DermAtlas: Online Dermatology Image Library dermatology image,tuberous sclerosis,shagreen patch,collagenoma,ash leaf macule,target lesion,nevus, connective tissue,hamartoma,nevus, connective tissue

© 2001-2010, DermAtlas	*Image Name:*	shagreen_patch_with_ash_leaf_macule_1_090518	*File Type:*	jpg
	*Diagnosis:*	TUBEROUS SCLEROSIS / SHAGREEN PATCH / COLLAGENOMA / ASH LEAF MACULE	*Category:*	genodermatosis/genetic disorder
	*Body Site:*	trunk / back	*Age:*	16 years
	*Contributor:*	Yashpal Manchanda, MD
	*Description:*	large soft to firm asymptomatic skin colored plaque and 1.5 X 0.5 cm hypopignmented macule
	*Comments:*	This mentally retarded adolescent girl with tuberous sclerosis was noted to have a shagreen patch and hypopigmented macule on her lower back at birth. She also had multiple angiofibromas on her face.

© 2001-2010, DermAtlas	*Image Name:*	collagenoma_2_090510	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / SHAGREEN PATCH / TUBEROUS SCLEROSIS	*Category:*
	*Body Site:*	forehead	*Age:*	15 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	1.5 cm pebbly brown well demarcated plaque
	*Comments:*	This healthy adolescent with tuberous sclerosis complained of irritated papules on her face and nose since elementary school and several birthmarks on her forehead, trunk, and extremities. Multiple angiofibromas on her face and small areas in the collagenomas on her forehead, left arm, and chest were treated with the Q-switched alexandrite laser at 14 J/cm2, 10 Hz, and spot size 2 mm. cooling device at level 3. Further treatment was scheduled pending the results of the test spots. This image shows the collagenoma immediately before test spots.
	*Related Images:*	All related Images angiofibroma_3_090510 angiofibroma_1_090510 angiofibroma_2_090510 collagenoma_3_090510

© 2001-2010, DermAtlas	*Image Name:*	collagenoma_3_090510	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / SHAGREEN PATCH / TUBEROUS SCLEROSIS	*Category:*
	*Body Site:*	forehead	*Age:*	15 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	1.5 cm pebbly brown well demarcated plaque
	*Comments:*	This healthy adolescent with tuberous sclerosis complained of irritated papules on her face and nose since elementary school and several birthmarks on her forehead, trunk, and extremities. Multiple angiofibromas on her face and small areas in the collagenomas on her forehead, left arm, and chest were treated with the Q-switched alexandrite laser at 14 J/cm2, 10 Hz, and spot size 2 mm. cooling device at level 3. Further treatment was scheduled pending the results of the test spots. This image shows the collagenoma immediately before test spots. This shows the collagenoma immediately after test spots were performed on the upper part of the lesion.
	*Related Images:*	All related Images angiofibroma_3_090510 angiofibroma_1_090510 angiofibroma_2_090510 collagenoma_2_090510

© 2001-2010, DermAtlas	*Image Name:*	Shagreen_patch_1_070127	*File Type:*	jpg
	*Diagnosis:*	SHAGREEN PATCH / TARGET LESION	*Category:*	genodermatosis/genetic disorder
	*Body Site:*	trunk	*Age:*	6 years
	*Contributor:*	G Alonso
	*Description:*	6 cm X 2.5 cm skin colored to slight pink-brown pebbly plaque with leathery texture and well demarcated border
	*Comments:*	This 6-year-old girl with tuberous sclerosis was managed for seizures and developmental delay. She had other features of tuberous sclerosis including this shagreen plaque on her lumbosacral area, a smaller similar plaque on the neck, and a hypopigmented patch on her posterior thorax.

