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DermAtlas: Histology - onychomycosis
© 2001-2009, DermAtlas
Image Name: candida_onychomycosis_1_080801   File Type: jpg
Diagnosis: ONYCHOMYCOSIS   Category: infections and infestations
Body Site: nail, foot   Age: 48 years
Contributor: Greg Hosler, MD, PhD    
Description: Histologic sections are of nail plate. Focal serm collects on the undersurface of the nail. Organisms are difficult to appreciate at this power.
Comments: Onychomycosis is a very common condition, often caused by dermatophyes. In this particular case, the organisms are budding yeast forms, most consistent with Candida spp. There is some histologic overlap between these and the spores of dermatophytes, but the presence of budding and a more dark purple color allows distinction. Additionally, there are no hyphal structures. Candida is a common cause of paronychia and may colonize the nail plate.
Related Images: candida_onychomycosis_2_080801 

DermAtlas: Histology - onychomycosis
© 2001-2009, DermAtlas
Image Name: candida_onychomycosis_2_080801   File Type: jpg
Diagnosis: ONYCHOMYCOSIS   Category: infections and infestations
Body Site: nail, foot   Age: 48 years
Contributor: Greg Hosler, MD, PhD    
Description: The organisms are evident at high power. The deep red-purple organisms are morphologically consistent with yeast. Budding elements are present. There are no hyphae or pseudohyphae in this specimen.
Comments: Onychomycosis is a very common condition, often caused by dermatophyes. In this particular case, the organisms are budding yeast forms, most consistent with Candida spp. There is some histologic overlap between these and the spores of dermatophytes, but the presence of budding and a more dark purple color allows distinction. Additionally, there are no hyphal structures. Candida is a common cause of paronychia and may colonize the nail plate.
Related Images: candida_onychomycosis_1_080801 

DermAtlas: NAIL, FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: Nail_dystrophy_1_070703   File Type: jpg
Diagnosis: ONYCHOMYCOSIS   Category: infections and infestations /
papulosquamous eruptions /
nail disorders
Body Site: nail, foot   Age: 60 years
Contributor: Mary Tonsager    
Description: yellowing and increased friability of the distal nail plates with subungual debris
Comments: This 60-year-old man complained of chronically thickened nails and pain with walking.

DermAtlas: FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: Tinea_Pedis_Onychomycosis_1_060521   File Type: jpg
Diagnosis: ONYCHOMYCOSIS /
TINEA PEDIS
  Category: infections and infestations /
nail disorders
Body Site: foot / nail, foot   Age: 67 years
Contributor: Mehrdad Mehravaran, MD    
Description: confluent red scaly plaque with well demarcated border and friable yellow nails with subungual scale
Comments: A 66-year-old woman with poor peripheral circulation complained of yellow scaly nails and progressive scaly red patches on the bottom and sides of both feet. She was treated successfully with oral terbinafine 250 mg tablet daily for 3 months. Tinea Unguium (Onychomycosis) is mycotic infection of the nail unit. The term tinea unguium is used to describe infection by dermatophytes; the term onychomycosis is nonspecific and refers to nondermatophytes and dermatophytes infections of the nail unit. Tinea unguium is generally caused by members in the genera Trichophyton and Epidermophyton and is most common in adults. T. Rubrum causes the majority of infection.

DermAtlas: TOE - onychomycosis
© 2001-2009, DermAtlas
Image Name: Onychomycosis_1_050808   File Type: jpg
Diagnosis: ONYCHOMYCOSIS /
NAIL DYSTROPHY
  Category: infections and infestations /
nail disorders
Body Site: toe / nail, foot   Age: 67 years
Contributor: Hanifa Mohamed    
Description: yellow friable nail with distal subungual debris and surrounding scale
Comments: This 67-year-old man developed a dystrophic right great toe nail. A culture grew a dermatophyte.

DermAtlas: NAIL, HAND - onychomycosis
© 2001-2009, DermAtlas
Image Name: Onychomycosis_1_050322   File Type: jpg
Diagnosis: ONYCHOMYCOSIS /
DERMATOPHYTOSIS
  Category: infections and infestations
Body Site: nail, hand   Age: 25 years
Contributor: Mahmoud Hijazy, PH.D    
Description: asymmetric yellow scaly dystrophic nails with subungual debris
Comments: This 25-year-old man developed dystrophy of several toe nails following recurrent attacks of tinea pedis inspite of long course of antifungal topical and systemic preparations. A potassium hydroxide preparation obtained from nail clippings revealed fungal hyphae.

DermAtlas: NAIL, FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: onychomycosis_2_050320   File Type: jpg
Diagnosis: ONYCHOMYCOSIS /
NAIL DYSTROPHY
  Category: nail disorders
Body Site: nail, foot   Age: 10 years
Contributor: Bernard Cohen, MD    
Description: asymmetric thickened scaly yellow nails
Comments: This 10-year-old healthy girl had a 1 year history of progressive nail dystrophy. A fungal culture obtained from scrapings of several nails grew Trichophyton rubrum, and she was started on terbinafine 100 mg/d for 3 months.
Related Images: onychomycosis_1_050320 

DermAtlas: NAIL, FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: onychomycosis_1_050320   File Type: jpg
Diagnosis: ONYCHOMYCOSIS /
NAIL DYSTROPHY
  Category: nail disorders
Body Site: nail, foot   Age: 10 years
Contributor: Bernard Cohen, MD    
Description: asymmetric thickened scaly yellow nails
Comments: This 10-year-old healthy girl had a 1 year history of progressive nail dystrophy. A fungal culture obtained from scrapings of several nails grew Trichophyton rubrum, and she was started on terbinafine 100 mg/d for 3 months.
Related Images: onychomycosis_2_050320 

DermAtlas: FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: onychomycosis_1_050228   File Type: jpg
Diagnosis: ONYCHOMYCOSIS   Category: nail disorders /
infections and infestations
Body Site: foot / nail, foot
toe
  Age: 40 years
Contributor: Shahbaz A. Janjua, MD    
Description: asymmetric yellow scaly dystrophic nails with subungual debris
Comments: This 40-year-old man developed dystrophy of several toe nails following several years of recurrent tinea pedis. A potassium hydroxide preparation obtained from nail clippings revealed fungal hyphae.
Related Images: All related Images  onychomycosis_5_050228  onychomycosis_4_050228  onychomycosis_3_050228  onychomycosis_2_050228 

DermAtlas: FOOT - onychomycosis
© 2001-2009, DermAtlas
Image Name: onychomycosis_2_050228   File Type: jpg
Diagnosis: ONYCHOMYCOSIS   Category: nail disorders /
infections and infestations
Body Site: foot / nail, foot
toe
  Age: 40 years
Contributor: Shahbaz A. Janjua, MD    
Description: asymmetric yellow scaly dystrophic nails with subungual debris
Comments: This 40-year-old man developed dystrophy of several toe nails following several years of recurrent tinea pedis. A potassium hydroxide preparation obtained from nail clippings revealed fungal hyphae.
Related Images: All related Images  onychomycosis_5_050228  onychomycosis_4_050228  onychomycosis_3_050228  onychomycosis_1_050228 

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© DermAtlas, Johns Hopkins University; 2000-2009
Bernard A. Cohen, MD, Christoph U. Lehmann, MD

DermAtlas was last updated: Oct-28-2009
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