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 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_1_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / arm chest | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | generalized discrete and confluent annular red papules and plaques with peripheral scale | ||||
| Comments: | A 25-year-old man developed a recurrent annular erythematous eruption with peripheral scaling over several months. When lesions temporarily resolved, they left greyish discoloration. The differential diagnosis included erythema annulare centrifugum, pityriasis rosea (when first seen with few lesions) , and subacute cutaneous lupus erythematosus. Initially the patient forgot that he was taking a drug for dyspepsia. Later it was found to be Lansoprazole. Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis consistent with lupus. The antinuclear antibodt was positive at 1:80, while anti-Ro and anti-La antibodies were negative. Discontinuation of the Lansoprazole resulted in a complete clearance of the rash within few weeks. The pigmentary changes resolved completely. There was no recurrence of the skin lesions during a follow up period of one year. The course was typical for drug-induced lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_6_090418 drug_induced_lupus_5_090418 drug_induced_lupus_4_090418 drug_induced_lupus_3_090418 drug_induced_lupus_2_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_2_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / arm chest / abdomen | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | generalized discrete and confluent annular red papules and plaques with peripheral scale | ||||
| Comments: | A 25-year-old man developed a recurrent annular erythematous eruption with peripheral scaling over several months. When lesions temporarily resolved, they left greyish discoloration. The differential diagnosis included erythema annulare centrifugum, pityriasis rosea (when first seen with few lesions) , and subacute cutaneous lupus erythematosus. Initially the patient forgot that he was taking a drug for dyspepsia. Later it was found to be Lansoprazole. Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis consistent with lupus. The antinuclear antibodt was positive at 1:80, while anti-Ro and anti-La antibodies were negative. Discontinuation of the Lansoprazole resulted in a complete clearance of the rash within few weeks. The pigmentary changes resolved completely. There was no recurrence of the skin lesions during a follow up period of one year. The course was typical for drug-induced lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_6_090418 drug_induced_lupus_5_090418 drug_induced_lupus_4_090418 drug_induced_lupus_3_090418 drug_induced_lupus_1_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_3_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / back | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | generalized discrete and confluent annular red papules and plaques with peripheral scale | ||||
| Comments: | A 25-year-old man developed a recurrent annular erythematous eruption with peripheral scaling over several months. When lesions temporarily resolved, they left greyish discoloration. The differential diagnosis included erythema annulare centrifugum, pityriasis rosea (when first seen with few lesions) , and subacute cutaneous lupus erythematosus. Initially the patient forgot that he was taking a drug for dyspepsia. Later it was found to be Lansoprazole. Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis consistent with lupus. The antinuclear antibodt was positive at 1:80, while anti-Ro and anti-La antibodies were negative. Discontinuation of the Lansoprazole resulted in a complete clearance of the rash within few weeks. The pigmentary changes resolved completely. There was no recurrence of the skin lesions during a follow up period of one year. The course was typical for drug-induced lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_6_090418 drug_induced_lupus_5_090418 drug_induced_lupus_4_090418 drug_induced_lupus_2_090418 drug_induced_lupus_1_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_4_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / leg foot | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | generalized discrete and confluent annular red papules and plaques with peripheral scale | ||||
| Comments: | A 25-year-old man developed a recurrent annular erythematous eruption with peripheral scaling over several months. When lesions temporarily resolved, they left greyish discoloration. The differential diagnosis included erythema annulare centrifugum, pityriasis rosea (when first seen with few lesions) , and subacute cutaneous lupus erythematosus. Initially the patient forgot that he was taking a drug for dyspepsia. Later it was found to be Lansoprazole. Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis consistent with lupus. The antinuclear antibodt was positive at 1:80, while anti-Ro and anti-La antibodies were negative. Discontinuation of the Lansoprazole resulted in a complete clearance of the rash within few weeks. The pigmentary changes resolved completely. There was no recurrence of the skin lesions during a follow up period of one year. The course was typical for drug-induced lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_6_090418 drug_induced_lupus_5_090418 drug_induced_lupus_3_090418 drug_induced_lupus_2_090418 drug_induced_lupus_1_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_5_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / arm chest | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis. | ||||
