Bullous Pemphigoid - DermAtlas - Dermatology Image Atlas

Contributor

Katsuya Hisamichi, MD

Diagnosis

bullous pemphigoid

Body Site

arm total body arm

Age

82 years

Pigmentation

light

Organization

grouped, clustered

Color

red yellow

Morphology

vesiculobullous (blister, pustule)

Pattern

generalized, disseminated

Comments

An 82-year-old woman developed itchy tense bullae on a red base over her arms, trunk, and legs over 2 months. Mucous membranes were spared. A skin biopsy showed a subepidermal blister and direct immunofluorescence demonstrated IgG and C3 on the blister roof and floor related to the hemidesmosome antigens BP230 and BP180.

Description

There is a subepidermal blister containing a mixed infiltrate of lymphocytes, eosinophils, and neutrophils. A lymphocytic infiltrate is seen in the dermis.

Image Added

10/5/2008 16:45:22

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Other Resources

PubMed Medline Plus Medscape

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