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 © 2001-2009, DermAtlas | Image Name: | sarcoidosis_tattoo_1_090828 | File Type: | jpg | |
| Diagnosis: | SARCOIDOSIS / TATTOO / LUPUS PERNIO / TATTOO COMPLICATION | Category: | cutaneous sign of systemic disease / granulomatous disorder | ||
| Body Site: | back / face | Age: | 45 years | ||
| Contributor: | L. Katie Morrison | ||||
| Description: | grouped dark brown 2-4 mm flat topped papules | ||||
| Comments: | This 45-year-old woman developed progressive infiltrative papules over the last 2 months within an old tattoo. Over the last 6 months violaceous beaded papules and nodules appeared on her nose and cheeks. A biopsy of a papule in the tattoo showed sarcoidal granulomas. | ||||
 © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_1_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
 © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_2_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
 © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_3_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_1_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Adrianna Jackson | ||||
| Description: | firm rubbern non-pitting edema with surrounding red papules and pustules | ||||
| Comments: | This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently. | ||||
| Related Images: | All related Images crohn_disease_6_090905 crohn_disease_5_090905 crohn_disease_4_090905 crohn_disease_3_090905 crohn_disease_2_090905 | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_2_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Adrianna Jackson | ||||
| Description: | firm rubbern non-pitting edema with surrounding red papules and pustules | ||||
| Comments: | This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently. | ||||
| Related Images: | All related Images crohn_disease_6_090905 crohn_disease_5_090905 crohn_disease_4_090905 crohn_disease_3_090905 crohn_disease_1_090905 | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_3_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Adrianna Jackson | ||||
| Description: | firm rubbern non-pitting edema with surrounding red papules and pustules | ||||
| Comments: | This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently. | ||||
| Related Images: | All related Images crohn_disease_6_090905 crohn_disease_5_090905 crohn_disease_4_090905 crohn_disease_2_090905 crohn_disease_1_090905 | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_4_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Jakki Junkins-Hopkins | ||||
| Description: | fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis. | ||||
| Comments: | The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative. | ||||
| Related Images: | All related Images crohn_disease_6_090905 crohn_disease_5_090905 crohn_disease_3_090905 crohn_disease_2_090905 crohn_disease_1_090905 | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_5_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Jakki Junkins-Hopkins | ||||
| Description: | fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis. | ||||
| Comments: | The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative. | ||||
| Related Images: | All related Images crohn_disease_6_090905 crohn_disease_4_090905 crohn_disease_3_090905 crohn_disease_2_090905 crohn_disease_1_090905 | ||||
 © 2001-2009, DermAtlas | Image Name: | crohn_disease_6_090905 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / INFLAMMATORY BOWEL DISEASE | Category: | granulomatous disorder / gastrointestinal disorder / cutaneous sign of systemic disease | ||
| Body Site: | genital / scrotum penis / perineum diaper area / groin | Age: | 5 years | ||
| Contributor: | Jakki Junkins-Hopkins | ||||
| Description: | fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis. | ||||
| Comments: | The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative. | ||||
| Related Images: | All related Images crohn_disease_5_090905 crohn_disease_4_090905 crohn_disease_3_090905 crohn_disease_2_090905 crohn_disease_1_090905 | ||||
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    Books by the Dermatlas Editors | © DermAtlas, Johns Hopkins University; 2000-2009 |
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