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| © 2001-2009, DermAtlas | Image Name: | dle_1_070501 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / hair disorders / cutaneous sign of systemic disease | ||
| Body Site: | scalp | Age: | 55 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | The epidermis is mildly atrophic with dilated follicles and follicular plugging. An inflammatory infiltrate is also seen, showing a superficial and deep perivascular pattern. There is orthokeratotic hyperkeratosis. | ||||
| Comments: | This is a typical example of discoid lupus erythematosus in the context of scarring alopecia. The differential diagnosis includes the other cicatricial alopecias, such as lichen planopilaris. This biopsy shows a deeper, more intense infiltrate than typically seen with LPP, although it can be difficult to differentiate at times. In tough cases, direct immunofluorescence studies can help. | ||||
| Related Images: | dle_2_070501 | ||||
| © 2001-2009, DermAtlas | Image Name: | dle_2_070501 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / hair disorders / cutaneous sign of systemic disease | ||
| Body Site: | scalp | Age: | 55 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | The epidermis shows basilar vacuolopathy and a thickened eosinophilic basement membrane. There is also pigment incontinence in the papillary dermis. | ||||
| Comments: | This is a typical example of discoid lupus erythematosus in the context of scarring alopecia. The differential diagnosis includes the other cicatricial alopecias, such as lichen planopilaris. This biopsy shows a deeper, more intense infiltrate than typically seen with LPP, although it can be difficult to differentiate at times. In tough cases, direct immunofluorescence studies can help. | ||||
| Related Images: | dle_1_070501 | ||||
| © 2001-2009, DermAtlas | Image Name: | Lupus_Erythematousus_1_060407 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / photosensitivity, photoexacerbated | ||
| Body Site: | face / cheek face | Age: | 48 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | telangiectatis papules and plaques with erythema, crusting, and atrophy | ||||
| Comments: | This 48-year-old woman had discoid lesions for over 10 years with lesions restricted to sun exposed sites. She had large areas of scarring alopecia. | ||||
| Related Images: | All related Images Lupus_Erythematousus_3_060407 Lupus_Erythematousus_2_060407 | ||||
| © 2001-2009, DermAtlas | Image Name: | Lupus_Erythematousus_2_060407 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / photosensitivity, photoexacerbated | ||
| Body Site: | scalp / face | Age: | 48 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | red scaly atrophic and fibrotic hairless plaque | ||||
| Comments: | This 48-year-old woman had discoid lesions for over 10 years with lesions restricted to sun exposed sites. She had large areas of scarring alopecia. | ||||
| Related Images: | All related Images Lupus_Erythematousus_3_060407 Lupus_Erythematousus_1_060407 | ||||
| © 2001-2009, DermAtlas | Image Name: | Lupus_Erythematousus_3_060407 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / photosensitivity, photoexacerbated | ||
| Body Site: | scalp / face | Age: | 48 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | red scaly atrophic and fibrotic hairless plaque | ||||
| Comments: | This 48-year-old woman had discoid lesions for over 10 years with lesions restricted to sun exposed sites. She had large areas of scarring alopecia. | ||||
| Related Images: | All related Images Lupus_Erythematousus_2_060407 Lupus_Erythematousus_1_060407 | ||||
| © 2001-2009, DermAtlas | Image Name: | discoid_lupus_1_050831 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, DISCOID / LUPUS ERYTHEMATOSUS, SYSTEMIC / LUPUS ERYTHEMATOSUS | Category: | cutaneous sign of systemic disease / collagen vascular disease / hyperpigmentation / photosensitivity, photoexacerbated | ||
| Body Site: | ear / face scalp | Age: | 15 years | ||
| Contributor: | Will Sorey, MD | ||||
| Description: | symmetric hyperpigmented plaques with scale, central hypopigmentation/depigmentation, follicular plugging, and atrophy | ||||
| Comments: | This adolescent girl had typical discoid lesion on her scalp, face, and ears associated with mild arthopathy and occasional fevers. | ||||
| © 2001-2009, DermAtlas | Image Name: | lupus_erythematosus_6_041024 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / atrophy / photosensitivity, photoexacerbated | ||
| Body Site: | face / nose cheek | Age: | 30 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | symmetric violaceous round and annular confluent plaques with central crusting and atrophy | ||||
| Comments: | This 30-year-old man complained of disfiguring lesions on the face, scalp and sun exposed areas of the chest, back, and arms. The eruption worsened in summer but improved with oral corticosteroids. He also had scarring alopecia. | ||||
| Related Images: | All related Images lupus_erythematosus_1_041024 lupus_erythematosus_2_041024 lupus_erythematosus_3_041024 lupus_erythematosus_4_041024 lupus_erythematosus_5_041024 | ||||
| © 2001-2009, DermAtlas | Image Name: | lupus_erythematosus_5_041024 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / atrophy / photosensitivity, photoexacerbated | ||
| Body Site: | face / nose cheek | Age: | 30 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | symmetric violaceous round and annular confluent plaques with central crusting and atrophy | ||||
| Comments: | This 30-year-old man complained of disfiguring lesions on the face, scalp and sun exposed areas of the chest, back, and arms. The eruption worsened in summer but improved with oral corticosteroids. He also had scarring alopecia. | ||||
| Related Images: | All related Images lupus_erythematosus_1_041024 lupus_erythematosus_2_041024 lupus_erythematosus_3_041024 lupus_erythematosus_4_041024 lupus_erythematosus_6_041024 | ||||
| © 2001-2009, DermAtlas | Image Name: | lupus_erythematosus_4_041024 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / atrophy / photosensitivity, photoexacerbated | ||
| Body Site: | ear | Age: | 30 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | violaceous and hyperpigmented plaques with central atrophy and hypopigmentation | ||||
| Comments: | This 30-year-old man complained of disfiguring lesions on the face, scalp and sun exposed areas of the chest, back, and arms. The eruption worsened in summer but improved with oral corticosteroids. He also had scarring alopecia. | ||||
| Related Images: | All related Images lupus_erythematosus_1_041024 lupus_erythematosus_2_041024 lupus_erythematosus_3_041024 lupus_erythematosus_5_041024 lupus_erythematosus_6_041024 | ||||
| © 2001-2009, DermAtlas | Image Name: | lupus_erythematosus_3_041024 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DISCOID | Category: | collagen vascular disease / atrophy / photosensitivity, photoexacerbated | ||
| Body Site: | ear | Age: | 30 years | ||
| Contributor: | Kosman Sadek Zikry, MD | ||||
| Description: | violaceous and hyperpigmented plaques with central atrophy and hypopigmentation | ||||
| Comments: | This 30-year-old man complained of disfiguring lesions on the face, scalp and sun exposed areas of the chest, back, and arms. The eruption worsened in summer but improved with oral corticosteroids. He also had scarring alopecia. | ||||
| Related Images: | All related Images lupus_erythematosus_1_041024 lupus_erythematosus_2_041024 lupus_erythematosus_4_041024 lupus_erythematosus_5_041024 lupus_erythematosus_6_041024 | ||||
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