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 © 2001-2009, DermAtlas | Image Name: | eclipse_nevus_1_090731 | File Type: | jpg | |
| Diagnosis: | NEVUS, PIGMENTED, ECLIPSE / NEVUS, PIGMENTED | Category: | lumps & bumps (plaques, nodules, tumors) / neoplasm, benign / hyperpigmentation | ||
| Body Site: | back | Age: | 17 years | ||
| Contributor: | Sherry Guralnick Cohen, CRNP-F | ||||
| Description: | annular tan papules and plaques with minimally elevated brown borders and elevated light brown centers | ||||
| Comments: | This healthy 17-year-old girl developed multiple eclipse nevi on her back. | ||||
| Related Images: | eclipse_nevus_2_090731 | ||||
 © 2001-2009, DermAtlas | Image Name: | eclipse_nevus_2_090731 | File Type: | jpg | |
| Diagnosis: | NEVUS, PIGMENTED, ECLIPSE / NEVUS, PIGMENTED | Category: | lumps & bumps (plaques, nodules, tumors) / neoplasm, benign / hyperpigmentation | ||
| Body Site: | back | Age: | 17 years | ||
| Contributor: | Sherry Guralnick Cohen, CRNP-F | ||||
| Description: | annular tan papules and plaques with minimally elevated brown borders and elevated light brown centers | ||||
| Comments: | This healthy 17-year-old girl developed multiple eclipse nevi on her back. | ||||
| Related Images: | eclipse_nevus_1_090731 | ||||
 © 2001-2009, DermAtlas | Image Name: | Giant_cell_tumor_2_090617 | File Type: | jpg | |
| Diagnosis: | GIANT CELL TUMOR | Category: | lumps & bumps (plaques, nodules, tumors) / neoplasm, benign / orthopedic disorders | ||
| Body Site: | hand / finger / finger | Age: | 40 years | ||
| Contributor: | Nikolaos Sferopoulos, MD | ||||
| Description: | 1.5 cm yellow rubbery tumor | ||||
| Comments: | A 40-year-old man developed a painless lump 10 months ago on the ventral surface of the middle phalanx of his index finger. The tumor was excised, and biopsy revealed a giant cell tumor of the tendon sheath. | ||||
| Related Images: | Giant_cell_tumor_1_090617 | ||||
 © 2001-2009, DermAtlas | Image Name: | Giant_cell_tumor_1_090617 | File Type: | jpg | |
| Diagnosis: | GIANT CELL TUMOR | Category: | lumps & bumps (plaques, nodules, tumors) / neoplasm, benign / orthopedic disorders | ||
| Body Site: | hand / finger / finger | Age: | 40 years | ||
| Contributor: | Nikolaos Sferopoulos, MD | ||||
| Description: | 1.5 cm subcutaneous tumor | ||||
| Comments: | A 40-year-old man developed a painless lump 10 months ago on the ventral surface of the middle phalanx of his index finger. The tumor was excised, and biopsy revealed a giant cell tumor of the tendon sheath. | ||||
| Related Images: | Giant_cell_tumor_2_090617 | ||||
 © 2001-2009, DermAtlas | Image Name: | Neurofibromatosis_1_090518 | File Type: | jpg | |
| Diagnosis: | NEUROFIBROMATOSIS / CAFé AU LAIT SPOT / NEUROFIBROMA | Category: | neoplasm, benign / genodermatosis/genetic disorder / hyperpigmentation | ||
| Body Site: | chest / abdomen arm | Age: | 27 years | ||
| Contributor: | Ravi Singh | ||||
| Description: | generalized soft compressible skin colored to light brownish-purple papules and nodules | ||||
| Comments: | This 27-year-old man had an increasing number of soft tissue tumors over much of the skin surface. He had a history of hydrocephalus which was persistent despite treatment with folk remedies. | ||||
 © 2001-2009, DermAtlas | Image Name: | vulva_nevus_2_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, GENITAL / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | vulva (labia) | Age: | 10 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | The melanocytic nests are large and expansile. They are located at all positions along the retia. There is the appearance of loss of cellular cohesion within the nests. Individual melanocytes are enlarged. Mitotic activity is not appreciated. | ||||
| Comments: | This 10 year old female presented with a pigmented papule on her vulva. A subset of genital nevi look unremarkable clinically but have atypical histologic features. This is well-described in the literature. Genital nevi include those on the labia, mons, perineum, penis and scrotum. The histologic features may mimic nodular melanoma. Often times, these nevi have large expansile nests, located at all positions along the retia. There is typically loss of cellular cohesion. There may be cytologic atypia, both epidermally and dermally. Rare mitoses may even be observed. Because it is rare for premenapausal women to develop vulvar melanoma, these features should be heavily scrutinized and the lesion excised if in doubt [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | vulva_nevus_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | vulva_nevus_1_090401 | File Type: | jpg | |
