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 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_5_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, metastatic | ||
| Body Site: | total body | Age: | 9 months | ||
| Contributor: | Susan M Rabizadeh, MD | ||||
| Description: | There is a diffuse infiltrate of the dermis and subcutis with small dark staining cells representing myeloblasts. The upper dermis is spared, and there is prominent percolation of single cells between collagen bundles. | ||||
| Comments: | These findings are typical of acute myeloid leukemia. | ||||
| Related Images: | All related Images leukemia_cutis_4_040626 leukemia_cutis_3_040626 leukemia_cutis_2_040626 leukemia_cutis_1_040626 leukemia_cutis_6_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_6_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, metastatic | ||
| Body Site: | total body | Age: | 9 months | ||
| Contributor: | Susan M Rabizadeh, MD | ||||
| Description: | There is a diffuse infiltrate of the dermis and subcutis with small dark staining cells representing myeloblasts. The upper dermis is spared, and there is prominent percolation of single cells between collagen bundles. | ||||
| Comments: | These findings are typical of acute myeloid leukemia. | ||||
| Related Images: | All related Images leukemia_cutis_4_040626 leukemia_cutis_3_040626 leukemia_cutis_2_040626 leukemia_cutis_1_040626 leukemia_cutis_5_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_1_040727 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, malignant / cutaneous sign of systemic disease / lumps & bumps (plaques, nodules, tumors) | ||
| Body Site: | leg / thigh | Age: | 29 years | ||
| Contributor: | Rachel Nussbaum, MD | ||||
| Description: | |||||
| Comments: | This 29-year-old man with acute myelogenous leukemia had a 1 week history of asymptomatic purple nodules on his legs. A skin biopsy showed a dense infiltrate of tumor cells, and a bone marrow aspirate demonstrated 95 percent blasts on a smear. | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_1_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, malignant | ||
| Body Site: | total body / face scalp | Age: | 9 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | diffuse confluent subtle indurated papules | ||||
| Comments: | A 9-month-old girl with acute lymphocytic-myeloblastic leukemia developed widely disseminated confluent asymptomatic papules. The lesions were soft but inparted a diffuse cobblestone-like texture which was best viewed with side lighting. A skin biopsy showed a nornal epidermis and sheets of tumor cells in the dermis. | ||||
| Related Images: | All related Images leukemia_cutis_4_040626 leukemia_cutis_3_040626 leukemia_cutis_2_040626 leukemia_cutis_6_040626 leukemia_cutis_5_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_2_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, malignant | ||
| Body Site: | total body / face scalp | Age: | 9 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | diffuse confluent subtle indurated papules | ||||
| Comments: | A 9-month-old girl with acute lymphocytic-myeloblastic leukemia developed widely disseminated confluent asymptomatic papules. The lesions were soft but inparted a diffuse cobblestone-like texture which was best viewed with side lighting. A skin biopsy showed a nornal epidermis and sheets of tumor cells in the dermis. | ||||
| Related Images: | All related Images leukemia_cutis_4_040626 leukemia_cutis_3_040626 leukemia_cutis_1_040626 leukemia_cutis_6_040626 leukemia_cutis_5_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_3_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, malignant | ||
| Body Site: | total body / chest abdomen / arm | Age: | 9 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | diffuse confluent subtle indurated papules | ||||
| Comments: | A 9-month-old girl with acute lymphocytic-myeloblastic leukemia developed widely disseminated confluent asymptomatic papules. The lesions were soft but inparted a diffuse cobblestone-like texture which was best viewed with side lighting. A skin biopsy showed a nornal epidermis and sheets of tumor cells in the dermis. | ||||
| Related Images: | All related Images leukemia_cutis_4_040626 leukemia_cutis_2_040626 leukemia_cutis_1_040626 leukemia_cutis_6_040626 leukemia_cutis_5_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | leukemia_cutis_4_040626 | File Type: | jpg | |
