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DermAtlas: LEG - nevus, epidermal
© 2001-2009, DermAtlas
Image Name: LinearNevus_1_090828   File Type: jpg
Diagnosis: NEVUS, EPIDERMAL /
NEVUS, LINEAR EPIDERMAL
  Category: linear eruptions /
neoplasm, epidermal
Body Site: leg   Age: 12 years
Contributor: Will Sorey, MD    
Description: linear warty hyperpigmented plaque
Comments: This 12-year-old boy had a linear brown warty plaque on the back of his left leg at birth.The lesion was asymptomatic and unchanged since birth. This case was prepared by senior medical student at the University of Mississippi.Sarah Conerly,

DermAtlas: TOTAL BODY - urticaria pigmentosa
© 2001-2009, DermAtlas
Image Name: urticaria_pigmentosa_1_0910005   File Type: jpg
Diagnosis: URTICARIA PIGMENTOSA /
MASTOCYTOSIS
  Category: hyperpigmentation /
lumps & bumps (plaques, nodules, tumors)
Body Site: total body / back
buttock / leg
  Age: 2 years
Contributor: Robin&Gene Stevenson    
Description: multiple disseminated golden brown leathery .05-2.5 cm papules and plaques
Comments: This healthy 2-year-old boy developed multiuple golden brown papules and plaques on his trunk and extremities. A dramatic Darier sign was readily elicited by rubbing. Lesions first began to appear at 3 months of age and peaked by 18 months of age. Although the eruption remained stable until age 6, many lesions cleared over the subsequent year. He continued to grow and develop normally.
Related Images: All related Images  urticaria_pigmentosa_4_0910005  urticaria_pigmentosa_3_0910005  urticaria_pigmentosa_2_0910005 

DermAtlas: TOTAL BODY - urticaria pigmentosa
© 2001-2009, DermAtlas
Image Name: urticaria_pigmentosa_2_0910005   File Type: jpg
Diagnosis: URTICARIA PIGMENTOSA /
MASTOCYTOSIS
  Category: hyperpigmentation /
lumps & bumps (plaques, nodules, tumors)
Body Site: total body / back
buttock / leg
  Age: 2 years
Contributor: Robin&Gene Stevenson    
Description: multiple disseminated golden brown leathery .05-2.5 cm papules and plaques
Comments: This healthy 2-year-old boy developed multiuple golden brown papules and plaques on his trunk and extremities. A dramatic Darier sign was readily elicited by rubbing. Lesions first began to appear at 3 months of age and peaked by 18 months of age. Although the eruption remained stable until age 6, many lesions cleared over the subsequent year. He continued to grow and develop normally.
Related Images: All related Images  urticaria_pigmentosa_4_0910005  urticaria_pigmentosa_3_0910005  urticaria_pigmentosa_1_0910005 

DermAtlas: TOTAL BODY - urticaria pigmentosa
© 2001-2009, DermAtlas
Image Name: urticaria_pigmentosa_3_0910005   File Type: jpg
Diagnosis: URTICARIA PIGMENTOSA /
MASTOCYTOSIS
  Category: hyperpigmentation /
lumps & bumps (plaques, nodules, tumors)
Body Site: total body / back
buttock / leg
  Age: 7 years
Contributor: Robin&Gene Stevenson    
Description: subtle residual light brown macules
Comments: At age 6 the eruption began to improve, and by his seventh birthday many lesions had resolved or flattened.
Related Images: All related Images  urticaria_pigmentosa_4_0910005  urticaria_pigmentosa_2_0910005  urticaria_pigmentosa_1_0910005 

DermAtlas: TOTAL BODY - urticaria pigmentosa
© 2001-2009, DermAtlas
Image Name: urticaria_pigmentosa_4_0910005   File Type: jpg
Diagnosis: URTICARIA PIGMENTOSA /
MASTOCYTOSIS
  Category: hyperpigmentation /
lumps & bumps (plaques, nodules, tumors)
Body Site: total body / back
buttock / leg
  Age: 7 years
Contributor: Robin&Gene Stevenson    
Description: subtle residual light brown macules
Comments: At age 6 the eruption began to improve, and by his seventh birthday many lesions had resolved or flattened.
Related Images: All related Images  urticaria_pigmentosa_3_0910005  urticaria_pigmentosa_2_0910005  urticaria_pigmentosa_1_0910005 

DermAtlas: TOTAL BODY - drug reaction, eczematous
© 2001-2009, DermAtlas
Image Name: MITOMYCIN_7_090828   File Type: jpg
Diagnosis: DRUG REACTION, ECZEMATOUS /
MITOMYCIN C DRUG REACTION
  Category: drug reaction
Body Site: total body / leg   Age: 72 years
Contributor: Andrei Botnaru    
Description: generalized red, scaly, crusted, excoriated eczematous patches
Comments: This 72-year-old man developed a generalized eczematous eruption after the fifth intravesical instillation of mitomycin C for treatment of transitional cell carcinoma of the bladder following endoscopic resection of the tumor.Repeated intravesical instillations of this alkylating agent can induce cystitis and an eczematous eruption affecting the palms, soles and face. If these effects are due to a delayed hypersensitivity with sensitization to mitomycin C occurring in the bladder, it should be possible to demonstrate antigen-presenting cells in the bladder wall. Positive patch testing in sensitized patients has been reported suggesting that the eczematous eruption most likely represents a type IV delayed hypersensitivity reaction that is mediated transvesically. Discontinuation of the drug results in clearing of the skin eruption. Dermatologists and anyone involved in the treatment of these patients should be aware of this complication of therapy. (Kunkeler L, Nieboer C, Bruynzeel DP. Type III and type IV hypersensitivity reactions due to mitomycin C.Contact Dermatitis. 2000 Feb;42(2):74-6)
Related Images: All related Images  MITOMYCIN_1_090828  MITOMYCIN_2_090828  MITOMYCIN_3_090828  MITOMYCIN_5_090828  MITOMYCIN_6_090828  MITOMYCIN_8_090828 

