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 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_5_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / chest / abdomen | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_6_080906 dermatisis_herpetiformis_1_080906 dermatisis_herpetiformis_2_080906 dermatisis_herpetiformis_3_080906 dermatisis_herpetiformis_4_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_4_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / wrist | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_6_080906 dermatisis_herpetiformis_1_080906 dermatisis_herpetiformis_2_080906 dermatisis_herpetiformis_3_080906 dermatisis_herpetiformis_5_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_3_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / forearm wrist | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_6_080906 dermatisis_herpetiformis_1_080906 dermatisis_herpetiformis_2_080906 dermatisis_herpetiformis_4_080906 dermatisis_herpetiformis_5_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_2_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm hip / abdomen | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_6_080906 dermatisis_herpetiformis_1_080906 dermatisis_herpetiformis_3_080906 dermatisis_herpetiformis_4_080906 dermatisis_herpetiformis_5_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_1_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / buttock hip / abdomen | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_6_080906 dermatisis_herpetiformis_2_080906 dermatisis_herpetiformis_3_080906 dermatisis_herpetiformis_4_080906 dermatisis_herpetiformis_5_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatisis_herpetiformis_6_080906 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions / vesiculobullous eruptions, immunobullous | ||
| Body Site: | arm / abdomen | Age: | 24 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | widely disseminated but primarily acral 2-4 mm vesicles with excoriations and crusts | ||||
| Comments: | This heatlhy 24-year-old man developed an itchy vesicular eruption on the extensor surfaces of his arms and legs and buttocks, hips, and lower abdomen a year ago. Skin biopsy demonstrated a subepidermal inflammatory vesicles concentrated at the dermal papillae with neutrophils. Immunofluorescence showed granular IgA at the epidermal-dermal junction. | ||||
| Related Images: | All related Images dermatisis_herpetiformis_1_080906 dermatisis_herpetiformis_2_080906 dermatisis_herpetiformis_3_080906 dermatisis_herpetiformis_4_080906 dermatisis_herpetiformis_5_080906 | ||||
 © 2001-2009, DermAtlas | Image Name: | henna_tattoo_1_080903 | File Type: | jpg | |
| Diagnosis: | DERMATITIS, CONTACT ALLERGIC / DERMATITIS HERPETIFORMIS / TATTOO COMPLICATION / TATTOO | Category: | annular eruption / hypersensitivity | ||
| Body Site: | arm | Age: | 10 years | ||
| Contributor: | Tim Doran, MD | ||||
| Description: | red scaly olympic plaques | ||||
| Comments: | This 10-year-old boy developed a delayed hypersensitivity reaction to the paraphenylenediamine pigment enhancer in a henna tattoo dedicated to the olympics 3 weeks after placement of the tattoo. | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatitis_herpetiformis_1_080801 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions | ||
| Body Site: | hip / elbow | Age: | 70 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | There is a moderate inflammatory infiltrate, involving the dermal papillae and extending to the mid-reticular dermis. At one edge of the biopsy, there is a subepidermal cleft. | ||||
| Comments: | This 70 year old man presented with pruritic grouped vesicles on his extensor surfaces. This is a characteristic presentation with great pathology. The histology in this case is classic, with aggregates of neutrophils in the dermal papillae. The immunofluoresence was performed and confirmed the presence of IgA deposition in these papillae, but the diagnosis could be made on H&E. The differential diagnosis includes linear IgA disease, but the prominent dermal papillary aggegates would be unusual for that entity. | ||||
| Related Images: | All related Images dermatitis_herpetiformis_3_080801 dermatitis_herpetiformis_2_080801 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatitis_herpetiformis_2_080801 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions | ||
| Body Site: | hip / elbow | Age: | 70 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | At higher power, there is a classic display of neutrophilic aggregates in the dermal papillae. Neutrophils also align along the junction. Scattered eosinophils are also noted. | ||||
| Comments: | This 70 year old man presented with pruritic grouped vesicles on his extensor surfaces. This is a characteristic presentation with great pathology. The histology in this case is classic, with aggregates of neutrophils in the dermal papillae. The immunofluoresence was performed and confirmed the presence of IgA deposition in these papillae, but the diagnosis could be made on H&E. The differential diagnosis includes linear IgA disease, but the prominent dermal papillary aggegates would be unusual for that entity. | ||||
| Related Images: | All related Images dermatitis_herpetiformis_3_080801 dermatitis_herpetiformis_1_080801 | ||||
 © 2001-2009, DermAtlas | Image Name: | dermatitis_herpetiformis_3_080801 | File Type: | jpg | |
| Diagnosis: | DERMATITIS HERPETIFORMIS | Category: | vesiculobullous eruptions | ||
| Body Site: | hip / elbow | Age: | 70 years | ||
| Contributor: | Greg Hosler, MD, PhD | ||||
| Description: | Immunofluoresence highlights the dermal papillae using antibodies to IgA. Deposition along the basement membrane zone may occur but is not a prominent feature here. | ||||
| Comments: | This 70 year old man presented with pruritic grouped vesicles on his extensor surfaces. This is a characteristic presentation with great pathology. The histology in this case is classic, with aggregates of neutrophils in the dermal papillae. The immunofluoresence was performed and confirmed the presence of IgA deposition in these papillae, but the diagnosis could be made on H&E. The differential diagnosis includes linear IgA disease, but the prominent dermal papillary aggegates would be unusual for that entity. | ||||
| Related Images: | All related Images dermatitis_herpetiformis_2_080801 dermatitis_herpetiformis_1_080801 | ||||
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