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DermAtlas: BACK - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: Staph_Scalded_Skin_1_090828   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
toxin mediated disorder
Body Site: back / neck
total body / face
  Age: 4 years
Contributor: Catherine Albert    
Description:
Comments: A 3.5-year-old girl had a 2 day history of progressive erythema on the back, neck, and face particularly around her ears. Twelve days earlier she had a mosquito bite which became secondarily infected 2 days later with the development of superficial bullae and honey-colored crusts. Two days before evaluation she developed diffuse tender red skin and low grade fevers. Although she had peeling lips, her mucous membranes were clear. She improved with anti-Staphylococcal antibiotics, and 7-10 days later experienced widespread peeling.
Related Images: All related Images  Staph_Scalded_Skin_4_090828  Staph_Scalded_Skin_3_090828  Staph_Scalded_Skin_2_090828 

DermAtlas: BACK - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: Staph_Scalded_Skin_2_090828   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
toxin mediated disorder
Body Site: back / neck
total body / face
  Age: 4 years
Contributor: Catherine Albert    
Description:
Comments: A 3.5-year-old girl had a 2 day history of progressive erythema on the back, neck, and face particularly around her ears. Twelve days earlier she had a mosquito bite which became secondarily infected 2 days later with the development of superficial bullae and honey-colored crusts. Two days before evaluation she developed diffuse tender red skin and low grade fevers. Although she had peeling lips, her mucous membranes were clear. She improved with anti-Staphylococcal antibiotics, and 7-10 days later experienced widespread peeling.
Related Images: All related Images  Staph_Scalded_Skin_4_090828  Staph_Scalded_Skin_3_090828  Staph_Scalded_Skin_1_090828 

DermAtlas: BACK - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: Staph_Scalded_Skin_3_090828   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
toxin mediated disorder
Body Site: back / neck
total body / face
  Age: 4 years
Contributor: Catherine Albert    
Description:
Comments: A 3.5-year-old girl had a 2 day history of progressive erythema on the back, neck, and face particularly around her ears. Twelve days earlier she had a mosquito bite which became secondarily infected 2 days later with the development of superficial bullae and honey-colored crusts. Two days before evaluation she developed diffuse tender red skin and low grade fevers. Although she had peeling lips, her mucous membranes were clear. She improved with anti-Staphylococcal antibiotics, and 7-10 days later experienced widespread peeling.
Related Images: All related Images  Staph_Scalded_Skin_4_090828  Staph_Scalded_Skin_2_090828  Staph_Scalded_Skin_1_090828 

DermAtlas: BACK - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: Staph_Scalded_Skin_4_090828   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
toxin mediated disorder
Body Site: back / neck
total body / face
  Age: 4 years
Contributor: Catherine Albert    
Description:
Comments: A 3.5-year-old girl had a 2 day history of progressive erythema on the back, neck, and face particularly around her ears. Twelve days earlier she had a mosquito bite which became secondarily infected 2 days later with the development of superficial bullae and honey-colored crusts. Two days before evaluation she developed diffuse tender red skin and low grade fevers. Although she had peeling lips, her mucous membranes were clear. She improved with anti-Staphylococcal antibiotics, and 7-10 days later experienced widespread peeling.
Related Images: All related Images  Staph_Scalded_Skin_3_090828  Staph_Scalded_Skin_2_090828  Staph_Scalded_Skin_1_090828 

DermAtlas: FACE - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staphylococcal_scalded_skin_syndrome_5_090120   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
reactive erythema /
vesiculobullous eruptions
Body Site: face / total body   Age: 6 months
Contributor: Bernard Cohen, MD    
Description: generalized erythema, scaling, and periorificial crusting
Comments: This healthy 6-month-old girl developed a low grade fever, incresed fussiness, and generalized erythema with scaling, crusting, and fissuring accentuated around the mouth and skin creases. An erosion appeared after her mother placed her on the examining table typical of a Nikolsky sign. Methicillin sensitive Staphylococcus aureus grew from a skin culture taken from her nares. She did well on oral antibiotics, acetominophen, and topical emollients with drying of the crusts and clearing of the erythema in 2 days and diffuse desquamation 5 days later.
Related Images: All related Images  staphylococcal_scalded_skin_syndrome_1_090120  staphylococcal_scalded_skin_syndrome_2_090120  staphylococcal_scalded_skin_syndrome_3_090120  staphylococcal_scalded_skin_syndrome_4_090120 

