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DermAtlas: HAND - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Rheumatoid_hand_1_080715   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS /
LENTIGO /
LENTIGO, SOLAR
  Category: collagen vascular disease
Body Site: hand / finger   Age: 75 years
Contributor: Nikolaos Sferopoulos, MD    
Description: ulnar deviation of fingers; 0.5-1 cm brown macules
Comments: A 75-year-old woman with rheumatoid arthritis demonstrates unlar deviation of the fingers on the left hand.

DermAtlas: HAND - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Rheumatoid_arthritis_dactylitis_2_071207   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS   Category: collagen vascular disease
Body Site: hand / finger / wrist   Age: 12 years
Contributor: Nikolaos Sferopoulos, MD    
Description: swelling of the right middle finger and thumb
Comments: A 12-year-old girl developed swelling and restriction of motion of the right middle finger 6 months ago and the left wrist a month ago. She was afebrile and laboratory findings were normal with the exception of the antinuclear antibody titer that was positive at 1:80. MRI indicated inflammatory joint fluid in the left wrist and carpometacarpal and metacarpophalangeal joints of the thumb and on the right proximal interphalangeal joint of the middle finger and the interphalangeal joint of the thumb.
Related Images: Rheumatoid_arthritis_dactylitis_1_071207 

DermAtlas: HAND - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Rheumatoid_arthritis_dactylitis_1_071207   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS   Category: collagen vascular disease
Body Site: hand / finger / wrist   Age: 12 years
Contributor: Nikolaos Sferopoulos, MD    
Description: swelling of the left wrist and thumb and right middle finger and thumb
Comments: A 12-year-old girl developed swelling and restriction of motion of the right middle finger 6 months ago and the left wrist a month ago. She was afebrile and laboratory findings were normal with the exception of the antinuclear antibody titer that was positive at 1:80. MRI indicated inflammatory joint fluid in the left wrist and carpometacarpal and metacarpophalangeal joints of the thumb and on the right proximal interphalangeal joint of the middle finger and the interphalangeal joint of the thumb.
Related Images: Rheumatoid_arthritis_dactylitis_2_071207 

DermAtlas: Histology - rheumatoid neutrophilic dermatosis
© 2001-2009, DermAtlas
Image Name: rheumatoid_neut_derm_2_070201   File Type: jpg
Diagnosis: RHEUMATOID NEUTROPHILIC DERMATOSIS /
RHEUMATOID ARTHRITIS
  Category: cutaneous sign of systemic disease /
vesiculobullous eruptions /
histologic finding
Body Site: forearm   Age: 49 years
Contributor: Greg Hosler, MD, PhD    
Description: The infiltrate consists almost exclusively of neutrophils. There is no evidence of vasculitis.
Comments: This is a great example of a rare case of rheumatoid neutrophilic dermatosis. This patient had severe rheumatoid arthritis and developed plaques and bulla over the forearms. Rheumatoid neutrophilic dermatosis is a rare manifestation of severe joint disease, as in this case. Histologically, this is one of the neutrophilic dermatoses along with Sweet syndrome, cellulitis, pyoderma gangrenosum and others. The bulla are often secondary, and not always seen. Distinction between these entities is virtually impossible without clinical history.
Related Images: rheumatoid_neut_derm_1_070201 

DermAtlas: Histology - rheumatoid neutrophilic dermatosis
© 2001-2009, DermAtlas
Image Name: rheumatoid_neut_derm_1_070201   File Type: jpg
Diagnosis: RHEUMATOID NEUTROPHILIC DERMATOSIS /
RHEUMATOID ARTHRITIS
  Category: cutaneous sign of systemic disease /
vesiculobullous eruptions /
histologic finding
Body Site: forearm   Age: 49 years
Contributor: Greg Hosler, MD, PhD    
Description: There is separation of the epidermis from the dermis in a subepidermal plane. The papillary dermis is filled with neutrophils. The infiltrate extends to the mid demis.
Comments: This is a great example of a rare case of rheumatoid neutrophilic dermatosis. This patient had severe rheumatoid arthritis and developed plaques and bulla over the forearms. Rheumatoid neutrophilic dermatosis is a rare manifestation of severe joint disease, as in this case. Histologically, this is one of the neutrophilic dermatoses along with Sweet syndrome, cellulitis, pyoderma gangrenosum and others. The bulla are often secondary, and not always seen. Distinction between these entities is virtually impossible without clinical history.
Related Images: rheumatoid_neut_derm_2_070201 

