Bullous Pemphigoid, Chronic Bullous Disease Of Childhood - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

bullous pemphigoid chronic bullous disease of childhood

Body Site

total body abdomen chest

Age

6 years

Pigmentation

light

Organization

annular serpiginous discrete confluent

Color

red

Morphology

plaqulous (plaque / nodule / tumor)

Pattern

generalized, disseminated symmetric

Comments

This 6-year-old girl with a history of biliary atresia and who received a liver transplant 5 years ago developed a progressive itchy blistering eruption 1 month ago. While awaiting the results of a skin biopsy she was treated for presumed linear IgA bullous disease of childhood with oral dapsone without improvement. The biopsy showed a subepidermal vesicle, and direct immunofluorescence revealed C3 and immunoglobulin G along the basement membrane zone typical of bullous pemphigoid. The eruption cleared over 2 weeks on oral prednisolone 1 mg/kg/day.

Description

generalized discrete and confluent serpiginous annular edematous red plaques with crusted papules and vesicles at the periphery

Image Added

4/17/2010 23:10:25

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PubMed Medline Plus Medscape

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