DermAtlas: Online Dermatology Image Library dermatology image,follicular mucinosis,alopecia mucinosa,syringolymphoid hyperplasia with alopecia,lymphoma, T-cell,mycosis fungoides

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_7_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	round rubbery pink 2.5 cm plaque with follicular scale
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_2_050604 follicular_mucinosis_3_050604 follicular_mucinosis_4_050604 follicular_mucinosis_5_050604 follicular_mucinosis_6_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_6_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	Attenuation of CD7 signal is noted within the intrafollicular T-cell infiltrate.
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_2_050604 follicular_mucinosis_3_050604 follicular_mucinosis_4_050604 follicular_mucinosis_5_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_5_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	CD4 marker demonstrates a predominance of CD4 T-cell population
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_2_050604 follicular_mucinosis_3_050604 follicular_mucinosis_4_050604 follicular_mucinosis_6_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_4_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	CD3 marker shows a dense intrafollicular T-cell infiltrate
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_2_050604 follicular_mucinosis_3_050604 follicular_mucinosis_5_050604 follicular_mucinosis_6_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_3_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	Alcian blue shows dense intrafollicular mucin deposition.
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_2_050604 follicular_mucinosis_4_050604 follicular_mucinosis_5_050604 follicular_mucinosis_6_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_2_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	Low power view showis mild acanthosis, cavitation of the follicular epithelium, and a minimal chronic inflammatory infiltrate within the interstitium.
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_1_050604 follicular_mucinosis_3_050604 follicular_mucinosis_4_050604 follicular_mucinosis_5_050604 follicular_mucinosis_6_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_1_050604	*File Type:*	jpg
	*Diagnosis:*	FOLLICULAR MUCINOSIS / ALOPECIA MUCINOSA	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	nose	*Age:*	5 years
	*Contributor:*	Bernard Cohen, MD
	*Description:*	CD8 staining is sparse.
	*Comments:*	This healthy 5-year-old boy developed a slowly enlarging asymptomatic plaque on his nose 2 months ago. A 2 mm punch skin biopsy showed changes characteristic of follicular mucinosis.
	*Related Images:*	All related Images follicular_mucinosis_2_050604 follicular_mucinosis_3_050604 follicular_mucinosis_4_050604 follicular_mucinosis_5_050604 follicular_mucinosis_6_050604 follicular_mucinosis_7_050604 follicular_mucinosis_8_050604 follicular_mucinosis_9_050604

© 2001-2009, DermAtlas	*Image Name:*	follicular_mucinosis_1_050211	*File Type:*	jpg
	*Diagnosis:*	ALOPECIA MUCINOSA / FOLLICULAR MUCINOSIS	*Category:*	hair disorders / collagen vascular disease / cutaneous sign of systemic disease
	*Body Site:*	eye brow / forearm face	*Age:*	21 years
	*Contributor:*	Rakhesh SV, MD
	*Description:*	multiple infiltrated skin colored papules and plaques studded with yellow 1-2 mm papules
	*Comments:*	This 21-year-old man developed focal hair loss and slowly increasing boddy swelling over the right eye brow for 5 years. The lesions were studded with yellow follicular papules with loss of hair. There was no associated loss of sensation. The histological picture of mucinous deposits in the outer root sheaths of hair follicles was consistent with the clinical diagnosis of follicular mucinosis/alopecia mucinosa. The lesions showed mild regression with intralesional corticosteroids.

© 2001-2009, DermAtlas	*Image Name:*	alopecia_mucinosa_1_030916	*File Type:*	jpg
	*Diagnosis:*	ALOPECIA MUCINOSA / FOLLICULAR MUCINOSIS	*Category:*	lumps & bumps (plaques, nodules, tumors)
	*Body Site:*	chin / face	*Age:*	10 years
	*Contributor:*	Moise Levy, MD
	*Description:*	4 cm round indurated red plaque with overlying scale
	*Comments:*	This 13-year-old girl had a firm red plaque on her chin for over 6 months. A skin biopsy showed changes typical of alopecia mucinosa. Her mother applied a product from Mexico probably containing a topical steroid, and the lesion resolved over a period of several weeks.

© 2001-2009, DermAtlas	*Image Name:*	syringolymphoidhyperplasia_4_030127	*File Type:*	jpg
	*Diagnosis:*	SYRINGOLYMPHOID HYPERPLASIA WITH ALOPECIA / ALOPECIA MUCINOSA / LYMPHOMA, T-CELL / MYCOSIS FUNGOIDES	*Category:*	neoplasm, malignant / papulosquamous eruptions / hyperpigmentation
	*Body Site:*	foot / toe	*Age:*	52 years
	*Contributor:*	Clemens Esche, MD
	*Description:*	There is a dense infiltrate of large atypical lymphocytes around an eccrine duct (syringotropism).
	*Comments:*	This 52-year-old man had a 5 year history of disseminated scaly brown papules with lesions on the feet suggesting dyshidrotic eczema. He also had red papules on his legs with complete alopecia. Biopsies from his legs showed changes typical of syringolymphoid hyperplasia with alopecia. Further studies revealed biallelic monoclonal rearrangement of the T-cell gamma chain gene typical of cutaneous T-cell lymphoma. See Esche, et al. Arch Dermatol 1998;134:753-4.
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