DermAtlas: TOTAL BODY - drug reaction, eczematous
© 2001-2009, DermAtlas
Image Name: MITOMYCIN_3_090828   File Type: jpg
Diagnosis: DRUG REACTION, ECZEMATOUS /
MITOMYCIN C DRUG REACTION
  Category: drug reaction
Body Site: total body / leg   Age: 72 years
Contributor: Andrei Botnaru    
Description: generalized red, scaly, crusted, excoriated eczematous patches
Comments: This 72-year-old man developed a generalized eczematous eruption after the fifth intravesical instillation of mitomycin C for treatment of transitional cell carcinoma of the bladder following endoscopic resection of the tumor.Repeated intravesical instillations of this alkylating agent can induce cystitis and an eczematous eruption affecting the palms, soles and face. If these effects are due to a delayed hypersensitivity with sensitization to mitomycin C occurring in the bladder, it should be possible to demonstrate antigen-presenting cells in the bladder wall. Positive patch testing in sensitized patients has been reported suggesting that the eczematous eruption most likely represents a type IV delayed hypersensitivity reaction that is mediated transvesically. Discontinuation of the drug results in clearing of the skin eruption. Dermatologists and anyone involved in the treatment of these patients should be aware of this complication of therapy. (Kunkeler L, Nieboer C, Bruynzeel DP. Type III and type IV hypersensitivity reactions due to mitomycin C.Contact Dermatitis. 2000 Feb;42(2):74-6)
Related Images: All related Images  MITOMYCIN_1_090828  MITOMYCIN_2_090828  MITOMYCIN_5_090828  MITOMYCIN_6_090828  MITOMYCIN_7_090828  MITOMYCIN_8_090828 

DermAtlas: TOTAL BODY - drug reaction, eczematous
© 2001-2009, DermAtlas
Image Name: MITOMYCIN_1_090828   File Type: jpg
Diagnosis: DRUG REACTION, ECZEMATOUS /
MITOMYCIN C DRUG REACTION
  Category: drug reaction
Body Site: total body / leg   Age: 72 years
Contributor: Andrei Botnaru    
Description: generalized red, scaly, crusted, excoriated eczematous patches
Comments: This 72-year-old man developed a generalized eczematous eruption after the fifth intravesical instillation of mitomycin C for treatment of transitional cell carcinoma of the bladder following endoscopic resection of the tumor.Repeated intravesical instillations of this alkylating agent can induce cystitis and an eczematous eruption affecting the palms, soles and face. If these effects are due to a delayed hypersensitivity with sensitization to mitomycin C occurring in the bladder, it should be possible to demonstrate antigen-presenting cells in the bladder wall. Positive patch testing in sensitized patients has been reported suggesting that the eczematous eruption most likely represents a type IV delayed hypersensitivity reaction that is mediated transvesically. Discontinuation of the drug results in clearing of the skin eruption. Dermatologists and anyone involved in the treatment of these patients should be aware of this complication of therapy. (Kunkeler L, Nieboer C, Bruynzeel DP. Type III and type IV hypersensitivity reactions due to mitomycin C.Contact Dermatitis. 2000 Feb;42(2):74-6)
Related Images: All related Images  MITOMYCIN_2_090828  MITOMYCIN_3_090828  MITOMYCIN_5_090828  MITOMYCIN_6_090828  MITOMYCIN_7_090828  MITOMYCIN_8_090828 

DermAtlas: LEG - insect bite reaction
© 2001-2009, DermAtlas
Image Name: papular_urticaria_1_090819   File Type: jpg
Diagnosis: INSECT BITE REACTION /
PAPULAR URTICARIA
  Category: environmental injury /
hypersensitivity /
linear eruptions
Body Site: leg / back   Age: 4 years
Contributor: Bernard Cohen, MD    
Description: uniform edematous papules with central crusting and hypopigmentation and peripheral hyperpigmentation grouped in a linear pattern
Comments: This healthy 4-year-old girl developed a chronic and recurrent pruritic papular eruption on exposed areas particularly the legs 6 months ago. The lesions began as edematous red papules many with a central vesicle. Scratching led to central crusting and hypopigmentation with a surrounding hyperpigmented ring.
Related Images: All related Images  papular_urticaria_3_090819  papular_urticaria_2_090819 

DermAtlas: LEG - insect bite reaction
© 2001-2009, DermAtlas
Image Name: papular_urticaria_2_090819   File Type: jpg
Diagnosis: INSECT BITE REACTION /
PAPULAR URTICARIA
  Category: environmental injury /
hypersensitivity /
linear eruptions
Body Site: leg / back   Age: 4 years
Contributor: Bernard Cohen, MD    
Description: uniform edematous papules with central crusting and hypopigmentation and peripheral hyperpigmentation grouped in a linear pattern
Comments: This healthy 4-year-old girl developed a chronic and recurrent pruritic papular eruption on exposed areas particularly the legs 6 months ago. The lesions began as edematous red papules many with a central vesicle. Scratching led to central crusting and hypopigmentation with a surrounding hyperpigmented ring.
Related Images: All related Images  papular_urticaria_3_090819  papular_urticaria_1_090819 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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