Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

toxic epidermal necrolysis Stevens-Johnson syndrome

Body Site

total body leg

Age

5 years

Pigmentation

light

Organization

confluent

Color

red

Morphology

vesiculobullous (blister, pustule)

Pattern

symmetric generalized, disseminated

Comments

This 5-year-old boy, who was on no medications, developed fever and sore throat followed 3 days later by an erosive conjunctivitis, oral mucositis, urethritis, and a progressive generalized erythema, blistering, and ulcerations. He was admitted to the intensive care unit where he received pulsed high dose intravenous steroids and intravenous immunoglobulin 2 grams/kg over 3 days, but continued to progress to 100% skin and mucous membrane involvement. Over the subsequent 4 weeks he gradually improved and was discharged from the acute care hospital to a longterm pediatric facility for occupational and physical therapy.

Description

Generalized erythema, blistering, and erosions

Image Added

7/25/2010 10:06:24

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PubMed Medline Plus Medscape

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