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DermAtlas: ARM - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_1_080212   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: lumps & bumps (plaques, nodules, tumors)
Body Site: arm   Age: 15 years
Contributor: Katherine Puttgen, MD    
Description: firm brown to violaceous nodule
Comments: This healthy adolescent girl complained of a few year history of this stable nodule which was intermittently itchy and uncomfortable, and which she requested to have removed.

DermAtlas: THIGH - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_1_070110   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: neoplasm, benign /
hyperpigmentation
Body Site: thigh   Age: 52 years
Contributor: Eric Ehrsam, MD    
Description: flat topped 6 mm well demarcated brown papule with light brown-pink center
Comments: A 52-year-old man developed a pigmented papule of his right thigh. Dermoscopy (x20) revealed a central white patch surrounded by a brown pigment network typical of a dermatofibroma. The lesion was removed and pathology confirmed the diagnosis.
Related Images: dermatofibroma_2_070110 

DermAtlas: Histology - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_2_070110   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: neoplasm, benign /
hyperpigmentation
Body Site: thigh   Age: 52 years
Contributor: Eric Ehrsam, MD    
Description: Dermoscopy (x20) reveals a central white patch surrounded by a brown pigment network typical of a dermatofibroma.
Comments: A 52-year-old man developed a pigmented papule of his right thigh. The lesion was removed and pathology confirmed the diagnosis.
Related Images: dermatofibroma_1_070110 

DermAtlas: Histology - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_aneurysmal_2_060801   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: neoplasm, fibrohistiocytic /
neoplasm, benign
Body Site: forearm   Age: 49 years
Contributor: Greg Hosler, MD, PhD    
Description: The edge of the lesion shows more traditional collagen trapping by short spindled cells. Multinucleated giant cells with abundant pigment are scattered throughout the lesion.
Comments: This is an unusual variant of dermatofibroma, a benign fibrohistiocytic tumor. One can call it a hemosiderotic dermatofibroma or an aneurysmal dermatofibroma, depending on the relative contribution of the vascular component. The presence of pigment may scare the untrained eye, but this pigment is hemosiderin. The differential diagnosis would include a melanocytic or vascular lesion. One must look to the periphery of the lesion to find the more traditional patten of a dermatofibroma.
Related Images: dermatofibroma_aneurysmal_1_060801 

DermAtlas: Histology - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_aneurysmal_1_060801   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: neoplasm, fibrohistiocytic /
neoplasm, benign
Body Site: forearm   Age: 49 years
Contributor: Greg Hosler, MD, PhD    
Description: There is a fibrohistiocytic proliferation within the dermis. The overlying epidermis is mildly thinned with overlying scale. Within the proliferation, there are large cavernous blood-filled spaces. At the periphery of the lesion, the spindle cells trap collagen bundles.
Comments: This is an unusual variant of dermatofibroma, a benign fibrohistiocytic tumor. One can call it a hemosiderotic dermatofibroma or an aneurysmal dermatofibroma, depending on the relative contribution of the vascular component. The presence of pigment may scare the untrained eye, but this pigment is hemosiderin. The differential diagnosis would include a melanocytic or vascular lesion. One must look to the periphery of the lesion to find the more traditional patten of a dermatofibroma.
Related Images: dermatofibroma_aneurysmal_2_060801 

DermAtlas: CALF - dermatofibroma
© 2001-2009, DermAtlas
Image Name: cellular_dermatofibroma_1_040730   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: neoplasm, benign
Body Site: calf / leg   Age: 50 years
Contributor: Susan M Rabizadeh, MD    
Description: 3 X 2 cm firm rubbery smooth topped pink-brown nodule with overlying scale
Comments: A healthy 50-year-old woman was evaluated for a slowly growing protuberant nodule on her left calf for 10-15 years. An excisional biopsy showed a cellular dermatofibroma.

DermAtlas: THIGH - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_2_040612   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: lumps & bumps (plaques, nodules, tumors) /
hyperpigmentation
Body Site: thigh   Age: 13 years
Contributor: Bernard Cohen, MD    
Description: infiltrated 1 cm hyperpigmented nodule
Comments: This healthy adolescent had an itchy brown nodule on the posterior aspect of her left thigh. Histologic changes were typical of a dermatofibroma.
Related Images: dermatofibroma_1_040612 

DermAtlas: THIGH - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_1_040612   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: lumps & bumps (plaques, nodules, tumors) /
hyperpigmentation /
neoplasm, benign
Body Site: thigh   Age: 13 years
Contributor: Bernard Cohen, MD    
Description: infiltrated 1 cm hyperpigmented nodule
Comments: This healthy adolescent had an itchy brown nodule on the posterior aspect of her left thigh. Histologic changes were typical of a dermatofibroma.
Related Images: dermatofibroma_2_040612 

DermAtlas: HIP - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_1_040301   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: lumps & bumps (plaques, nodules, tumors) /
hyperpigmentation
Body Site: hip   Age: 19 years
Contributor: Bernard Cohen, MD    
Description: 1 cm dark browm nodule with well defined borders and grayish scaly center
Comments: This asymptomatic nodule appeared 4 years earlier on the upper thigh of a healthy 19-year-old boy.

DermAtlas: HIP - dermatofibroma
© 2001-2009, DermAtlas
Image Name: dermatofibroma_1_010828   File Type: jpg
Diagnosis: DERMATOFIBROMA   Category: lumps & bumps (plaques, nodules, tumors)
Body Site: hip   Age: 28 years
Contributor: Bernard Cohen, MD    
Description: 1 cm firm pale brown nodule
Comments: An asympromatic firm nodule had been present for 2 years on the hip of a healthy 28 year old woman.

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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