Epidermolysis Bullosa, Junctional, Epidermolysis Bullosa, Epidermolysis Bullosa, Dominant Junctional - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

epidermolysis bullosa, junctional epidermolysis bullosa epidermolysis bullosa, dominant junctional

Body Site

foot

Age

3 years

Pigmentation

dark

Organization

grouped, clustered

Color

purple red

Morphology

vesiculobullous (blister, pustule)

Pattern

acral (centripetal - extremity predominant)

Comments

This preshooler demonstrates recurrent bullae in various stages of healing on her her feet. Although she occasionally developed bullae on the trunk, most of her lesions were restricted to her hands and feet like her younger sister and father. Electron microscopy examination of skin from her father showed decreased number of abnormal hemidesmosomes consistent with junctional epidermolysis bullosa.

Description

symmetric acral bullae, hemorrhagic bullae, erosions, crusts, and desquamation around healing lesions

Image Added

7/26/2010 22:38:26

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Other Resources

PubMed Medline Plus Medscape

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