DermAtlas: ABDOMEN - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staphylococcal_scalded_skin_syndrome_4_090120   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
reactive erythema /
vesiculobullous eruptions
Body Site: abdomen / total body
leg
  Age: 6 months
Contributor: Bernard Cohen, MD    
Description: generalized erythema, scaling, and periorificial crusting
Comments: This healthy 6-month-old girl developed a low grade fever, incresed fussiness, and generalized erythema with scaling, crusting, and fissuring accentuated around the mouth and skin creases. An erosion appeared after her mother placed her on the examining table typical of a Nikolsky sign. Methicillin sensitive Staphylococcus aureus grew from a skin culture taken from her nares. She did well on oral antibiotics, acetominophen, and topical emollients with drying of the crusts and clearing of the erythema in 2 days and diffuse desquamation 5 days later.
Related Images: All related Images  staphylococcal_scalded_skin_syndrome_1_090120  staphylococcal_scalded_skin_syndrome_2_090120  staphylococcal_scalded_skin_syndrome_3_090120  staphylococcal_scalded_skin_syndrome_5_090120 

DermAtlas: ABDOMEN - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staphylococcal_scalded_skin_syndrome_3_090120   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
reactive erythema /
vesiculobullous eruptions
Body Site: abdomen / total body
leg
  Age: 6 months
Contributor: Bernard Cohen, MD    
Description: generalized erythema, scaling, and periorificial crusting
Comments: This healthy 6-month-old girl developed a low grade fever, incresed fussiness, and generalized erythema with scaling, crusting, and fissuring accentuated around the mouth and skin creases. An erosion appeared after her mother placed her on the examining table typical of a Nikolsky sign. Methicillin sensitive Staphylococcus aureus grew from a skin culture taken from her nares. She did well on oral antibiotics, acetominophen, and topical emollients with drying of the crusts and clearing of the erythema in 2 days and diffuse desquamation 5 days later.
Related Images: All related Images  staphylococcal_scalded_skin_syndrome_1_090120  staphylococcal_scalded_skin_syndrome_2_090120  staphylococcal_scalded_skin_syndrome_4_090120  staphylococcal_scalded_skin_syndrome_5_090120 

DermAtlas: FACE - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staphylococcal_scalded_skin_syndrome_2_090120   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
reactive erythema /
vesiculobullous eruptions
Body Site: face / total body   Age: 6 months
Contributor: Bernard Cohen, MD    
Description: generalized erythema, scaling, and periorificial crusting
Comments: This healthy 6-month-old girl developed a low grade fever, incresed fussiness, and generalized erythema with scaling, crusting, and fissuring accentuated around the mouth and skin creases. An erosion appeared after her mother placed her on the examining table typical of a Nikolsky sign. Methicillin sensitive Staphylococcus aureus grew from a skin culture taken from her nares. She did well on oral antibiotics, acetominophen, and topical emollients with drying of the crusts and clearing of the erythema in 2 days and diffuse desquamation 5 days later.
Related Images: All related Images  staphylococcal_scalded_skin_syndrome_1_090120  staphylococcal_scalded_skin_syndrome_3_090120  staphylococcal_scalded_skin_syndrome_4_090120  staphylococcal_scalded_skin_syndrome_5_090120 

DermAtlas: FACE - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staphylococcal_scalded_skin_syndrome_1_090120   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME /
STAPHYLOCOCCAL INFECTION
  Category: infections and infestations /
reactive erythema /
vesiculobullous eruptions
Body Site: face / total body   Age: 6 months
Contributor: Bernard Cohen, MD    
Description: generalized erythema, scaling, and periorificial crusting
Comments: This healthy 6-month-old girl developed a low grade fever, incresed fussiness, and generalized erythema with scaling, crusting, and fissuring accentuated around the mouth and skin creases. An erosion appeared after her mother placed her on the examining table typical of a Nikolsky sign. Methicillin sensitive Staphylococcus aureus grew from a skin culture taken from her nares. She did well on oral antibiotics, acetominophen, and topical emollients with drying of the crusts and clearing of the erythema in 2 days and diffuse desquamation 5 days later.
Related Images: All related Images  staphylococcal_scalded_skin_syndrome_2_090120  staphylococcal_scalded_skin_syndrome_3_090120  staphylococcal_scalded_skin_syndrome_4_090120  staphylococcal_scalded_skin_syndrome_5_090120 

DermAtlas: Histology - staphylococcal scalded skin syndrome
© 2001-2009, DermAtlas
Image Name: staph_scalded_skin_1_080801   File Type: jpg
Diagnosis: STAPHYLOCOCCAL SCALDED SKIN SYNDROME   Category: infections and infestations /
vesiculobullous eruptions
Body Site: buttock / back
leg / face
  Age: 15 years
Contributor: Greg Hosler, MD, PhD    
Description: There is a cleft in a subcorneal location. There is a mild inflammatory infiltrate in the superficial dermis.
Comments: This patient developed an erythematous eruption over her face, neck, and trunk, and it spread to her extremities. Denudation then followed. This patient is a little old for staphylococcal scalded skin syndrome, but it may occur in adults. The histology has a superficial blister, in a subcorneal location, caused by a toxin to desmoglein 1. Because of the pathophysiology, the histologic differential diagnosis includes pemphigus foliaceus and bullous impetigo. SSSS is usually paucicellular, moreso than in this case, but inflammation may ramp up in older lesions.
Related Images: staph_scalded_skin_2_080801 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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