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 © 2001-2010, DermAtlas | Image Name: | lentigines_1_050211 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LENTIGO / NEVUS, PIGMENTED, JUNCTIONAL | Category: | genodermatosis/genetic disorder / hyperpigmentation / congenital malformation | ||
| Body Site: | total body / face neck | Age: | 10 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple disseminated 1-3 mm dark brown macules and papules | ||||
| Comments: | At birth this 10-year-old boy was noted to have generalized brown macules associated with complex congenital malformations including anomalie of the gastrointestinal tract and central nervous system. The pigmented lesions gradually increased in number and many developed an elevated center. A biopsy of a macule showed a lentigo, while a papule showed the features of a junctional nevus. Although he did not satisfy criteria for diagnosis of multiple lentigines syndrome, the cutaneous lesions are undoubtedly a marker for a congenital malformation syndrome. | ||||
| Related Images: | All related Images lentigines_5_050211 lentigines_4_050211 lentigines_3_050211 lentigines_2_050211 | ||||
 © 2001-2010, DermAtlas | Image Name: | lentigines_2_050211 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LENTIGO / NEVUS, PIGMENTED, JUNCTIONAL | Category: | genodermatosis/genetic disorder / hyperpigmentation / congenital malformation | ||
| Body Site: | total body / abdomen arm | Age: | 10 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple disseminated 1-3 mm dark brown macules and papules | ||||
| Comments: | At birth this 10-year-old boy was noted to have generalized brown macules associated with complex congenital malformations including anomalie of the gastrointestinal tract and central nervous system. The pigmented lesions gradually increased in number and many developed an elevated center. A biopsy of a macule showed a lentigo, while a papule showed the features of a junctional nevus. Although he did not satisfy criteria for diagnosis of multiple lentigines syndrome, the cutaneous lesions are undoubtedly a marker for a congenital malformation syndrome. | ||||
| Related Images: | All related Images lentigines_5_050211 lentigines_4_050211 lentigines_3_050211 lentigines_1_050211 | ||||
 © 2001-2010, DermAtlas | Image Name: | lentigines_3_050211 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LENTIGO / NEVUS, PIGMENTED, JUNCTIONAL | Category: | genodermatosis/genetic disorder / hyperpigmentation / congenital malformation | ||
| Body Site: | total body / back | Age: | 10 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple disseminated 1-3 mm dark brown macules and papules | ||||
| Comments: | At birth this 10-year-old boy was noted to have generalized brown macules associated with complex congenital malformations including anomalie of the gastrointestinal tract and central nervous system. The pigmented lesions gradually increased in number and many developed an elevated center. A biopsy of a macule showed a lentigo, while a papule showed the features of a junctional nevus. Although he did not satisfy criteria for diagnosis of multiple lentigines syndrome, the cutaneous lesions are undoubtedly a marker for a congenital malformation syndrome. | ||||
| Related Images: | All related Images lentigines_5_050211 lentigines_4_050211 lentigines_2_050211 lentigines_1_050211 | ||||
 © 2001-2010, DermAtlas | Image Name: | lentigines_4_050211 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LENTIGO / NEVUS, PIGMENTED, JUNCTIONAL | Category: | genodermatosis/genetic disorder / hyperpigmentation / congenital malformation | ||
| Body Site: | total body / back | Age: | 10 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple disseminated 1-3 mm dark brown macules and papules | ||||
| Comments: | At birth this 10-year-old boy was noted to have generalized brown macules associated with complex congenital malformations including anomalie of the gastrointestinal tract and central nervous system. The pigmented lesions gradually increased in number and many developed an elevated center. A biopsy of a macule showed a lentigo, while a papule showed the features of a junctional nevus. Although he did not satisfy criteria for diagnosis of multiple lentigines syndrome, the cutaneous lesions are undoubtedly a marker for a congenital malformation syndrome. | ||||
| Related Images: | All related Images lentigines_5_050211 lentigines_3_050211 lentigines_2_050211 lentigines_1_050211 | ||||
 © 2001-2010, DermAtlas | Image Name: | lentigines_5_050211 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LENTIGO / NEVUS, PIGMENTED, JUNCTIONAL | Category: | genodermatosis/genetic disorder / hyperpigmentation / congenital malformation | ||
| Body Site: | total body / palm hand | Age: | 10 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | multiple disseminated 1-3 mm dark brown macules and papules | ||||
| Comments: | At birth this 10-year-old boy was noted to have generalized brown macules associated with complex congenital malformations including anomalie of the gastrointestinal tract and central nervous system. The pigmented lesions gradually increased in number and many developed an elevated center. A biopsy of a macule showed a lentigo, while a papule showed the features of a junctional nevus. Although he did not satisfy criteria for diagnosis of multiple lentigines syndrome, the cutaneous lesions are undoubtedly a marker for a congenital malformation syndrome. | ||||
| Related Images: | All related Images lentigines_4_050211 lentigines_3_050211 lentigines_2_050211 lentigines_1_050211 | ||||
 © 2001-2010, DermAtlas | Image Name: | leopardsyndrome_1_010907 | File Type: | jpg | |
| Diagnosis: | LEOPARD SYNDROME / MULTIPLE LENTIGINES SYNDROME / LENTIGO | Category: | genodermatosis/genetic disorder / hyperpigmentation | ||
| Body Site: | chest / trunk | Age: | 12 years | ||
| Contributor: | Kerry Bron, MD | ||||
| Description: | multiple disseminated hyperpigmented 2-5 mm macules | ||||
| Comments: | This 12 year old boy with multiple lentigines also had pulmonic stenosis, developmental delay, and undescended testicles, findings associated with L(entigines), E(KG abnormalities), O(cular hypertelorism), P(ulmonic stenosis), A(bmormal genitalia, R(etardation of growth), D(eafness, neurosensory) syndrome. His sister and father had similar skin findings consistent with autosomal dominant inheritance. | ||||
 © 2001-2010, DermAtlas | Image Name: | leopard_1_010205 | File Type: | jpg | |
| Diagnosis: | MULTIPLE LENTIGINES SYNDROME / LEOPARD SYNDROME / LENTIGO | Category: | genodermatosis/genetic disorder / hyperpigmentation | ||
| Body Site: | face / total body | Age: | 14 years | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | diffuse hyperpigmented 2-4 mm macules | ||||
| Comments: | This adolescent with LEOPARD syndrome was referred from pediatric cardiology for dermatology evaluation. He had undescended testicles, pulmonic stenosis, mild retardation, neurosensory hearing loss multiple lentigines. | ||||
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