Drug Reaction, Methotrexate, Drug Reaction, Ulcer - DermAtlas

Contributor

Jamie Loveless

Diagnosis

drug reaction, methotrexate drug reaction ulcer

Body Site

hand

Age

52 years

Pigmentation

light

Organization

discrete

Color

yellow white/hypo

Morphology

ulcerated (erosion / ulcer)

Pattern

symmetric

Comments

Cultures for bacteria, fungus, and atypical mycobacteria were negative. The findings were not specific but consistent with drug induced necrosis and subsequent ulceration

Description

Biopsy at the edge of the ulcer on left buttocks reveals necrosis of the epidermis, deep dermis and subcutaneous fat. Features of vasculitis and vasculopathy are not seen. A significant inflammatory infiltrate is not present. DIF is negative.

Image Added

12/16/2006 23:43:23

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Other Resources

PubMed Medline Plus Medscape

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