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Contributor

Bernard Cohen, MD

Diagnosis

linear IgA dermatosis chronic bullous disease of childhood

Body Site

total body leg foot

Age

10 months

Pigmentation

dark

Organization

grouped, clustered scattered

Color

red

Morphology

vesiculobullous (blister, pustule)

Pattern

generalized, disseminated symmetric intertrigenous (creases)

Comments

This healthy6 10-month-old boy developed a generalized vesiculobullous eruption with densest lesions on his neck, chin, and diaper area a week ago. His mucous membranes were clear, he was afebrile, he was eating well, and his behavior was normal except for itching particularly around his neck. Indirect immunosluorescence on salt split skin demonstrated linear deposition of IgA within the basement membrane zone. A complete blood count and G6PD were normal. He started oral dapsone 0.5 mg/kg/day and the eruption improved dramatically within 48 hours.

Description

widespread 3 mm-1 cm vesicles and bullae many with central crusting and surrounding intact vesicles and some on a red base while others have surrounding normal skin

Categories

vesiculobullous eruptions vesiculobullous eruptions, immunobullous

Image Added

1/30/2011 12:19:31

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Other Resources

PubMed Medline Plus Medscape

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