| Diagnosis: | LEUKEMIA CUTIS | Category: | neoplasm, malignant | ||
| Body Site: | total body / abdomen chest / arm | Age: | 9 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | diffuse confluent subtle indurated papules | ||||
| Comments: | A 9-month-old girl with acute lymphocytic-myeloblastic leukemia developed widely disseminated confluent asymptomatic papules. The lesions were soft but inparted a diffuse cobblestone-like texture which was best viewed with side lighting. A skin biopsy showed a nornal epidermis and sheets of tumor cells in the dermis. | ||||
| Related Images: | All related Images leukemia_cutis_3_040626 leukemia_cutis_2_040626 leukemia_cutis_1_040626 leukemia_cutis_6_040626 leukemia_cutis_5_040626 | ||||
 © 2001-2009, DermAtlas | Image Name: | CT_IVH_1_030131 | File Type: | jpg | |
| Diagnosis: | PURPURA / LEUKEMIA CUTIS / DISSEMINATED INTRAVASCULAR COAGULATION / HEMORRHAGE | Category: | neoplasm, malignant / purpura / neonatal dermatology | ||
| Body Site: | total body / brain | Age: | 3 days | ||
| Contributor: | Ari Weintraub, MD | ||||
| Description: | On the fifth day of life a grade IV intraventricular hemorrhage was noted on computed tomographic examination of the brain with extensive right temporal and basal ganglionic hemantomas as well. There was subfalcine and uncal herniation and a right to left midline shift. | ||||
| Comments: | These head scan findings were associated with rhythmic seizures and an electroencepahlogram that showed diffuse cortical dysfunction and multifocal cortical hyperirritability. His progressive downhill course was associated with development of disseminated intravascular coagulation and multiple organ dysfunction. | ||||
| Related Images: | All related Images purpura_1_030127 Skin_infiltration_1_030127 purpura_2_030127 purpura_3_030127 purpura_4_030127 purpura_5_030127 CT_IVH_3_030131 CT_IVH_2_030131 | ||||
 © 2001-2009, DermAtlas | Image Name: | CT_IVH_2_030131 | File Type: | jpg | |
| Diagnosis: | PURPURA / LEUKEMIA CUTIS / DISSEMINATED INTRAVASCULAR COAGULATION / HEMORRHAGE | Category: | neoplasm, malignant / purpura / neonatal dermatology | ||
| Body Site: | total body / brain | Age: | 3 days | ||
| Contributor: | Ari Weintraub, MD | ||||
| Description: | On the fifth day of life a grade IV intraventricular hemorrhage was noted on computed tomographic examination of the brain with extensive right temporal and basal ganglionic hematomas as well. There was subfalcine and uncal herniation and a right to left midline shift. | ||||
| Comments: | These head scan findings were associated with rhythmic seizures and an electroencepahlogram that showed diffuse cortical dysfunction and multifocal cortical hyperirritability. His progressive downhill course was associated with development of disseminated intravascular coagulation and multiple organ dysfunction. | ||||
| Related Images: | All related Images purpura_1_030127 Skin_infiltration_1_030127 purpura_2_030127 purpura_3_030127 purpura_4_030127 purpura_5_030127 CT_IVH_3_030131 CT_IVH_1_030131 | ||||
 © 2001-2009, DermAtlas | Image Name: | CT_IVH_3_030131 | File Type: | jpg | |
| Diagnosis: | PURPURA / LEUKEMIA CUTIS / DISSEMINATED INTRAVASCULAR COAGULATION / HEMORRHAGE | Category: | neoplasm, malignant / purpura / neonatal dermatology | ||
| Body Site: | total body / brain | Age: | 3 days | ||
| Contributor: | Ari Weintraub, MD | ||||
| Description: | On the fifth day of life a grade IV intraventricular hemorrhage was noted on computed tomographic examination of the brain with extensive right temporal and basal ganglionic hemantomas as well. There was subfalcine and uncal herniation and a right to left midline shift. | ||||
| Comments: | These head scan findings were associated with rhythmic seizures and an electroencepahlogram that showed diffuse cortical dysfunction and multifocal cortical hyperirritability. His progressive downhill course was associated with development of disseminated intravascular coagulation and multiple organ dysfunction. | ||||
| Related Images: | All related Images purpura_1_030127 Skin_infiltration_1_030127 purpura_2_030127 purpura_3_030127 purpura_4_030127 purpura_5_030127 CT_IVH_2_030131 CT_IVH_1_030131 | ||||
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Link directly to this page: http://DermAtlas.med.jhmi.edu/derm/result.cfm?Diagnosis=569906990