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Contributor

Eric Ehrsam, MD

Diagnosis

Bazex syndrome acrokeratosis paraneoplastica nail dystrophy

Body Site

hand foot nail, all

Age

70 years

Pigmentation

light

Organization

Color

red

Morphology

papulosquamous (bump, scale)

Pattern

symmetric acral (centripetal - extremity predominant)

Comments

A 70 year old man developed a psoriasiform dermatitis of the fingers, toes and ears (helix). He had a destructive nail dystrophy. A few weeks later the patient also developed cervical adenopathy. Otolaryngologic investigations revealed a layngeal squamous cell carcinoma.The Bazex syndrome or acrokeratosis paraneoplastica is a rare dermatosos associated with carcinomas of the upper aerodigestive tract with possible lymph node mestastases. The cutaneous lesions occuring in the syndrome are non metastatic skin involvment. The psoriasiform lesions often precede the diagnosis of the associated malignancy, or occur simultaneously. The reapparance of skin lesions may signal a recurrence of the tumor. Treatment consists in treatment of the underlying cancer. In some cases, acitretin or oral psoralen phototherapy could be prescribed.

Description

symmetric erythematous scaly patches with yellowing and scaling of the nails

Categories

paraneoplastic syndrome papulosquamous eruptions nail disorders

Image Added

5/2/2002 11:21:15

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Other Resources

PubMed Medline Plus Medscape

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