DermAtlas: Online Dermatology Image Library dermatology image,Hailey-Hailey disease,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial,pemphigus, benign familial

© 2001-2010, DermAtlas	*Image Name:*	hailey_hailey_disease_2_091120	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions, immunobullous / genodermatosis/genetic disorder
	*Body Site:*	groin / axilla (armpit)	*Age:*	45 years
	*Contributor:*	Yashpal Manchanda, MD
	*Description:*	symmetric macerated intertriginous beefy red macerated fissured plaques
	*Comments:*	A 45 year old man was evaluated for red, macerated, fissured plaques on both axillae and groin for last 20 years. The plaques worsened in the summer. His brother had similar lesions which on skin biopsy demonstrated the typical findings of benign familial pemphigus.
	*Related Images:*	hailey_hailey_disease_1_091120

© 2001-2010, DermAtlas	*Image Name:*	hailey_hailey_disease_1_091120	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions, immunobullous / genodermatosis/genetic disorder
	*Body Site:*	groin / axilla (armpit)	*Age:*	45 years
	*Contributor:*	Yashpal Manchanda, MD
	*Description:*	symmetric macerated intertriginous beefy red macerated fissured plaques
	*Comments:*	A 45 year old man was evaluated for red, macerated, fissured plaques on both axillae and groin for last 20 years. The plaques worsened in the summer. His brother had similar lesions which on skin biopsy demonstrated the typical findings of benign familial pemphigus.
	*Related Images:*	hailey_hailey_disease_2_091120

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_4_030703	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions / genodermatosis/genetic disorder
	*Body Site:*	axilla (armpit)	*Age:*	58 years
	*Contributor:*	Nathan Jones, MSIV
	*Description:*	A skin biopsy from the axilla showed suprabasilar clefting of the epidermis. There was full thickness acantholysis with some dyskeratosis near the granular layer. Within the papillary dermis there was a sparse perivascular lymphocytic infiltrate with scattered eosinophils. Direct immunoflourescence was negative.
	*Comments:*	This 58-year-old woman complained of a chronic erosive irritated intertriginous eruption for years. The histologic findings were typical of Hailey-Hailey disease or benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_1_030703 haileyhailey_2_030703 haileyhailey_3_030703

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_3_030703	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions / genodermatosis/genetic disorder
	*Body Site:*	axilla (armpit)	*Age:*	58 years
	*Contributor:*	Nathan Jones, MSIV
	*Description:*	A skin biopsy from the axilla showed suprabasilar clefting of the epidermis. There was full thickness acantholysis with some dyskeratosis near the granular layer. Within the papillary dermis there was a sparse perivascular lymphocytic infiltrate with scattered eosinophils. Direct immunoflourescence was negative.
	*Comments:*	This 58-year-old woman complained of a chronic erosive irritated intertriginous eruption for years. The histologic findings were typical of Hailey-Hailey disease or benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_1_030703 haileyhailey_2_030703 haileyhailey_4_030703

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_2_030703	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions / genodermatosis/genetic disorder
	*Body Site:*	axilla (armpit)	*Age:*	58 years
	*Contributor:*	Nathan Jones, MSIV
	*Description:*	A skin biopsy from the axilla showed suprabasilar clefting of the epidermis. There was full thickness acantholysis with some dyskeratosis near the granular layer. Within the papillary dermis there was a sparse perivascular lymphocytic infiltrate with scattered eosinophils. Direct immunoflourescence was negative.
	*Comments:*	This 58-year-old woman complained of a chronic erosive irritated intertriginous eruption for years. The histologic findings were typical of Hailey-Hailey disease or benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_1_030703 haileyhailey_3_030703 haileyhailey_4_030703

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_1_030703	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	vesiculobullous eruptions / genodermatosis/genetic disorder
	*Body Site:*	axilla (armpit) / lacrimal gland	*Age:*	58 years
	*Contributor:*	Nathan Jones, MSIV
	*Description:*	A skin biopsy from the axilla showed suprabasilar clefting of the epidermis. There was full thickness acantholysis with some dyskeratosis near the granular layer. Within the papillary dermis there was a sparse perivascular lymphocytic infiltrate with scattered eosinophils. Direct immunoflourescence was negative.
	*Comments:*	This 58-year-old woman complained of a chronic erosive irritated intertriginous eruption for years. The histologic findings were typical of Hailey-Hailey disease or benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_2_030703 haileyhailey_3_030703 haileyhailey_4_030703

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_5_011230	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	genodermatosis/genetic disorder / vesiculobullous eruptions
	*Body Site:*	back	*Age:*	28 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	round and circinate red to violaceous patches with expanding crusts and erosions at the border
	*Comments:*	A 28 year old woman complained of painful and pruritic recurrent blistering and erosions on her skin creases, back, chest, and back of the neck and scalp. She had no lesions in her mouth, and her general health was good. Her father had a similar eruption confined to intertriginous areas. Histology demonstrated the typical features of benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_2_011230 haileyhailey_3_011230 haileyhailey_4_011230

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_4_011230	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	genodermatosis/genetic disorder / vesiculobullous eruptions
	*Body Site:*	axilla (armpit)	*Age:*	28 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	round and circinate red to violaceous patches with expanding crusts and erosions at the border
	*Comments:*	A 28 year old woman complained of painful and pruritic recurrent blistering and erosions on her skin creases, back, chest, and back of the neck and scalp. She had no lesions in her mouth, and her general health was good. Her father had a similar eruption confined to intertriginous areas. Histology demonstrated the typical features of benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_2_011230 haileyhailey_3_011230 haileyhailey_5_011230

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_3_011230	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	genodermatosis/genetic disorder / vesiculobullous eruptions
	*Body Site:*	chest / abdomen	*Age:*	28 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	round and circinate red to violaceous patches with expanding crusts and erosions at the border
	*Comments:*	A 28 year old woman complained of painful and pruritic recurrent blistering and erosions on her skin creases, back, chest, and back of the neck and scalp. She had no lesions in her mouth, and her general health was good. Her father had a similar eruption confined to intertriginous areas. Histology demonstrated the typical features of benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_2_011230 haileyhailey_4_011230 haileyhailey_5_011230

© 2001-2010, DermAtlas	*Image Name:*	haileyhailey_2_011230	*File Type:*	jpg
	*Diagnosis:*	HAILEY-HAILEY DISEASE / PEMPHIGUS, BENIGN FAMILIAL	*Category:*	genodermatosis/genetic disorder / vesiculobullous eruptions
	*Body Site:*	neck / scalp	*Age:*	28 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	round and circinate red to violaceous patches with expanding crusts and erosions at the border
	*Comments:*	A 28 year old woman complained of painful and pruritic recurrent blistering and erosions on her skin creases, back, chest, and back of the neck and scalp. She had no lesions in her mouth, and her general health was good. Her father had a similar eruption confined to intertriginous areas. Histology demonstrated the typical features of benign familial pemphigus.
	*Related Images:*	All related Images haileyhailey_3_011230 haileyhailey_4_011230 haileyhailey_5_011230