| Comments: | The histologic findings are typical of lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_6_090418 drug_induced_lupus_4_090418 drug_induced_lupus_3_090418 drug_induced_lupus_2_090418 drug_induced_lupus_1_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | drug_induced_lupus_6_090418 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS / LUPUS ERYTHEMATOSUS, DRUG INDUCED / DRUG REACTION | Category: | drug reaction / collagen vascular disease | ||
| Body Site: | total body / arm chest | Age: | 25 years | ||
| Contributor: | Amr Gohar, MRCPS Glasgow | ||||
| Description: | Skin biopsy shows hyperorthokeratosis, epidermal atrophy, hydropic degeneration of the basal cell layer, and lymphocytic infiltrate of the superficial dermis. | ||||
| Comments: | The histologic findings are typical of lupus. | ||||
| Related Images: | All related Images drug_induced_lupus_5_090418 drug_induced_lupus_4_090418 drug_induced_lupus_3_090418 drug_induced_lupus_2_090418 drug_induced_lupus_1_090418 | ||||
 © 2001-2009, DermAtlas | Image Name: | neonatal_lupus_2_081108 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, NEONATAL / LUPUS ERYTHEMATOSUS | Category: | collagen vascular disease / neonatal dermatology / reactive erythema | ||
| Body Site: | face / scalp forehead / eye brow | Age: | 3 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symetric red blanching linear blanching plaques some with atrophy and fine scale | ||||
| Comments: | This healthy 3-month-old boy developed red telangiectasias with atrophy, fine scale, and some with an annular configuration on sun-exposed areas of the face and scalp during the beginning of the summer. His mother had a history of rheumatoid arthritis, and anti-Rho antibodies were positive the patient and his mother. | ||||
| Related Images: | All related Images neonatal_lupus_6_081108 neonatal_lupus_5_081108 neonatal_lupus_4_081108 neonatal_lupus_3_081108 | ||||
 © 2001-2009, DermAtlas | Image Name: | neonatal_lupus_3_081108 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, NEONATAL / LUPUS ERYTHEMATOSUS | Category: | collagen vascular disease / neonatal dermatology / reactive erythema | ||
| Body Site: | face / scalp forehead / eye brow | Age: | 3 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symetric red blanching linear blanching plaques some with atrophy and fine scale | ||||
| Comments: | This healthy 3-month-old boy developed red telangiectasias with atrophy, fine scale, and some with an annular configuration on sun-exposed areas of the face and scalp during the beginning of the summer. His mother had a history of rheumatoid arthritis, and anti-Rho antibodies were positive the patient and his mother. | ||||
| Related Images: | All related Images neonatal_lupus_6_081108 neonatal_lupus_5_081108 neonatal_lupus_4_081108 neonatal_lupus_2_081108 | ||||
 © 2001-2009, DermAtlas | Image Name: | neonatal_lupus_4_081108 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, NEONATAL / LUPUS ERYTHEMATOSUS | Category: | collagen vascular disease / neonatal dermatology / reactive erythema | ||
| Body Site: | face / scalp forehead / eye brow | Age: | 3 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symetric red blanching linear blanching plaques some with atrophy and fine scale | ||||
| Comments: | This healthy 3-month-old boy developed red telangiectasias with atrophy, fine scale, and some with an annular configuration on sun-exposed areas of the face and scalp during the beginning of the summer. His mother had a history of rheumatoid arthritis, and anti-Rho antibodies were positive the patient and his mother. | ||||
| Related Images: | All related Images neonatal_lupus_6_081108 neonatal_lupus_5_081108 neonatal_lupus_3_081108 neonatal_lupus_2_081108 | ||||
 © 2001-2009, DermAtlas | Image Name: | neonatal_lupus_5_081108 | File Type: | jpg | |
| Diagnosis: | LUPUS ERYTHEMATOSUS, NEONATAL / LUPUS ERYTHEMATOSUS | Category: | collagen vascular disease / neonatal dermatology / reactive erythema | ||
| Body Site: | face / scalp forehead / eye brow | Age: | 3 months | ||
| Contributor: | Bernard Cohen, MD | ||||
| Description: | symetric red blanching linear blanching plaques some with atrophy and fine scale | ||||
| Comments: | This healthy 3-month-old boy developed red telangiectasias with atrophy, fine scale, and some with an annular configuration on sun-exposed areas of the face and scalp during the beginning of the summer. His mother had a history of rheumatoid arthritis, and anti-Rho antibodies were positive the patient and his mother. | ||||
| Related Images: | All related Images neonatal_lupus_6_081108 neonatal_lupus_4_081108 neonatal_lupus_3_081108 neonatal_lupus_2_081108 | ||||
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