Sarcoidosis, Granulomatous Reaction - DermAtlas

Contributor

Greg Hosler, MD, PhD

Diagnosis

sarcoidosis granulomatous reaction

Body Site

back

Age

39 years

Pigmentation

dark

Organization

discrete

Color

purple

Morphology

plaqulous (plaque / nodule / tumor)

Pattern

localized

Comments

These are typical examples of sarcoidal (non-caseating, tightly formed) granulomas. Infectious etiologies, i.e. fungal and mycobacterial, are in the histologic differential diagnosis and therefore it is prudent to perform special stains for these entities. In this case, fungal stains (PAS/light green) and mycobacterial stains (Kinyoun's AFB) were negative.

Description

Higher power demonstrates well-demarcated, tightly formed non-caseating granulomas. Scattered multinucleated giant cells are present.

Image Added

1/5/2006 21:55:52

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PubMed Medline Plus Medscape

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