This 2-year-old girl had an upper respiratory tract infection 3 days before she developed a minimally pruritic red papular eruption on her face, arms, and legs with a few lesions on her palms and soles. She had copious rhinorrhea and swollen tonsils with exudate. A throad culture was sent and she started zithromycin for 3 days when the culture was reported as negative. Her respiratory symptoms began to improve, but the skin eruption persisted. Note that the eruption was most prominent on the cheeks and extensor surfaces of the arms and legs typical of Gianotti-Crosti syndrome which can be triggered by Hepatitis B virus, Epstein-Bar virus, and many other respiratory and gastrointestinal viruses. The asymptomatic or minimally pruritic eruption usually resolves without treatment or scarring over 6 to 8 weeks.
symmetric grouped discrete and confluent red edematous papules and plaques