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DermAtlas: TOTAL BODY - hypereosinophilic syndrome
© 2001-2009, DermAtlas
Image Name: hypereosinophilic_syndrome_1_090821   File Type: jpg
Diagnosis: HYPEREOSINOPHILIC SYNDROME   Category: reactive erythema /
cutaneous sign of systemic disease /
hypersensitivity
Body Site: total body / arm   Age: 40 years
Contributors: Daniel Chang
Chris Bengson
   
Description: scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers
Comments: A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms.

DermAtlas: TOTAL BODY - hypereosinophilic syndrome
© 2001-2009, DermAtlas
Image Name: hypereosinophilic_syndrome_2_090821   File Type: jpg
Diagnosis: HYPEREOSINOPHILIC SYNDROME   Category: reactive erythema /
cutaneous sign of systemic disease /
hypersensitivity
Body Site: total body / arm   Age: 40 years
Contributors: Daniel Chang
Chris Bengson
   
Description: scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers
Comments: A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms.

DermAtlas: TOTAL BODY - hypereosinophilic syndrome
© 2001-2009, DermAtlas
Image Name: hypereosinophilic_syndrome_3_090821   File Type: jpg
Diagnosis: HYPEREOSINOPHILIC SYNDROME   Category: reactive erythema /
cutaneous sign of systemic disease /
hypersensitivity
Body Site: total body / arm   Age: 40 years
Contributors: Daniel Chang
Chris Bengson
   
Description: scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers
Comments: A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms.

DermAtlas: LEG - insect bite reaction
© 2001-2009, DermAtlas
Image Name: papular_urticaria_1_090819   File Type: jpg
Diagnosis: INSECT BITE REACTION /
PAPULAR URTICARIA
  Category: environmental injury /
hypersensitivity /
linear eruptions
Body Site: leg / back   Age: 4 years
Contributor: Bernard Cohen, MD    
Description: uniform edematous papules with central crusting and hypopigmentation and peripheral hyperpigmentation grouped in a linear pattern
Comments: This healthy 4-year-old girl developed a chronic and recurrent pruritic papular eruption on exposed areas particularly the legs 6 months ago. The lesions began as edematous red papules many with a central vesicle. Scratching led to central crusting and hypopigmentation with a surrounding hyperpigmented ring.
Related Images: All related Images  papular_urticaria_3_090819  papular_urticaria_2_090819 

DermAtlas: LEG - insect bite reaction
© 2001-2009, DermAtlas
Image Name: papular_urticaria_2_090819   File Type: jpg
Diagnosis: INSECT BITE REACTION /
PAPULAR URTICARIA
  Category: environmental injury /
hypersensitivity /
linear eruptions
Body Site: leg / back   Age: 4 years
Contributor: Bernard Cohen, MD    
Description: uniform edematous papules with central crusting and hypopigmentation and peripheral hyperpigmentation grouped in a linear pattern
Comments: This healthy 4-year-old girl developed a chronic and recurrent pruritic papular eruption on exposed areas particularly the legs 6 months ago. The lesions began as edematous red papules many with a central vesicle. Scratching led to central crusting and hypopigmentation with a surrounding hyperpigmented ring.
Related Images: All related Images  papular_urticaria_3_090819  papular_urticaria_1_090819 

DermAtlas: LEG - insect bite reaction
© 2001-2009, DermAtlas
Image Name: papular_urticaria_3_090819   File Type: jpg
Diagnosis: INSECT BITE REACTION /
PAPULAR URTICARIA
  Category: environmental injury /
hypersensitivity /
linear eruptions
Body Site: leg / back   Age: 4 years
Contributor: Bernard Cohen, MD    
Description: uniform edematous papules with central crusting and hypopigmentation and peripheral hyperpigmentation grouped in a linear pattern
Comments: This healthy 4-year-old girl developed a chronic and recurrent pruritic papular eruption on exposed areas particularly the legs 6 months ago. The lesions began as edematous red papules many with a central vesicle. Scratching led to central crusting and hypopigmentation with a surrounding hyperpigmented ring.
Related Images: All related Images  papular_urticaria_2_090819  papular_urticaria_1_090819 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_4_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_2_090818  papular_urticaria_3_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_3_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_2_090818  papular_urticaria_4_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_2_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_1_090818  papular_urticaria_3_090818  papular_urticaria_4_090818 

DermAtlas: FOOT - papular urticaria
© 2001-2009, DermAtlas
Image Name: papular_urticaria_1_090818   File Type: jpg
Diagnosis: PAPULAR URTICARIA /
INSECT BITE REACTION
  Category: environmental injury /
hypersensitivity
Body Site: foot / ankle   Age: 26 years
Contributor: Bernard Cohen, MD    
Description:
Comments: This healthy young adult developed an intensely pruritic eruption on his feet after walking barefoot in the garden 3 days ago. Note the uniformity of the fixed edematous papules with surrounding pallor and the organization of lesions in a linear pattern.
Related Images: All related Images  papular_urticaria_2_090818  papular_urticaria_3_090818  papular_urticaria_4_090818 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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