© 2001-2010, DermAtlas	*Image Name:*	collagenoma_1_031110	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / NEVUS, CONNECTIVE TISSUE / SHAGREEN PATCH / HAMARTOMA	*Category:*	congenital malformation / lumps & bumps (plaques, nodules, tumors) / hypopigmentation, depigmentation
	*Body Site:*	leg / thigh	*Age:*	10 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	10 cm X 2.5 cm plaque comprised of hypopigmented 1-2 mm papules
	*Comments:*	This asymptomatic plaque, which was present at birth, grew proportionately with this healthy 10-year-old girl. She had no other skin lesions, and her growth and development were normal
	*Related Images:*	collagenoma_2_031110

© 2001-2010, DermAtlas	*Image Name:*	collagenoma_2_031110	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / NEVUS, CONNECTIVE TISSUE / SHAGREEN PATCH / HAMARTOMA	*Category:*	congenital malformation / lumps & bumps (plaques, nodules, tumors) / hypopigmentation, depigmentation
	*Body Site:*	leg / thigh	*Age:*	10 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	10 cm X 2.5 cm plaque comprised of hypopigmented 1-2 mm papules
	*Comments:*	This asymptomatic plaque, which was present at birth, grew proportionately with this healthy 10-year-old girl. She had no other skin lesions, and her growth and development were normal
	*Related Images:*	collagenoma_1_031110

© 2001-2010, DermAtlas	*Image Name:*	shagreen_patch_1_020312	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / TUBEROUS SCLEROSIS / SHAGREEN PATCH	*Category:*	cutaneous sign of systemic disease / genodermatosis/genetic disorder / neonatal dermatology
	*Body Site:*	trunk / back	*Age:*	9 years
	*Contributor:*	Ben Hidalgo-Matlock, MD
	*Description:*	fibrotic skin colored to hypopigmented cobblestone like plaque
	*Comments:*	A 9 year old girl with tuberous sclerosis demonstrates a characteristic congenital shagreen patch or collagenoma on her back.

© 2001-2010, DermAtlas	*Image Name:*	ts_2_020301	*File Type:*	jpg
	*Diagnosis:*	TUBEROUS SCLEROSIS / SHAGREEN PATCH / COLLAGENOMA	*Category:*	genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) / hyperpigmentation
	*Body Site:*	chest	*Age:*	28 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	multiple confluent 2-3 mm papules forming a pebbly brown plaque
	*Comments:*	This 28 year old man with tuberous sclerosis was evaluated for carbon dioxide laser ablation of the angiofibromas on his face. He had several congenital hypopigmented macules on the lower abdomen and thighs, a congenital shagreen patch on the upper chest, and several subungual fibromas that developed during adolescence.
	*Related Images:*	All related Images ts_1_020301 ts_3_020301 ts_4_020301

© 2001-2010, DermAtlas	*Image Name:*	ts_3_020112	*File Type:*	jpg
	*Diagnosis:*	COLLAGENOMA / TUBEROUS SCLEROSIS / SHAGREEN PATCH	*Category:*	lumps & bumps (plaques, nodules, tumors) / genodermatosis/genetic disorder
	*Body Site:*	arm / chest	*Age:*	4 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	hypopigmented dermatomal well demarcated minimally elevated plaque
	*Comments:*	A 4 year old boy with tuberous sclerosis and intractable seizures demonstrates a few yellowish-red papules on his cheeks typical of angiofibromas. He had several collagenomas or shagreen patches and multiple hypopigmented macules.
	*Related Images:*	All related Images ts_1_020112 ts_4_020112 ts_5_020112

© 2001-2010, DermAtlas	*Image Name:*	Dscn1284	*File Type:*	jpg
	*Diagnosis:*	TUBEROUS SCLEROSIS / COLLAGENOMA / SHAGREEN PATCH	*Category:*	genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	abdomen	*Age:*	17 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	hypopigmented firm superficial plaque comprised of multiple smooth topped papules
	*Comments:*	A 17 year old boy with tuberous sclerosis demonstrates many of the characteristic findings of the autosomal dominant genodermatosis. Image Dscn1282 demonstrates angiofibromas scattered around a shagreen patch on his back. Image Dscn1284 shows another shagreen patch on his abdomen, and image Dscn1285 shows angiofibromas on his nose cheeks and chin as well as pustules from acne vulgaris on his chin. Angiofibromas, particularly on the cheeks and upper lip, should not be mistaken for comedones and may suggest the diagnosis of tuberous sclerosis even in an otherwise healthy child.
	*Related Images:*	All related Images Dscn1282 Dscn1285