 | Your DermAtlas query returned 4 ImagesClick on the IMAGE to see an enlargement. |
 © 2001-2009, DermAtlas | Image Name: | Grave_1_030306 | File Type: | jpg | |
| Diagnosis: | ACROPACHY, THYROID / MYXEDEMA, PRETIBIAL / GRAVE DISEASE | Category: | cutaneous sign of systemic disease / Metabolic disorders / thyroid disease associated | ||
| Body Site: | hand | Age: | 67 years | ||
| Contributor: | Rebecca Kazin, MD | ||||
| Description: | acropachy with soft tissue swelling of digits, joint enlargement, and clubbing of fingers | ||||
| Comments: | This 67-year-old man had a history of hypothyroidism for which he received L-thyroxine. Two years later he was diagnosed with ophthalmopathy from Grave disease. He was treated with propylthiouracil and prednisone. He subsequently developed pretibial myxedema and acropachy. | ||||
| Related Images: | Grave_2_030306 | ||||
 © 2001-2009, DermAtlas | Image Name: | myxedema_6_030205 | File Type: | jpg | |
| Diagnosis: | MYXEDEMA, PRETIBIAL / ACROPACHY, THYROID | Category: | cutaneous sign of systemic disease / Metabolic disorders / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | hand | Age: | 52 years | ||
| Contributor: | Michael Viglione, MD | ||||
| Description: | The deep reticular dermis contains mild perivascular lymphocytic infiltrate. Many of the deep dermal collagen fibers are separated from one another. Alcian blue demonstrates increased interstitial mucin within the deep dermis. | ||||
| Comments: | These histologic features are typical of pretibial myxedema. | ||||
 © 2001-2009, DermAtlas | Image Name: | myxedema_5_030205 | File Type: | jpg | |
| Diagnosis: | MYXEDEMA, PRETIBIAL / ACROPACHY, THYROID / GRAVE DISEASE | Category: | lumps & bumps (plaques, nodules, tumors) / Metabolic disorders / cutaneous sign of systemic disease / hyperpigmentation | ||
| Body Site: | hand / finger | Age: | 52 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | dramatic thichening and hyperpigmentation with deep ridges | ||||
| Comments: | This 52-year-old woman with a 5 year history of goiter and Grave disease developed progressive nontender thickening with exuberant folding of the skin on the shins and tops of the feet. She also had nontender subcutaneous nodules on her upper legs, hands, and arms, diffuse thickening of the soft tissue of the hands and fingers and thickening of the soft tissue of the orbits with bilateral proptosis. | ||||
| Related Images: | All related Images myxedema_1_030205 myxedema_2_030205 myxedema_3_030205 myxedema_4_030205 | ||||
 © 2001-2009, DermAtlas | Image Name: | myxedema_3_030205 | File Type: | jpg | |
| Diagnosis: | MYXEDEMA, PRETIBIAL / ACROPACHY, THYROID / GRAVE DISEASE | Category: | lumps & bumps (plaques, nodules, tumors) / Metabolic disorders / cutaneous sign of systemic disease / hyperpigmentation | ||
| Body Site: | hand / finger | Age: | 52 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | thickening of the skin, soft tissues and bone, 5 cm nodule on hand with overlying hyperpigmentation | ||||
| Comments: | This 52-year-old woman with a 5 year history of goiter and Grave disease developed progressive nontender thickening with exuberant folding of the skin on the shins and tops of the feet. She also had nontender subcutaneous nodules on her upper legs, hands, and arms, diffuse thickening of the soft tissue of the hands and fingers and thickening of the soft tissue of the orbits with bilateral proptosis. The nodules showed myxedema, and the diffuse thickening of the hands and feet were consistent with thyroid acropachy. | ||||
| Related Images: | All related Images myxedema_1_030205 myxedema_2_030205 myxedema_4_030205 myxedema_5_030205 | ||||
    Books by the Dermatlas Editors | © DermAtlas, Johns Hopkins University; 2000-2009 |
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