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 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_11_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_10_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_9_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_8_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_7_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_6_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. | ||||
| Comments: | These changes are consistent with but not specific of Crohn disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_5_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | cobblestoning of the mucosa with linear ulcers and hyperplastic folds | ||||
| Comments: | This 13-year-old girl was referred for evaluation of oral ulcerations, facial swelling and oral pain. A concomitant history of swelling involving the lower lip, cheeks and cervical lymphadenopathy was also noted. Last year she missed 27 school days due to abdominal pain. She had a tonsillectomy at 2 years of age and complained of severe depression and anxiety, nasal stuffiness, asthma, and abdominal pain. She had multiple treatments including oral antibiotics, parenteral antibiotics, chlorhexidine rinses, and topical steroids. A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. Further evaluation by pediatric gastroenterology including upper and lower gastrointestinal tract studies showed characteristic changes of Crohn disease. Oral and gastrointestinal lesions and symptoms resolved with treatment of her inflammatory bowel disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_4_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | cobblestoning of the mucosa with linear ulcers and hyperplastic folds | ||||
| Comments: | This 13-year-old girl was referred for evaluation of oral ulcerations, facial swelling and oral pain. A concomitant history of swelling involving the lower lip, cheeks and cervical lymphadenopathy was also noted. Last year she missed 27 school days due to abdominal pain. She had a tonsillectomy at 2 years of age and complained of severe depression and anxiety, nasal stuffiness, asthma, and abdominal pain. She had multiple treatments including oral antibiotics, parenteral antibiotics, chlorhexidine rinses, and topical steroids. A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. Further evaluation by pediatric gastroenterology including upper and lower gastrointestinal tract studies showed characteristic changes of Crohn disease. Oral and gastrointestinal lesions and symptoms resolved with treatment of her inflammatory bowel disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_3_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | buccal mucosa / mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | cobblestoning of the mucosa with linear ulcers and hyperplastic folds | ||||
| Comments: | This 13-year-old girl was referred for evaluation of oral ulcerations, facial swelling and oral pain. A concomitant history of swelling involving the lower lip, cheeks and cervical lymphadenopathy was also noted. Last year she missed 27 school days due to abdominal pain. She had a tonsillectomy at 2 years of age and complained of severe depression and anxiety, nasal stuffiness, asthma, and abdominal pain. She had multiple treatments including oral antibiotics, parenteral antibiotics, chlorhexidine rinses, and topical steroids. A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. Further evaluation by pediatric gastroenterology including upper and lower gastrointestinal tract studies showed characteristic changes of Crohn disease. Oral and gastrointestinal lesions and symptoms resolved with treatment of her inflammatory bowel disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_2_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
 © 2001-2010, DermAtlas | Image Name: | Inflammatory_bowel_disease_2_090421 | File Type: | jpg | |
| Diagnosis: | CROHN DISEASE / PERLECHE / GRANULOMATOUS REACTION / CHEILITIS | Category: | granulomatous disorder / cutaneous sign of systemic disease / dental/oral disorder / gastrointestinal disorder | ||
| Body Site: | vermillion/ vermilion border / lip mouth | Age: | 13 years | ||
| Contributor: | James Scuibba | ||||
| Description: | symmetric erythema, cracking, fissuring, crusting, and erosions | ||||
| Comments: | This 13-year-old girl was referred for evaluation of oral ulcerations, facial swelling and oral pain. A concomitant history of swelling involving the lower lip, cheeks and cervical lymphadenopathy was also noted. Last year she missed 27 school days due to abdominal pain. She had a tonsillectomy at 2 years of age and complained of severe depression and anxiety, nasal stuffiness, asthma, and abdominal pain. She had multiple treatments including oral antibiotics, parenteral antibiotics, chlorhexidine rinses, and topical steroids. A biopsy of the buccal mucosa revealed focal and diffuse chronic inflammation with scattered non-caseating epitheloid granulomas. Special stains were negative for acid fast bacteria, fungus, and polarizing microscopy was negative for foreign material. Further evaluation by pediatric gastroenterology including upper and lower gastrointestinal tract studies showed characteristic changes of Crohn disease. Oral and gastrointestinal lesions and symptoms resolved with treatment of her inflammatory bowel disease. | ||||
| Related Images: | All related Images Inflammatory_bowel_disease_1_090421 Inflammatory_bowel_disease_3_090421 Inflammatory_bowel_disease_4_090421 Inflammatory_bowel_disease_5_090421 Inflammatory_bowel_disease_6_090421 Inflammatory_bowel_disease_7_090421 Inflammatory_bowel_disease_8_090421 Inflammatory_bowel_disease_9_090421 Inflammatory_bowel_disease_10_090421 Inflammatory_bowel_disease_11_090421 | ||||
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    Books by the Dermatlas Editors |  ACI Journal | © DermAtlas, Johns Hopkins University; 2000-2010 |
Link directly to this page: http://DermAtlas.med.jhmi.edu/derm/result.cfm?Diagnosis=-1736522750