This 56-year-old woman had a lesion on her occipital scalp. The clinician felt it was a nevus. This is a typical presentation as they often occur on the scalp of a middle-age-to-elderly person. These are thought to be of eccrine origin. We sign these out as benign mixed tumor of the skin (chondroid syringoma) as its classification is in evolution.
At higher power of the same lesion, the eccrine origin of this lesion becomes more evident. The small, tadpole-like glands (syringoma-like) are lined by two cell layers. They focally coalesce into pseudocribriform structures. The cells are cytologically bland and no mitotic figures are present. The surrounding matrix has a myxo-chondroid appearance.