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| © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_1_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
| © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_2_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
| © 2001-2009, DermAtlas | Image Name: | hypereosinophilic_syndrome_3_090821 | File Type: | jpg | |
| Diagnosis: | HYPEREOSINOPHILIC SYNDROME | Category: | reactive erythema / cutaneous sign of systemic disease / hypersensitivity | ||
| Body Site: | total body / arm | Age: | 40 years | ||
| Contributors: | Daniel Chang Chris Bengson | ||||
| Description: | scattered widely disseminated 0.5-1.5 cm red plaques with dusky centers | ||||
| Comments: | A 40-year-old woman, who was diagnosed with hypereosinophilic syndrome, was admitted on multiple occasions for angioedema of face, throat, hands, and legs, diffuse abdominal pain, and urticarial edematous plaques on her arms, trunk, and thighs. She complained of itching and then burning pain in skin lesions which persisted for 2-3 days and recurred episodically. Acute symptoms were controlled with high dose oral steroids and antihistamines. The hypereosinophilic syndromes are a heterogeneous group of disorders characterized by three common features: peripheral eosinophil count of > 1500/µL for longer than six months, evidence of end organ involvement (excluding benign eosinophilia), and absence of other causes of eosinophilia (drugs, parasites, malignancy). Skin involvement is seen in 50% of patients. Typical cutaneous features include urticaria and angioedema as well as fixed urticarial papules and plaques. Treatment of the eosinophilia usually results in improvement in cutaneous and systemic symptoms. | ||||
| © 2001-2009, DermAtlas | Image Name: | pyoderma_ganrenosum_1_090617 | File Type: | jpg | |
| Diagnosis: | PYODERMA GANGRENOSUM | Category: | ulcer / reactive erythema | ||
| Body Site: | ankle / foot / foot | Age: | 12 years | ||
| Contributor: | Yung Kelly | ||||
| Description: | healing ulcers and scars with surrounding erythema and hyperpigmentation | ||||
| Comments: | This 12-year-old boy had recurrent and persistent painful ulcers on his leg and ankle. He did improve on oral prednisone, buit when the medication was tapered new lesions appeared on the ankle. He had no history of inflammatory bowel disease, underlying malignancy, sarcoidosis, or other chronic illness. An extensive medical and laboratory evaluation ( ANA, anti-dsDNA, anti-ENA, ANCA, and Cryoglobulin)was negative . | ||||
| © 2001-2009, DermAtlas | Image Name: | Toxic_Epidermal_Necrolysis_3_090617 | File Type: | jpg | |
| Diagnosis: | TOXIC EPIDERMAL NECROLYSIS / STEVENS-JOHNSON SYNDROME | Category: | vesiculobullous eruptions / reactive erythema | ||
| Body Site: | total body / face neck / mouth | Age: | 24 years | ||
| Contributor: | Sugathan Paramoo, MD, FRCP(Glasg) | ||||
| Description: | generalized red hyperpigmented patches, crusts, vesicles, and erosions | ||||
| Comments: | A 24-year-old woman consulted her doctor for fever and body ache of 3 days duraton. She was prescribed Ofloxacin 400 mg twice a day aand Patracetamol. Six days later she developed extensive tenderness of her skin with brownish discoloration involving the entire body and oral mucosa.She also had malaise, head ache and generalized tender skin. After 3 weeks of oral steroids and skin care, she was markedly improved. | ||||
| Related Images: | Toxic_Epidermal_Necrolysis_2_090617 | ||||
| © 2001-2009, DermAtlas | Image Name: | Toxic_Epidermal_Necrolysis_2_090617 | File Type: | jpg | |
| Diagnosis: | TOXIC EPIDERMAL NECROLYSIS / STEVENS-JOHNSON SYNDROME | Category: | vesiculobullous eruptions / reactive erythema | ||
| Body Site: | total body / face neck / mouth | Age: | 24 years | ||
| Contributor: | Sugathan Paramoo, MD, FRCP(Glasg) | ||||
| Description: | generalized red hyperpigmented patches, crusts, vesicles, and erosions | ||||
| Comments: | A 24-year-old woman consulted her doctor for fever and body ache of 3 days duraton. She was prescribed Ofloxacin 400 mg twice a day aand Patracetamol. Six days later she developed extensive tenderness of her skin with brownish discoloration involving the entire body and oral mucosa.She also had malaise, head ache and generalized tender skin. After 3 weeks of oral steroids and skin care, she was markedly improved. | ||||
| Related Images: | Toxic_Epidermal_Necrolysis_3_090617 | ||||
| © 2001-2009, DermAtlas | Image Name: | gianotti_crosti_1_090510 | File Type: | jpg | |
| Diagnosis: | GIANOTTI-CROSTI SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | infections and infestations / reactive erythema | ||
| Body Site: | hand / wrist | Age: | 11 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symmetric scattered acral edematous 2-3 mm red papules | ||||
| Comments: | This healthy 11-year-old boy was evaluated for a minimally itchy diffuse papular eruption which was most dens on the extremities for 2 weeks. He had no systemic symptoms but did complain of diarrhea for 2 days before the eruption blossomed. | ||||
| Related Images: | All related Images gianotti_crosti_3_090510 gianotti_crosti_2_090510 | ||||
| © 2001-2009, DermAtlas | Image Name: | gianotti_crosti_2_090510 | File Type: | jpg | |
| Diagnosis: | GIANOTTI-CROSTI SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | infections and infestations / reactive erythema | ||
| Body Site: | hand / knee leg | Age: | 11 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symmetric scattered acral edematous 2-3 mm red papules | ||||
| Comments: | This healthy 11-year-old boy was evaluated for a minimally itchy diffuse papular eruption which was most dens on the extremities for 2 weeks. He had no systemic symptoms but did complain of diarrhea for 2 days before the eruption blossomed. | ||||
| Related Images: | All related Images gianotti_crosti_3_090510 gianotti_crosti_1_090510 | ||||
| © 2001-2009, DermAtlas | Image Name: | gianotti_crosti_3_090510 | File Type: | jpg | |
| Diagnosis: | GIANOTTI-CROSTI SYNDROME / VIRAL INFECTIONS, EXANTHEM | Category: | infections and infestations / reactive erythema | ||
| Body Site: | arm / wrist elbow | Age: | 11 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symmetric scattered acral edematous 2-3 mm red papules | ||||
| Comments: | This healthy 11-year-old boy was evaluated for a minimally itchy diffuse papular eruption which was most dens on the extremities for 2 weeks. He had no systemic symptoms but did complain of diarrhea for 2 days before the eruption blossomed. | ||||
| Related Images: | All related Images gianotti_crosti_2_090510 gianotti_crosti_1_090510 | ||||
| © 2001-2009, DermAtlas | Image Name: | dermatomyositis_1_090308 | File Type: | jpg | |
| Diagnosis: | DERMATOMYOSITIS / HELIOTROPE | Category: | reactive erythema / collagen vascular disease | ||
| Body Site: | face / eye lid | Age: | 11 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symmetric red minimally scaly and edematous patches with subtle central atrophy and overlying telangiectasias | ||||
| Comments: | This 11-year-old boy was evaluated for red scaly patches and plaques on his eye lids, knees, elbows, and bony prominences of his hands. He complained of fatigue and had dramatic proximal muscle weakness. Magnetic resonance imaging of his legs demonstrated muscle inflammation. | ||||
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