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Dermatology Images

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DermAtlas: THUMB - abscess
© 2001-2009, DermAtlas
Image Name: pulp_spac_ infection_1_070413   File Type: jpg
Diagnosis: ABSCESS /
STAPHYLOCOCCAL INFECTION
  Category: orthopedic disorders /
infections and infestations
Body Site: thumb / finger   Age: 53 years
Contributor: Nikolaos Sferopoulos, MD    
Description: swelling and erythema of the tip of the thumb
Comments: A pulp space infection of the thumb in a 53-year-old man was characterized by intense pain, erythema and swelling of the palmar tip that required surgical drainage.

DermAtlas: SHOULDER - abscess
© 2001-2009, DermAtlas
Image Name: abscess_1_070413   File Type: jpg
Diagnosis: ABSCESS   Category: orthopedic disorders /
infections and infestations
Body Site: shoulder   Age: 22 years
Contributor: Nikolaos Sferopoulos, MD    
Description: fullness or the right shoulder
Comments: An abscess of the shoulder of a 22-year-old drug addict required surgical drainage.

DermAtlas: THIGH - Staphylococcal infection
© 2001-2009, DermAtlas
Image Name: Staph_Infection_1_060529   File Type: jpg
Diagnosis: STAPHYLOCOCCAL INFECTION /
ABSCESS
  Category: infections and infestations /
reactive erythema
Body Site: thigh   Age: 36 years
Contributor: Troy Lawson    
Description: ulcerated draining abscess with surrounding area of erythema
Comments: This healthy 36-year-old runner developed an abscess on the right inner thigh following infection of an irritated patch from running. He was started on cephalexin and had the area incised after 3 and 5 days of antibiotic theraopy.

DermAtlas: TRUNK - tuberculosis
© 2001-2009, DermAtlas
Image Name: Tuberculous_spondylitis_2_060126   File Type: jpg
Diagnosis: TUBERCULOSIS /
MYCOBACTERIUM INFECTION, TUBERCULOSIS /
SPONDYLITIS /
ABSCESS
  Category: orthopedic disorders /
infections and infestations
Body Site: trunk / back   Age: 36 years
Contributor: Nikolaos Sferopoulos, MD    
Description: A fluctuant cold abscess gravitated and was palpated in the right lumbar region.
Comments: A 36-year-old man with a fever, generalized malaise and loss of weight. There was a history of tuberculous spondylitis for almost a year but he refused to receive any antituberculous drug therapy. Paraspinal abscesses in the thoracic region of the spine were delineated by magnetic resonance imaging.
Related Images: Tuberculous_spondylitis_1_060126 

DermAtlas: TRUNK - tuberculosis
© 2001-2009, DermAtlas
Image Name: Tuberculous_spondylitis_1_060126   File Type: jpg
Diagnosis: TUBERCULOSIS /
MYCOBACTERIUM INFECTION, TUBERCULOSIS /
SPONDYLITIS /
ABSCESS
  Category: orthopedic disorders /
infections and infestations
Body Site: trunk / back   Age: 36 years
Contributor: Nikolaos Sferopoulos, MD    
Description: A fluctuant cold abscess gravitated and was palpated in the right lumbar region.
Comments: A 36-year-old man with a fever, generalized malaise and loss of weight. There was a history of tuberculous spondylitis for almost a year but he refused to receive any antituberculous drug therapy. Paraspinal abscesses in the thoracic region of the spine were delineated by magnetic resonance imaging.
Related Images: Tuberculous_spondylitis_2_060126 

DermAtlas: KNEE - Staphylococcal infection
© 2001-2009, DermAtlas
Image Name: knee_staph_infection_1_060222   File Type: jpg
Diagnosis: STAPHYLOCOCCAL INFECTION /
ABSCESS
  Category: infections and infestations
Body Site: knee   Age: 41 years
Contributor: David Greenspan    
Description: bloody fluctuent 2 cm nodule with surrounding erythema draining pus
Comments: This healthy 41-year-old man who worked as a kayaking day tour guide in Australia developed a painful abscess on his right knee. The infection improved quickly after incision and debridement.

DermAtlas: FOREARM - fungal infection, deep
© 2001-2009, DermAtlas
Image Name: zygomycosis_7_060206   File Type: jpg
Diagnosis: FUNGAL INFECTION, DEEP /
ABSCESS /
ZYGOMYCOSIS
  Category: infections and infestations
Body Site: forearm   Age: 47 years
Contributors: Susan M Rabizadeh, MD
Greg Hosler, MD, PhD
   
