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DermAtlas: GENITAL - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_1_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Adrianna Jackson    
Description: firm rubbern non-pitting edema with surrounding red papules and pustules
Comments: This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
Related Images: All related Images  crohn_disease_6_090905  crohn_disease_5_090905  crohn_disease_4_090905  crohn_disease_3_090905  crohn_disease_2_090905 

DermAtlas: GENITAL - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_2_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Adrianna Jackson    
Description: firm rubbern non-pitting edema with surrounding red papules and pustules
Comments: This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
Related Images: All related Images  crohn_disease_6_090905  crohn_disease_5_090905  crohn_disease_4_090905  crohn_disease_3_090905  crohn_disease_1_090905 

DermAtlas: GENITAL - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_3_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Adrianna Jackson    
Description: firm rubbern non-pitting edema with surrounding red papules and pustules
Comments: This 5-year-old boy had a history of progressive swelling of the scrotum and penis for 6 months. He was growing and developing normally. Although the involved area was only moderately tender, he was extremely uncomfortable as the swelling increased and had difficulty walking. He also had chronic constipation with overflow diarrhea intermittently.
Related Images: All related Images  crohn_disease_6_090905  crohn_disease_5_090905  crohn_disease_4_090905  crohn_disease_2_090905  crohn_disease_1_090905 

DermAtlas: Histology - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_4_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Jakki Junkins-Hopkins    
Description: fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis.
Comments: The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative.
Related Images: All related Images  crohn_disease_6_090905  crohn_disease_5_090905  crohn_disease_3_090905  crohn_disease_2_090905  crohn_disease_1_090905 

DermAtlas: Histology - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_5_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Jakki Junkins-Hopkins    
Description: fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis.
Comments: The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative.
Related Images: All related Images  crohn_disease_6_090905  crohn_disease_4_090905  crohn_disease_3_090905  crohn_disease_2_090905  crohn_disease_1_090905 

DermAtlas: Histology - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_6_090905   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: granulomatous disorder /
gastrointestinal disorder /
cutaneous sign of systemic disease
Body Site: genital / scrotum
penis / perineum
diaper area / groin
  Age: 5 years
Contributor: Jakki Junkins-Hopkins    
Description: fThe specimen shows loose aggregates o fepithelioid histiocytes and multinucleated giant cells within the dermis and subcutaneous tissue. These are also noted amidst the skeletal muscle bundles towards the base of of the biopsy. There is an associated lymphocytic infiltrate within the dermis and epidermis. The epidermis shows exocytosis of lymphocytes and spongiosis.
Comments: The clinical-pathologic featuers favor cutaneous Crohns disease. Stains for fungi, acid fast bacilli, and spirochetes were negative.
Related Images: All related Images  crohn_disease_5_090905  crohn_disease_4_090905  crohn_disease_3_090905  crohn_disease_2_090905  crohn_disease_1_090905 

DermAtlas: DIAPER AREA - inflammatory bowel disease
© 2001-2010, DermAtlas
Image Name: inflammatory_bowel_disease_1_060902   File Type: jpg
Diagnosis: INFLAMMATORY BOWEL DISEASE /
CROHN DISEASE
  Category: granulomatous disorder /
lumps & bumps (plaques, nodules, tumors)
Body Site: diaper area / vulva (labia)
perineum / buttock
anus
  Age: 2 years
Contributor: Bernard Cohen, MD    
Description: 4 X 6 cm red rubbery indurated tumor on the right labia, indurated red plaque over the perineum, and red 1 X 4 cm nodule protruding from the anus
Comments: This healthy toddler had a labial tumor, indurated confluent plaque in the perineum extending onto the medial aspect of the buttocks and perianal skin and tags protruding from the anus for at least 6 months. She was growing well and had normal stools. Endoscopy revealed distal colonic Crohn disease.

DermAtlas: GROIN - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_3_060624   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: cutaneous sign of systemic disease /
granulomatous disorder
Body Site: groin / thigh   Age: 16 years
Contributor: Bernard Cohen, MD    
Description: symmetric friable hemorrhagic reddish purple linear plaques with central erosion and crusting
Comments: This adolescent boy with well controlled inflammatory bowel disease developed chronic weeping burning linear plaques along the groin creases. A biopsy of some of the friable tissue demonstrated chronic inflammation with granulomas.
Related Images: All related Images  crohn_disease_1_060624  crohn_disease_2_060624 

DermAtlas: GROIN - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_2_060624   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: cutaneous sign of systemic disease /
granulomatous disorder
Body Site: groin / thigh   Age: 16 years
Contributor: Bernard Cohen, MD    
Description: symmetric friable hemorrhagic reddish purple linear plaques with central erosion and crusting
Comments: This adolescent boy with well controlled inflammatory bowel disease developed chronic weeping burning linear plaques along the groin creases. A biopsy of some of the friable tissue demonstrated chronic inflammation with granulomas.
Related Images: All related Images  crohn_disease_1_060624  crohn_disease_3_060624 

DermAtlas: GROIN - Crohn disease
© 2001-2010, DermAtlas
Image Name: crohn_disease_1_060624   File Type: jpg
Diagnosis: CROHN DISEASE /
INFLAMMATORY BOWEL DISEASE
  Category: cutaneous sign of systemic disease /
granulomatous disorder
Body Site: groin / thigh   Age: 16 years
Contributor: Bernard Cohen, MD    
Description: symmetric friable hemorrhagic reddish purple linear plaques with central erosion and crusting
Comments: This adolescent boy with well controlled inflammatory bowel disease developed chronic weeping burning linear plaques along the groin creases. A biopsy of some of the friable tissue demonstrated chronic inflammation with granulomas.
Related Images: All related Images  crohn_disease_2_060624  crohn_disease_3_060624 

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© DermAtlas, Johns Hopkins University; 2000-2010
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Jan-18-2010
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