Botryomycosis, Splendore-Hoeppli Phenomenon, Mycetoma - DermAtlas

Contributor

Greg Hosler, MD, PhD

Diagnosis

botryomycosis Splendore-Hoeppli phenomenon mycetoma

Body Site

leg

Age

51 years

Pigmentation

light

Organization

scattered

Color

brown

Morphology

ulcerated (erosion / ulcer)

Pattern

acral (centripetal - extremity predominant)

Comments

This 51-year-old woman had chronic ulcers of her lower extremities. Botryomycosis is an unusual finding in skin biopsies. The lesions are similar to mycetoma, but the the central areas are bacterial colonies (often Staphylococcus aureus) and not filamentous fungi. Immunoglobulin is abundant within the concretions. These structures have a characteristic brightly eosinophilic peripheral band, the Splendore-Hoeppli phenomenon.

Description

At high power, the center of the concretion consists of basophilic granular material. A brightly eosinophilic band encases the bacteria.

Image Added

4/14/2006 8:42:31

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Other Resources

PubMed Medline Plus Medscape

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