DermAtlas: NECK - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Juvenile_Rheumatoid_Arthritis_1_060724   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS /
TORTICOLLIS
  Category: collagen vascular disease
Body Site: neck   Age: 3 years
Contributor: Nikolaos Sferopoulos, MD    
Description: torticollis
Comments: A 3-year-old boy rwas evaluated for acquired torticollis and a diffuse swelling of the third right toe. Stiffness and limitation of motion but no tenderness of the cervical spine had been noted approximately 6 months ago. A fusiform, painless swelling was also noted on the left third toe. Magnetic resonance imaging(MRI) of the cervical spine indicated no abnormal findings, while an MRI of the foot was indicative of fibromatosis. A biopsy was performed from the toe that showed mild synovitis of the tendons. Knee joint involvement followed 6 months later. Medical treatment for rheumatoid arthritis was then started and the toe swelling rapidly subsided.
Related Images: Juvenile_Rheumatoid_Arthritis_2_060724 

DermAtlas: TOE - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Juvenile_Rheumatoid_Arthritis_2_060724   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS /
DACTYLITIS, RHEUMATOID
  Category: collagen vascular disease /
orthopedic disorders
Body Site: toe   Age: 3 years
Contributor: Nikolaos Sferopoulos, MD    
Description: asymptomatic swelling
Comments: A 3-year-old boy rwas evaluated for acquired torticollis and a diffuse swelling of the third right toe. Stiffness and limitation of motion but no tenderness of the cervical spine had been noted approximately 6 months ago. A fusiform, painless swelling was also noted on the left third toe. Magnetic resonance imaging(MRI) of the cervical spine indicated no abnormal findings, while an MRI of the foot was indicative of fibromatosis. A biopsy was performed from the toe that showed mild synovitis of the tendons. Knee joint involvement followed 6 months later. Medical treatment for rheumatoid arthritis was then started and the toe swelling rapidly subsided.
Related Images: Juvenile_Rheumatoid_Arthritis_1_060724 

DermAtlas: EYE - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: episcleritis_1_060407   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS   Category: collagen vascular disease
Body Site: eye   Age: 14 years
Contributor: Ajoy Biswas, MD    
Description:
Comments: This adolescent girl demonstrates conjunctival injection associated with episcleritis secondary to juvenile rheumatoid arthritis.

DermAtlas: FINGER - rheumatoid arthritis
© 2001-2009, DermAtlas
Image Name: Juvenile_Rheumatoid_Arthritis_1_050831   File Type: jpg
Diagnosis: RHEUMATOID ARTHRITIS   Category: collagen vascular disease
Body Site: finger   Age: 2 years
Contributor: Nikolaos Sferopoulos, MD    
Description: swelling of the middle finger on the left hand
Comments: A 2-year-old girl was seen for swelling and restriction of motion of the middle finger of the left hand which appeared 4 months ago. The child was afebrile and had no evidence of systemic disease. Radiographs indicated periosteal reaction of the middle phalanx. Magmetic resonance imaging showed tenosynovitis of the flexor tendons as well as thickening of the synovium with inflammatory joint fluid in both the metacarpal-phalangeal and proximal interphalangeal joints. The antinuclear antibody titer was positive at 1:320. Knee joint involvement followed one month later.

DermAtlas: THIGH - Still disease
© 2001-2009, DermAtlas
Image Name: rash_1_031219   File Type: jpg
Diagnosis: STILL DISEASE /
RHEUMATOID ARTHRITIS /
MORBILLIFORM ERUPTION
  Category: reactive erythema
Body Site: thigh / abdomen   Age: 21 years
Contributor: Patti Pickles    
Description: generalized and confluent red papules and plaques
Comments: This 21-year-old woman, who was diagnosed with juvenile rheumatoid arthritis, developed a widespread morbilliform eruption on her trunk and proximal esxtremities associated with fever when her disease flared.

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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