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| © 2001-2009, DermAtlas | Image Name: | Linea_ IgA_Dermatosis_1_081210 | File Type: | jpg | |
| Diagnosis: | LINEAR IGA DERMATOSIS | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | forearm / arm | Age: | 30 years | ||
| Contributor: | Aaisha Khan, MBBS | ||||
| Description: | vesicles and bullae some on a red base and many forming rings typical of the string of pearls sign | ||||
| Comments: | This healthy 30-year-old woman developed bullae on her arms and neck. She had a similar eruption one month ago which cleared with oral steroids. A skin biopsy showed the typical changes of linear IgA bullous dermatosis. | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_1_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | arm / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_2_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | back / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_3_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | arm / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_4_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | leg / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_5_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | leg / total body thigh / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_6_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | arm / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis. | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_7_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | arm / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis. | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_8_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | BULLOUS_PEMPHIGOID_8_080902 | File Type: | jpg | |
| Diagnosis: | BULLOUS PEMPHIGOID | Category: | vesiculobullous eruptions, immunobullous / vesiculobullous eruptions | ||
| Body Site: | arm / total body / arm | Age: | 82 years | ||
| Contributor: | Katsuya Hisamichi, MD | ||||
| Description: | There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis. | ||||
| Comments: | An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180. | ||||
| Related Images: | All related Images BULLOUS_PEMPHIGOID_7_080902 BULLOUS_PEMPHIGOID_6_080902 BULLOUS_PEMPHIGOID_5_080902 BULLOUS_PEMPHIGOID_4_080902 BULLOUS_PEMPHIGOID_3_080902 BULLOUS_PEMPHIGOID_2_080902 BULLOUS_PEMPHIGOID_1_080902 | ||||
| © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_5_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / chest / abdomen | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
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