Fox-Fordyce Disease - DermAtlas - Dermatology Image Atlas

Contributor

Adam Mamalek

Diagnosis

Fox-Fordyce disease

Body Site

axilla (armpit)

Age

19 years

Pigmentation

dark

Organization

grouped, clustered

Color

brown

Morphology

papule

Pattern

symmetric intertrigenous (creases)

Comments

A 19-year-old woman complained of itchy bumps in her arm pits since age 10. Symptoms worsened with the application of certain deodorants. Fox-Fordyce disease is a chronic pruritic papular eruption that occurs in apocrine gland-containing areas. Keratin is believed to plug in the hair follicle infundibulum causing an obstruction of the apocrine acrosyringium. This leads to apocrine anhidrosis and potentially, rupture of the apocrine excretory duct with a resultant inflammatory response and intense pruritus. Fox-Fordyce disease is much more common in women (M:F 9:1) typically 13-35 years of age.

Description

symmetric uniform grouped 2-3 mm hyperpigmented papules

Image Added

6/11/2006 17:29:44

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Other Resources

PubMed Medline Plus Medscape

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