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DermAtlas: Histology - fibrous papule
© 2001-2010, DermAtlas
Image Name: fibrous_papule_2_060327   File Type: jpg
Diagnosis: FIBROUS PAPULE /
ANGIOFIBROMA
  Category: neoplasm, fibrohistiocytic /
neoplasm, benign
Body Site: nose   Age: 29 years
Contributor: Greg Hosler, MD, PhD    
Description: A close up of the lesion shows an unremarkable epidermis. The stroma is fibrotic with scattered stellate fibroblasts. Ectatic vessels are characteristic.
Comments: This lesion was submitted from the nose of a 29-year-old woman. Fibrous papules are common lesions, usually on the nose or cheek. Some authors feel these represent senescent nevi. The histology is of an angiofibroma, with dilated vessels and stellate fibroblasts. The fibrosis often replaces solar elastosis.
Related Images: fibrous_papule_1_060327 

DermAtlas: Histology - fibrous papule
© 2001-2010, DermAtlas
Image Name: fibrous_papule_1_060327   File Type: jpg
Diagnosis: FIBROUS PAPULE /
ANGIOFIBROMA
  Category: neoplasm, fibrohistiocytic /
neoplasm, benign
Body Site: nose   Age: 29 years
Contributor: Greg Hosler, MD, PhD    
Description: Histologic sections of skin show a polypoid lesion with a fibrous core. Solar elastosis is not identified.
Comments: This lesion was submitted from the nose of a 29-year-old woman. Fibrous papules are common lesions, usually on the nose or cheek. Some authors feel these represent senescent nevi. The histology is of an angiofibroma, with dilated vessels and stellate fibroblasts. The fibrosis often replaces solar elastosis.
Related Images: fibrous_papule_2_060327 

DermAtlas: CHEEK - angiofibroma
© 2001-2010, DermAtlas
Image Name: angiofibromas_1_030917   File Type: jpg
Diagnosis: ANGIOFIBROMA /
TUBEROUS SCLEROSIS /
FIBROUS PAPULE
  Category: lumps & bumps (plaques, nodules, tumors) /
genodermatosis/genetic disorder
Body Site: cheek / nose
face
  Age: 13 years
Contributor: Bernard Cohen, MD    
Description: light brown 2-4 mm smooth topped dome shaped papules
Comments: This healthy adolescent was concerned about gradually increasing numbers of fibrotic papules on his cheeks which were mistaken for comedones. A skin biopsy of the largest papule on the side of his nose showed the typical changes of an angiofibroma. There was no family history of tuberous sclerosis. An evaluation for this autosomal dominant genodermatosis was planned.
Related Images: angiofibromas_2_030917 

DermAtlas: CHEEK - angiofibroma
© 2001-2010, DermAtlas
Image Name: angiofibromas_2_030917   File Type: jpg
Diagnosis: ANGIOFIBROMA /
TUBEROUS SCLEROSIS /
FIBROUS PAPULE
  Category: lumps & bumps (plaques, nodules, tumors) /
genodermatosis/genetic disorder
Body Site: cheek / nose
face
  Age: 13 years
Contributor: Bernard Cohen, MD    
Description: light brown 2-4 mm smooth topped dome shaped papules
Comments: This healthy adolescent was concerned about gradually increasing numbers of fibrotic papules on his cheeks which were mistaken for comedones. A skin biopsy of the largest papule on the side of his nose showed the typical changes of an angiofibroma. There was no family history of tuberous sclerosis. An evaluation for this autosomal dominant genodermatosis was planned.
Related Images: angiofibromas_1_030917 

                             
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© DermAtlas, Johns Hopkins University; 2000-2010
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Jan-18-2010
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