with surrounding erythema and hyperpigmentation
Comments: This 12-year-old boy had recurrent and persistent painful ulcers on his leg and ankle. He did improve on oral prednisone, buit when the medication was tapered new lesions appeared on the ankle. He had no history of inflammatory bowel disease, underlying malignancy, sarcoidosis, or other chronic illness. An extensive medical and laboratory evaluation ( ANA, anti-dsDNA, anti-ENA, ANCA, and Cryoglobulin)was negative .

DermAtlas: Histology - angioleiomyoma
© 2001-2009, DermAtlas
Image Name: angioleiomyoma_1_090401   File Type: jpg
Diagnosis: ANGIOLEIOMYOMA   Category: neoplasm, muscle /
neoplasm, benign
Body Site: ankle   Age: 35 years
Contributor: Greg Hosler, MD, PhD    
Description: There is a well-circumscribed solitary nodule within the deep dermis on acral skin. It is brightly eosinophilic and consists of spindled cells.
Comments: This 35 year old woman had a long-standing solitary mass on her ankle. It was mildly painful. It was biopsied as a possible cyst or glomus tumor. Angioleiomyomas are the "pink balls in the dermis" and also part of the painful skin lesion mneumonic. This is a typical example with a very distinctive look, arising from the deep dermal and subcutaneous vessel walls. The vessels may not be a prominent component as they are often collapsed. Some variants are cellular. These are easily differentiated from piloleiomyomas, which at low power ramify through collagen bundles instead of having circumscription.
Related Images: angioleiomyoma_2_090401 

DermAtlas: Histology - angioleiomyoma
© 2001-2009, DermAtlas
Image Name: angioleiomyoma_2_090401   File Type: jpg
Diagnosis: ANGIOLEIOMYOMA   Category: neoplasm, muscle /
neoplasm, benign
Body Site: ankle   Age: 35 years
Contributor: Greg Hosler, MD, PhD    
Description: The cells have short, blunt-ended nuclei and abundant pink cytoplasm. When cut in cross-section, there are perinuclear vacuoles. The vessels are fairly inconspicuous. There is no cytologic atypia or mitotic activity.
Comments: This 35 year old woman had a long-standing solitary mass on her ankle. It was mildly painful. It was biopsied as a possible cyst or glomus tumor. Angioleiomyomas are the "pink balls in the dermis" and also part of the painful skin lesion mneumonic. This is a typical example with a very distinctive look, arising from the deep dermal and subcutaneous vessel walls. The vessels may not be a prominent component as they are often collapsed. Some variants are cellular. These are easily differentiated from piloleiomyomas, which at low power ramify through collagen bundles instead of having circumscription.
Related Images: angioleiomyoma_1_090401 

DermAtlas: ANKLE - leishmaniasis
© 2001-2009, DermAtlas
Image Name: Leishmaniasis_1_090304   File Type: jpg
Diagnosis: LEISHMANIASIS   Category: ulcer /
tropical medicine /
infections and infestations
Body Site: ankle
foot / leg
  Age: 21 years
Contributor: Brock Andersen, MD    
Description: 1.5 cm ulcerated indurated plaque with surrounding erythema and a smaller satellite lesions
Comments: This 21-year-old Marine was evaluated during his second deployment for a non-healing ulcer for 4 weeks. He was in an area with high concentration of sand flies 9 months prior to presentation. The eruption started as a blister but quickly developed into an itchy ulcer with the satellite lesions. The lesion was slightly indurated at the borders with surrounding erythema and edema. Biopsy confirmed Leishmaniasis, and the ulcer healed with supportive measures (for itching) in 5 months.

DermAtlas: FOOT - scabies
© 2001-2009, DermAtlas
Image Name: Scabies_1_081007   File Type: jpg
Diagnosis: SCABIES /
BURROW
  Category: infections and infestations
Body Site: foot / ankle
toe
  Age: 5 months
Contributor: Will Sorey, MD    
Description: generalized red papules and pustules many of which are elongated with overlying linear scale
Comments: This 5-month-old was covered with scaly papules and pustules with most prominent involvement of the feet. Her mother had similar lesions with generalized excoriations. Note that many of the papules and pustules are elongated typical of burrows. This case was prepared by University of Mississippi year 4 medical student Yakeyla Nave.

DermAtlas: Histology - drug reaction
© 2001-2009, DermAtlas
Image Name: chemotherapy_1_080801   File Type: jpg
Diagnosis: DRUG REACTION   Category: drug reaction /
Iatrogenic disorders, child abuse,
Body Site: ankle / foot
arm
  Age: 60 years
Contributor: Greg Hosler, MD, PhD    
Description: There is keratinocytic atypia and mild nuclear pleomorphism with scattered dyskeratotic cells. The dysplastic change of an actinic keratosis or Bowen's disease is not seen.
Comments: This 60 year old man was on Avastin, Ioxitane, and Zometa for prostate cancer, all of which have been reported to cause cutaneous eruptions. He developed erythematous to violaceous hemorrhagic plaques on his extremities over two months. Chemotherapeutic drugs can cause acral erythema, hidradenitis, radiation recall dermatitis, and others. This case shows keratinocytic dysmaturation, a common finding with certain chemotherapies.

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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