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Contributor

Simon Yoo, MD

Diagnosis

drug reaction keratoderma, palmoplantar drug reaction, calcium channel blocker

Body Site

palm hand

Age

48 years

Pigmentation

light

Organization

confluent

Color

red yellow

Morphology

papulosquamous (bump, scale)

Pattern

symmetric acral (centripetal - extremity predominant)

Comments

The histologic changes are consistent with a drug reaction.

Description

There is a superficial lymphocytic perivascular and interface infiltrate with vacuolar change in the basal cell layer of the epidermis and scattered dyskeratotic keratinocytes.

Categories

papulosquamous eruptions Iatrogenic disorders, child abuse,

Image Added

11/17/2002 21:13:53

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Other Resources

PubMed Medline Plus Medscape

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