Hyperpigmentation, Congenital, Universal Dyschromatosis, Dyschromatosis Universalis - DermAtlas

Contributor

Patrice Plantin, MD

Diagnosis

hyperpigmentation, congenital universal dyschromatosis dyschromatosis universalis

Body Site

trunk

Age

9 years

Pigmentation

dark

Organization

confluent

Color

Morphology

macular / flat (macule / patch)

Pattern

Comments

Universal dyschromatosis (UD) is a generalized leucomelanodermia described in Japan in 1933. Transmission is dominant with variable expression. UD is characterized by alternating hypo and hyperpigmented macules of varying size. The face and the extremities are spared. The dyspigmentation resembles the pigmentary changes of xeroderma pigmentosum, but patients with UD do not demonstrate photosensitivity, defects in DNA repair or an increased risk of skin cancer. The incidence of DU is highest in the French Carribbean islands.

Description

mottled confluent hyper and hypopigmented macules

Image Added

11/4/2001 9:21:47

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Other Resources

PubMed Medline Plus Medscape

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