Description: 4 X 8 cm well demarcated necrotic black eschar
Comments: This 47-year-old man developed a necrotic ulcer with eschar and purpuric borders following immunosuppression for an orthotopic liver transplant for liver failure from Hepatitis C Virus infection. The lesion was biopsied and sent for both histology and cultures. The clinical differential diagnosis included deep fungal infection and ecthyma gangrenosum. The histopathology showed scattered filamentous fungi within the areas of necrosis. The apparent aseptate and ribbon-like nature of the fungus is highly suggestive of zygomycosis (mucor, rhizopus, etc), however, degenerated Aspergillus species can look like this, and thus cultures are necessary for confirmation.
Related Images: All related Images  zygomycosis_1_060206  zygomycosis_2_060206  zygomycosis_3_060206  zygomycosis_4_060206  zygomycosis_5_060206  zygomycosis_6_060206 

DermAtlas: FOREARM - zygomycosis
© 2001-2009, DermAtlas
Image Name: zygomycosis_6_060206   File Type: jpg
Diagnosis: ZYGOMYCOSIS /
FUNGAL INFECTION, DEEP /
ABSCESS
  Category: infections and infestations
Body Site: forearm   Age: 47 years
Contributors: Susan M Rabizadeh, MD
Greg Hosler, MD, PhD
   
Description: 4 X 8 cm well demarcated necrotic black eschar
Comments: This 47-year-old man developed a necrotic ulcer with eschar and purpuric borders following immunosuppression for an orthotopic liver transplant for liver failure from Hepatitis C Virus infection. The lesion was biopsied and sent for both histology and cultures. The clinical differential diagnosis included deep fungal infection and ecthyma gangrenosum. The histopathology showed scattered filamentous fungi within the areas of necrosis. The apparent aseptate and ribbon-like nature of the fungus is highly suggestive of zygomycosis (mucor, rhizopus, etc), however, degenerated Aspergillus species can look like this, and thus cultures are necessary for confirmation.
Related Images: All related Images  zygomycosis_1_060206  zygomycosis_2_060206  zygomycosis_3_060206  zygomycosis_4_060206  zygomycosis_5_060206  zygomycosis_7_060206 

DermAtlas: Histology - zygomycosis
© 2001-2009, DermAtlas
Image Name: zygomycosis_5_060206   File Type: jpg
Diagnosis: ZYGOMYCOSIS /
FUNGAL INFECTION, DEEP /
ABSCESS
  Category: infections and infestations
Body Site: forearm   Age: 47 years
Contributors: Greg Hosler, MD, PhD
Susan M Rabizadeh, MD
   
Description: This stunning image is from a calcofluor white preparation in this same patient. It is a fluorescence-based stain which brilliantly highlights fungal forms without sifting through artifact, an often frustrating exercise using a standard KOH prep. The wide-angle branching of ribbon-like hyphae mirrors the morphology seen on H&E sections and is characteristic of the zygomycoses, such as Mucor and Rhizopus species.
Comments: This 47-year-old man developed a necrotic ulcer with eschar and purpuric borders following immunosuppression for an orthotopic liver transplant for liver failure from Hepatitis C Virus infection. The lesion was biopsied and sent for both histology and cultures. The clinical differential diagnosis included deep fungal infection and ecthyma gangrenosum. The histopathology showed scattered filamentous fungi within the areas of necrosis. The apparent aseptate and ribbon-like nature of the fungus is highly suggestive of zygomycosis (mucor, rhizopus, etc), however, degenerated Aspergillus species can look like this, and thus cultures are necessary for confirmation.
Related Images: All related Images  zygomycosis_1_060206  zygomycosis_2_060206  zygomycosis_3_060206  zygomycosis_4_060206  zygomycosis_6_060206  zygomycosis_7_060206 

DermAtlas: Histology - fungal infection, deep
© 2001-2009, DermAtlas
Image Name: zygomycosis_4_060206   File Type: jpg
Diagnosis: FUNGAL INFECTION, DEEP /
ABSCESS /
ZYGOMYCOSIS
  Category: infections and infestations
Body Site: forearm   Age: 47 years
Contributors: Greg Hosler, MD, PhD
Susan M Rabizadeh, MD
   
Description: At high power, using a Periodic Acid Schiff (PAS) stain with a light green counterstain, the features of the fungal hyphae become more clear while in a background of necrotic debris. The ribbon-like hyphae do not have parallel borders, and fail to form distinct branching angles, rather wave and twist in different directions. Septation can be difficult to evaluate, but no clear evidence of septation is seen here.
Comments: This 47-year-old man developed a necrotic ulcer with eschar and purpuric borders following immunosuppression for an orthotopic liver transplant (HCV). The lesion was biopsied and sent for both histology and cultures. The clinical differential diagnosis included deep fungal infection and ecthyma gangrenosum. The histopathology showed scattered filamentous fungi within the areas of necrosis. The apparent aseptate and ribbon-like nature of the fungus is highly suggestive of zygomycosis (mucor, rhizopus, etc), however, degenerated Aspergillus species can look like this, and thus cultures are necessary for confirmation.
Related Images: All related Images  zygomycosis_1_060206  zygomycosis_2_060206  zygomycosis_3_060206  zygomycosis_5_060206  zygomycosis_6_060206  zygomycosis_7_060206 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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