Wells Syndrome - DermAtlas - Dermatology Image Atlas

Contributor

Greg Hosler, MD, PhD

Diagnosis

Wells syndrome

Body Site

arm

Age

79 years

Pigmentation

light

Organization

ill defined

Color

red brown

Morphology

plaqulous (plaque / nodule / tumor)

Pattern

solitary

Comments

Wells syndrome, or eosinophilic cellulitis, is an exuberant eosinophlic reaction, possibly to an arthropod bite. The characteristic finding on histology is the flame figures, seen in this case, which are collections of degranulating eosinophils. Without clinical history, other thoughts include drug eruptions or hypereosinophilic syndrome.

Description

There is an infiltrate in the dermis. The epidermis is uninvolved. The infiltrate is somewhat nodular, in a perivascular distribution. It extends to the deep dermis.

Image Added

12/14/2009 16:18:16

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Other Resources

PubMed Medline Plus Medscape

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