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DermAtlas: FOREARM - linear IgA dermatosis
© 2001-2009, DermAtlas
Image Name: Linea_ IgA_Dermatosis_1_081210   File Type: jpg
Diagnosis: LINEAR IGA DERMATOSIS   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: forearm / arm   Age: 30 years
Contributor: Aaisha Khan, MBBS    
Description: vesicles and bullae some on a red base and many forming rings typical of the string of pearls sign
Comments: This healthy 30-year-old woman developed bullae on her arms and neck. She had a similar eruption one month ago which cleared with oral steroids. A skin biopsy showed the typical changes of linear IgA bullous dermatosis.

DermAtlas: ARM - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_1_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: arm / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902 

DermAtlas: BACK - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_2_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: back / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: ARM - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_3_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: arm / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: LEG - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_4_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: leg / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: LEG - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_5_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: leg / total body
thigh / arm
  Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: vesicles, bullae, and crusts with some arising on normal appearing skin and some on an erythematous base
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: Histology - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_6_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: arm / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis.
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: Histology - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_7_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: arm / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis.
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_8_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: Histology - bullous pemphigoid
© 2001-2009, DermAtlas
Image Name: BULLOUS_PEMPHIGOID_8_080902   File Type: jpg
Diagnosis: BULLOUS PEMPHIGOID   Category: vesiculobullous eruptions, immunobullous /
vesiculobullous eruptions
Body Site: arm / total body / arm   Age: 82 years
Contributor: Katsuya Hisamichi, MD    
Description: There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis.
Comments: An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.
Related Images: All related Images  BULLOUS_PEMPHIGOID_7_080902  BULLOUS_PEMPHIGOID_6_080902  BULLOUS_PEMPHIGOID_5_080902  BULLOUS_PEMPHIGOID_4_080902  BULLOUS_PEMPHIGOID_3_080902  BULLOUS_PEMPHIGOID_2_080902  BULLOUS_PEMPHIGOID_1_080902 

DermAtlas: ARM - dermatitis herpetiformis
© 2001-2009, DermAtlas
Image Name: dermatisis_herpetiformis_5_080906   File Type: jpg
Diagnosis: DERMATITIS HERPETIFORMIS   Category: vesiculobullous eruptions /
vesiculobullous eruptions, immunobullous
Body Site: arm / chest / abdomen   Age: 24 years
Contributor: Bernard Cohen, MD    
Description: widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts
Comments: This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction.
Related Images: All related Images  dermatisis_herpetiformis_6_080906  dermatisis_herpetiformis_1_080906  dermatisis_herpetiformis_2_080906  dermatisis_herpetiformis_3_080906  dermatisis_herpetiformis_4_080906 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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