DermAtlas: Online Dermatology Image Library dermatology image,neurofibroma,neurofibromatosis,café au lait spot,neurofibroma, plexiform

© 2001-2010, DermAtlas	*Image Name:*	Neurofibroma_3_090617	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMA	*Category:*	lumps & bumps (plaques, nodules, tumors) / surgery, general
	*Body Site:*	thigh / leg	*Age:*	30 years
	*Contributor:*	Nikolaos Sferopoulos, MD
	*Description:*	soft spongy 4 cm subcutaneous tumor
	*Comments:*	A 30-year-old man developed a soft tissue tumor on the posterior aspect of his thigh 3 years ago. The tumor was excised, and pathology revealed a neurofibroma.
	*Related Images:*	All related Images Neurofibroma_2_090617 Neurofibroma_1_090617

© 2001-2010, DermAtlas	*Image Name:*	Neurofibroma_1_090617	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMA	*Category:*	lumps & bumps (plaques, nodules, tumors) / surgery, general
	*Body Site:*	thigh / leg	*Age:*	30 years
	*Contributor:*	Nikolaos Sferopoulos, MD
	*Description:*	soft spongy 4 cm subcutaneous tumor
	*Comments:*	A 30-year-old man developed a soft tissue tumor on the posterior aspect of his thigh 3 years ago. The tumor was excised, and pathology revealed a neurofibroma.
	*Related Images:*	All related Images Neurofibroma_2_090617 Neurofibroma_3_090617

© 2001-2010, DermAtlas	*Image Name:*	Neurofibroma_2_090617	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMA	*Category:*	lumps & bumps (plaques, nodules, tumors) / surgery, general
	*Body Site:*	thigh / leg	*Age:*	30 years
	*Contributor:*	Nikolaos Sferopoulos, MD
	*Description:*	soft spongy 4 cm subcutaneous tumor
	*Comments:*	A 30-year-old man developed a soft tissue tumor on the posterior aspect of his thigh 3 years ago. The tumor was excised, and pathology revealed a neurofibroma.
	*Related Images:*	All related Images Neurofibroma_1_090617 Neurofibroma_3_090617

© 2001-2010, DermAtlas	*Image Name:*	Neurofibromatosis_1_090518	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMATOSIS / CAFé AU LAIT SPOT / NEUROFIBROMA	*Category:*	neoplasm, benign / genodermatosis/genetic disorder / hyperpigmentation
	*Body Site:*	chest / abdomen arm	*Age:*	27 years
	*Contributor:*	Ravi Singh
	*Description:*	generalized soft compressible skin colored to light brownish-purple papules and nodules
	*Comments:*	This 27-year-old man had an increasing number of soft tissue tumors over much of the skin surface. He had a history of hydrocephalus which was persistent despite treatment with folk remedies.

© 2001-2010, DermAtlas	*Image Name:*	Neurofibromatosis_1_080114	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMATOSIS / NEUROFIBROMA / CAFé AU LAIT SPOT	*Category:*	genodermatosis/genetic disorder
	*Body Site:*	trunk / back	*Age:*	43
	*Contributor:*	Nasser Altamimi
	*Description:*	multiple, generalized soft spongy 2 mm-1.5 cm papules and nodules and well demarcated brown macules
	*Comments:*	This 43-year-old woman complained of multiple nodules and café au lait spots present since childhood. In addition to multiple acquired cutaneousl neurofibromas and pigmented macules, she had a single large congenital plexiform neurofibroma.

© 2001-2010, DermAtlas	*Image Name:*	neurofibroma_1_070501	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMA	*Category:*	neoplasm, neural / neoplasm, benign
	*Body Site:*	chest	*Age:*	74 years
	*Contributor:*	Greg Hosler, MD, PhD
	*Description:*	There is a fairly well-demarcated but unencapsulated spindle cell tumor within the dremis. The epidermis is uninvolved. The spindle cells are monomorphic and imperceptibly blend into the surrounding dermis. The lesion is slightly more pink than the dermal collagen.
	*Comments:*	This is a very typical example of a common lesion. The histologic differential diagnosis includes a neuritized nevus and perhaps other soft tissue tumors such as a dermatofibroma or neuroma. The lesion contains a mixture of axons, mast cells, and nerve sheath cells (fibroblasts and Schwann cells). These will stain positive for S-100 and neurofilament (scattered twigs) if needed.
	*Related Images:*	neurofibroma_2_070501

© 2001-2010, DermAtlas	*Image Name:*	neurofibroma_2_070501	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMA	*Category:*	neoplasm, neural / neoplasm, benign
	*Body Site:*	chest	*Age:*	74 years
	*Contributor:*	Greg Hosler, MD, PhD
	*Description:*	A higher power shows the very characteristic round, thin-walled vessels and the mixed nature of the tumor cells. One can identify fibroblast-like cells, Schwann cells, and scattered purple mast cells. There is no cytologic atypia or mitotic activity.
	*Comments:*	This is a very typical example of a common lesion. The histologic differential diagnosis includes a neuritized nevus and perhaps other soft tissue tumors such as a dermatofibroma or neuroma. The lesion contains a mixture of axons, mast cells, and nerve sheath cells (fibroblasts and Schwann cells). These will stain positive for S-100 and neurofilament (scattered twigs) if needed.
	*Related Images:*	neurofibroma_1_070501

© 2001-2010, DermAtlas	*Image Name:*	Neurofibromatosis_1_070311	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMATOSIS / NEUROFIBROMA	*Category:*	lumps & bumps (plaques, nodules, tumors) / genodermatosis/genetic disorder
	*Body Site:*	face / neck / neck	*Age:*	55 years
	*Contributor:*	António Matos da Fonseca, MD
	*Description:*	multiple generalized soft subcutaneous skin colored 0.3-1.5 cm ndoules
	*Comments:*	This 55-year-old man had multiple disseminated neurofibromas which had increased in number since adolescence.

© 2001-2010, DermAtlas	*Image Name:*	Neurofibromatosis_1_070208	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMATOSIS / NEUROFIBROMA, PLEXIFORM / NEUROFIBROMA	*Category:*	genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) / neoplasm, benign
	*Body Site:*	arm	*Age:*	35 years
	*Contributor:*	Indra Thakur, MD
	*Description:*	Neurofibromatosis of ARM and Forearm
	*Comments:*	This 35-year-old woman had a slowly enlarging plexiform neurofibroma on her left arm.

© 2001-2010, DermAtlas	*Image Name:*	neurofibromatosis_4_061030	*File Type:*	jpg
	*Diagnosis:*	NEUROFIBROMATOSIS / NEUROFIBROMA	*Category:*	genodermatosis/genetic disorder / lumps & bumps (plaques, nodules, tumors) / neoplasm, benign
	*Body Site:*	neck	*Age:*	50 years
	*Contributor:*	Eric Ehrsam, MD
	*Description:*	disseinated 0.3-1.0 cm fleshy pink papules and nodules
	*Comments:*	A 50-year-old man had multiple café au lait spots and cutaneous neurofibromas. He had no extracutaneous findings of neurofibromatosis.
	*Related Images:*	All related Images neurofibromatosis_1_061030 neurofibromatosis_2_061030 neurofibromatosis_3_061030