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Contributor

Greg Hosler, MD, PhD

Diagnosis

dermatitis herpetiformis

Body Site

hip elbow

Age

70 years

Pigmentation

light

Organization

grouped, clustered

Color

skin color

Morphology

papule

Pattern

extensor surfaces

Comments

This 70 year old man presented with pruritic grouped vesicles on his extensor surfaces. This is a characteristic presentation with great pathology. The histology in this case is classic, with aggregates of neutrophils in the dermal papillae. The immunofluoresence was performed and confirmed the presence of IgA deposition in these papillae, but the diagnosis could be made on H&E. The differential diagnosis includes linear IgA disease, but the prominent dermal papillary aggegates would be unusual for that entity.

Description

At higher power, there is a classic display of neutrophilic aggregates in the dermal papillae. Neutrophils also align along the junction. Scattered eosinophils are also noted.

Categories

vesiculobullous eruptions

Image Added

9/2/2008 22:09:14

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Other Resources

PubMed Medline Plus Medscape

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