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Contributor

Greg Hosler, MD, PhD

Diagnosis

calcinosis cutis

Body Site

buttock

Age

23 years

Pigmentation

dark

Organization

discrete

Color

brown

Morphology

plaqulous (plaque / nodule / tumor)

Pattern

solitary

Comments

This 23-year-old male had a nodule on his buttock, submitted to rule out dermatofibroma. Calcinosis cutis comes in a variety of flavors, this case representing a form a dystrophic calcification. Dystrophic calcification is usually secondary to trauma, although this history was not elicited in our patient. The buttock is often subject to trauma. The histology in this case is typical. The presence of calcium is often unambiguous on hematoxylin and eosin sections, but if in doubt, a von Kossa stain can help.

Description

At higher power, the desposits are deeply basophilic and crystalline, consistent with calcium pyrophosphate. The size of the material ranges from granular to large polyhedral chunks. There is artifactual cracking and retraction spaces. The surrounding dermis is fibrotic with only a minimal inflammatory reaction.

Categories

Metabolic disorders environmental injury

Image Added

3/7/2006 22:35:49

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Other Resources

PubMed Medline Plus Medscape

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