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 © 2001-2009, DermAtlas | Image Name: | Molluscum_1_090617 | File Type: | jpg | |
| Diagnosis: | MOLLUSCUM CONTAGIOSUM / HUMAN IMMUNODEFICIENCY VIRUS INFECTION | Category: | infections and infestations / immunodeficiency related | ||
| Body Site: | face / neck nose / cheek | Age: | 36 years | ||
| Contributor: | Vlada Groysman, MD | ||||
| Description: | multiple clustered pearly skin colored 2-5 mm papules many with a central; scaly dimple | ||||
| Comments: | A 34-year-old man complained of multiple flesh-colored papues on his face and arms. Although not symptomatic he was worried, because they continued to spread. He was recently diagnosed with Human immunodeficiency virus infection and had a CD4 count of 156. | ||||
 © 2001-2009, DermAtlas | Image Name: | Lymphomatoid_Papulosis_HIV_1_080114 | File Type: | jpg | |
| Diagnosis: | LYMPHOMATOID PAPULOSIS | Category: | neoplasm, leukemia/lymphoma / immunodeficiency related | ||
| Body Site: | leg / thigh / thigh | Age: | 53 years | ||
| Contributor: | Azzam Bittar, MD | ||||
| Description: | generalized symmetric red indurated papules, plaques,and nodules with overlying scale, ulceration, crusting and hypo and hyperpigmentation | ||||
| Comments: | A 53-year-old Human Immunodeficiency virus positive man with a CD4 count of 97 on antiretroviral therapy was evaluated for pruritic red plaques on the extremities, trunk, and right ear. A skin biopsy showed a dense nodular infiltrate, of large atypical lymphocytes, smaller lymphocytes, and some eosinophiles and neutrophils consistent with lymphomatois papulosis. Immunohistochemical studies performed to further evaluate the immunophenotype of the lymphocytes showed that the infiltrate was comprised of CD30 T cells with a few CD20, CD8, and CD7 positive cells. | ||||
| Related Images: | Lymphomatoid_Papulosis_HIV_2_080114 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_1_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | foot / total body nail, foot | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation, nail atrophy, scale, yellowing | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_2_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | chest / total body chin / abdomen neck | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_3_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | back / total body | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_4_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | back / total body | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_5_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | hand / total body knee / nail, hand | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation, nail atrophy, scarring, yellowing | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_6_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | hand / total body leg / knee | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with lichenoid scaly plaques, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_7_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_7_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | chest / total body abdomen / shoulder arm | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_8_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
 © 2001-2009, DermAtlas | Image Name: | graft_vs_host_disease_8_071128 | File Type: | jpg | |
| Diagnosis: | POIKILODERMA / GRAFT VERSUS HOST DISEASE, CHRONIC / GRAFT VERSUS HOST DISEASE | Category: | cutaneous sign of systemic disease / atrophy / immunodeficiency related | ||
| Body Site: | shoulder / total body chest / abdomen arm | Age: | 62 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | generalized poikiloderma with scale, atrophy, reticulated blanching erythema, and mottled hyperpigmentation | ||||
| Comments: | This 62-year-old man, who received a bone marrow transplant following chemotherapy for leukemia, developed chronic poikiloderma and lichenoid dermatitis thought to be consistent with chronic graft versus host disease. Interestingly, when lymphocyte markers were checked, there were increased numbers of recipient lymphocytes noted in the inflammatory infiltrate on skin biopsy when the skin disease worsened when the dose of immunosuppressives was reduced. This suggested that the disease was related to host lymphocyte injury of altered host antigens possibly induced by immunosupprressive medications. | ||||
| Related Images: | All related Images graft_vs_host_disease_7_071128 graft_vs_host_disease_6_071128 graft_vs_host_disease_5_071128 graft_vs_host_disease_4_071128 graft_vs_host_disease_3_071128 graft_vs_host_disease_2_071128 graft_vs_host_disease_1_071128 | ||||
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