| Diagnosis: | NEVUS, GENITAL / NEVUS, PIGMENTED, ATYPICAL | Category: | neoplasm, melanocytic / neoplasm, benign | ||
| Body Site: | vulva (labia) | Age: | 10 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | At low power, the epidermis is acanthotic and papillomatous. Thre is a cellular nevomelanocytic lesion, involving the epidermis and dermis. There is overall symmetry. | ||||
| Comments: | This 10 year old female presented with a pigmented papule on her vulva. A subset of genital nevi look unremarkable clinically but have atypical histologic features. This is well-described in the literature. Genital nevi include those on the labia, mons, perineum, penis and scrotum. The histologic features may mimic nodular melanoma. Often times, these nevi have large expansile nests, located at all positions along the retia. There is typically loss of cellular cohesion. There may be cytologic atypia, both epidermally and dermally. Rare mitoses may even be observed. Because it is rare for premenapausal women to develop vulvar melanoma, these features should be heavily scrutinized and the lesion excised if in doubt [J Cutan Pathol 2008;35:889-898]. | ||||
| Related Images: | vulva_nevus_2_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | trichoblastoma_2_090401 | File Type: | jpg | |
| Diagnosis: | TRICHOBLASTOMA / NEVUS SEBACEUS | Category: | neoplasm, adnexal, follicular / neoplasm, benign | ||
| Body Site: | scalp | Age: | 54 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | At higher power, these basaloid collections form primitive structures, with finger- or floret-like projections into the hypercellular stroma. There are scattered suggestions of papillary mesenchymal bodies, where the stroma sweeps into the basaoild structures. There is no signficant peritumoral clefting, atypia or mitotic activity. The cells are monomorphous and bland. | ||||
| Comments: | This 54 year old woman presented with a solitary plaque on her scalp. Clinically, there was a nevus sebaceus (not seen on the biopsy) with a prominent papule, which was biopsied. Trichoblastomas and other basaloid proliferations are commonly observed in association with nevus sebaceus. Some authors consider trichoblastomas to have low-grade malignant potential like a basal cell carcinoma, but the majority, if not all, are benign with a more hamartomatous quality. This is a typical example of a trichoblastoma, mimicking a BCC at low power. Trichoblastomas tend to have organoid or primitive follicular differentiation with a hypercellular and condensed stroma, and lack of peritumor clefting or significant atypia. Pigmentation is common, as in this case. | ||||
| Related Images: | trichoblastoma_1_090401 | ||||
 © 2001-2009, DermAtlas | Image Name: | angiofibroma_2_090510 | File Type: | jpg | |
| Diagnosis: | ANGIOFIBROMA / TUBEROUS SCLEROSIS | Category: | genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) / neoplasm, benign | ||
| Body Site: | face / cheek nose | Age: | 15 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple symmetric 1-3 mm brown papules | ||||
| Comments: | This healthy adolescent with tuberous sclerosis complained of irritated papules on her face and nose since elementary school and several birthmarks on her forehead, trunk, and extremities. Multiple angiofibromas on her face and small areas in the collagenomas on her forehead, left arm, and chest were treated with the Q-switched alexandrite laser at 14 J/cm2, 10 Hz, and spot size 2 mm. cooling device at level 3. Further treatment was scheduled pending the results of the test spots. | ||||
| Related Images: | All related Images angiofibroma_3_090510 angiofibroma_1_090510 collagenoma_3_090510 collagenoma_2_090510 | ||||
 © 2001-2009, DermAtlas | Image Name: | angiofibroma_1_090510 | File Type: | jpg | |
| Diagnosis: | ANGIOFIBROMA / TUBEROUS SCLEROSIS | Category: | genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) / neoplasm, benign | ||
| Body Site: | face / cheek nose | Age: | 15 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple symmetric 1-3 mm brown papules | ||||
| Comments: | This healthy adolescent with tuberous sclerosis complained of irritated papules on her face and nose since elementary school and several birthmarks on her forehead, trunk, and extremities. Multiple angiofibromas on her face and small areas in the collagenomas on her forehead, left arm, and chest were treated with the Q-switched alexandrite laser at 14 J/cm2, 10 Hz, and spot size 2 mm. cooling device at level 3. Further treatment was scheduled pending the results of the test spots. | ||||
| Related Images: | All related Images angiofibroma_3_090510 angiofibroma_2_090510 collagenoma_3_090510 collagenoma_2_090510 | ||||
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