Nephrogenic Fibrosing Dermopathy - DermAtlas

Contributor

Michael Fradley

Diagnosis

nephrogenic fibrosing dermopathy

Body Site

thigh

Age

54 years

Pigmentation

Organization

confluent

Color

skin color

Morphology

plaqulous (plaque / nodule / tumor)

Pattern

symmetric acral (centripetal - extremity predominant)

Comments

These histologic findings in the setting of a renal failure and renal dialysis and the presence of diffuse of diffuse fibrosis of the extremities are characteristic of nephrogenic fibrosing dermopathy.

Description

On low power the biopsy has a square configuration consistent with a fibrosing disorder. The dermis is thickened with haphazardly arranged collagen bundles associated with increased numbers of fibroblasts. In the mid to deep dermis there is a diffuse interstitial mononuclear infilitrate. Widening of the interlobular septa in the subcutaneous fat is also noted.

Image Added

5/31/2003 12:41:36

Translate

Other Resources

PubMed Medline Plus Medscape

Image Options

View Image in New Window